3EMB

Wesselsbron virus Methyltransferase in complex with AdoMet and 7MeGpppG

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004482	molecular_function	mRNA 5'-cap (guanine-N7-)-methyltransferase activity
A	0004483	molecular_function	methyltransferase cap1 activity
A	0006370	biological_process	7-methylguanosine mRNA capping
A	0008168	molecular_function	methyltransferase activity
A	0032259	biological_process	methylation
A	0106005	biological_process	RNA 5'-cap (guanine-N7)-methylation

Functional Information from PDB Data

site_id	AC1
Number of Residues	18
Details	BINDING SITE FOR RESIDUE SAM A4633

Chain	Residue
A	SER56
A	GLU111
A	SER130
A	ASN131
A	VAL132
A	PHE133
A	ASP146
A	HOH4646
A	HOH4651
A	HOH4680
A	GLY58
A	GLY81
A	CYS82
A	GLY83
A	GLY86
A	TRP87
A	THR104
A	LEU105

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site_id	AC2
Number of Residues	17
Details	BINDING SITE FOR RESIDUE GTG A4634

Chain	Residue
A	LYS13
A	LEU16
A	ASN17
A	LEU19
A	PHE24
A	ARG57
A	SER150
A	SER151
A	SER152
A	GLU193
A	ARG197
A	SER215
A	SO44636
A	HOH4766
A	HOH4776
A	HOH4809
A	HOH4810

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site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A4635

Chain	Residue
A	ARG37
A	ARG41
A	ARG57
A	ARG84

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site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A4636

Chain	Residue
A	GLY58
A	LYS61
A	GTG4634
A	HOH4824

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