3EMB

Wesselsbron virus Methyltransferase in complex with AdoMet and 7MeGpppG

Summary for 3EMB

Entry DOI	10.2210/pdb3emb/pdb
Related	3ELD 3ELU 3ELW 3ELY 3EMD
Descriptor	Methyltransferase, S-ADENOSYLMETHIONINE, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, ... (5 entities in total)
Functional Keywords	flavivirus, rna capping, methyltransferase, guanylyltransferase, viral enzyme structure, transferase
Biological source	Wesselsbron virus
Cellular location	Envelope protein E: Virion membrane; Multi- pass membrane protein: C8XPB0
Total number of polymer chains	1
Total formula weight	35587.17
Authors	Bollati, M.,Ricagno, S.,Milani, M.,Mastrangelo, E.,Bolognesi, M. (deposition date: 2008-09-24, release date: 2008-11-18, Last modification date: 2023-11-01)
Primary citation	Bollati, M.,Milani, M.,Mastrangelo, E.,Ricagno, S.,Tedeschi, G.,Nonnis, S.,Decroly, E.,Selisko, B.,de Lamballerie, X.,Coutard, B.,Canard, B.,Bolognesi, M. Recognition of RNA Cap in the Wesselsbron Virus NS5 Methyltransferase Domain: Implications for RNA-Capping Mechanisms in Flavivirus J.Mol.Biol., 385:140-152, 2009 Cited by PubMed: 18976670 DOI: 10.1016/j.jmb.2008.10.028 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation