3EH0

Crystal Structure of LpxD from Escherichia coli

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006629	biological_process	lipid metabolic process
A	0009245	biological_process	lipid A biosynthetic process
A	0016020	cellular_component	membrane
A	0016410	molecular_function	N-acyltransferase activity
A	0016740	molecular_function	transferase activity
A	0016746	molecular_function	acyltransferase activity
A	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
A	0042802	molecular_function	identical protein binding
A	0046677	biological_process	response to antibiotic
A	0103118	molecular_function	UDP-3-O-[(3R)-3-hydroxyacyl]-glucosamine N-acyltransferase activity
B	0005515	molecular_function	protein binding
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006629	biological_process	lipid metabolic process
B	0009245	biological_process	lipid A biosynthetic process
B	0016020	cellular_component	membrane
B	0016410	molecular_function	N-acyltransferase activity
B	0016740	molecular_function	transferase activity
B	0016746	molecular_function	acyltransferase activity
B	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
B	0042802	molecular_function	identical protein binding
B	0046677	biological_process	response to antibiotic
B	0103118	molecular_function	UDP-3-O-[(3R)-3-hydroxyacyl]-glucosamine N-acyltransferase activity
C	0005515	molecular_function	protein binding
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0006629	biological_process	lipid metabolic process
C	0009245	biological_process	lipid A biosynthetic process
C	0016020	cellular_component	membrane
C	0016410	molecular_function	N-acyltransferase activity
C	0016740	molecular_function	transferase activity
C	0016746	molecular_function	acyltransferase activity
C	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
C	0042802	molecular_function	identical protein binding
C	0046677	biological_process	response to antibiotic
C	0103118	molecular_function	UDP-3-O-[(3R)-3-hydroxyacyl]-glucosamine N-acyltransferase activity

Functional Information from PROSITE/UniProt

site_id	PS00101
Number of Residues	29
Details	HEXAPEP_TRANSFERASES Hexapeptide-repeat containing-transferases signature. IApsAvIdatAkLGnnVsIGanAvIesgV

Chain	Residue	Details
A	ILE100-VAL128
A	ILE106-VAL134
A	LEU130-VAL158
A	ILE225-VAL253

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"PubMed","id":"18422345","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	3
Details	Site: {"description":"Involved in determining the hydroxyacyl-ACP selectivity"}

Chain

Residue

Details

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	1
Details	Annotated By Reference To The Literature 1lxa

Chain	Residue	Details
A	HIS239

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site_id	CSA2
Number of Residues	1
Details	Annotated By Reference To The Literature 1lxa

Chain	Residue	Details
B	HIS239

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site_id	CSA3
Number of Residues	1
Details	Annotated By Reference To The Literature 1lxa

Chain	Residue	Details
C	HIS239

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