3EH0

Crystal Structure of LpxD from Escherichia coli

Summary for 3EH0

DescriptorUDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase (2 entities in total)
Functional Keywordslpxd, acyltransferase, left-handed parallel beta helix, acyl carrier protein, antibiotic resistance, lipid a biosynthesis, lipid synthesis, transferase
Biological sourceEscherichia coli
Total number of polymer chains3
Total molecular weight108136.04
Authors
Bartling, C.M.,Raetz, C.R.H. (deposition date: 2008-09-11, release date: 2009-08-18, Last modification date: 2011-07-13)
Primary citation
Bartling, C.M.,Raetz, C.R.
Crystal structure and acyl chain selectivity of Escherichia coli LpxD, the N-acyltransferase of lipid A biosynthesis
Biochemistry, 48:8672-8683, 2009
PubMed: 19655786 (PDB entries with the same primary citation)
DOI: 10.1021/bi901025v
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.6 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.273110.3%0.7%6.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload