PDB: 1170 件ウェブページステータス検索Chemie searchBIRD

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3ZL1	A thiazolyl-mannoside bound to FimH, monoclinic space group 分子名称: CHLORIDE ION, N-{5-[(1R)-1-hydroxyethyl]-1,3-thiazol-2-yl}-alpha-D-mannopyranosylamine, PROTEIN FIMH 著者 Brument, S, Sivignon, A, Dumych, T.I, Moreau, N, Roos, G, Guerardel, Y, Chalopin, T, Deniaud, D, Bilyy, R.O, Darfeuille-Michaud, A, Bouckaert, J, Gouin, S.G. 登録日 2013-01-27 公開日 2013-07-10 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.551 Å) 主引用文献 Thiazolylaminomannosides as Potent Antiadhesives of Type 1 Piliated Escherichia Coli Isolated from Crohn'S Disease Patients. J.Med.Chem., 56, 2013
3ZL2	A thiazolyl-mannoside bound to FimH, orthorhombic space group 分子名称: N-{5-[(1R)-1-hydroxyethyl]-1,3-thiazol-2-yl}-alpha-D-mannopyranosylamine, PROTEIN FIMH 著者 Brument, S, Sivignon, A, Dumych, T.I, Moreau, N, Roos, G, Guerardel, Y, Chalopin, T, Deniaud, D, Bilyy, R.O, Darfeuille-Michaud, A, Bouckaert, J, Gouin, S.G. 登録日 2013-01-27 公開日 2013-07-10 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.251 Å) 主引用文献 Thiazolylaminomannosides as Potent Antiadhesives of Type 1 Piliated Escherichia Coli Isolated from Crohn'S Disease Patients. J.Med.Chem., 56, 2013
3GBG	Crystal Structure of ToxT from Vibrio Cholerae O395 分子名称: PALMITOLEIC ACID, TCP pilus virulence regulatory protein 著者 Lowden, M.J, Kull, F.J. 登録日 2009-02-19 公開日 2010-02-23 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure of Vibrio cholerae ToxT reveals a mechanism for fatty acid regulation of virulence genes. Proc.Natl.Acad.Sci.USA, 107, 2010
3CI0	The Crystal Structure of the GspK-GspI-GspJ complex from enterotoxigenic Escherichia coli Type 2 Secretion System 分子名称: CALCIUM ION, CHLORIDE ION, Pseudopilin GspI, ... 著者 Korotkov, K.V, Hol, W.G.J. 登録日 2008-03-10 公開日 2008-04-29 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure of the GspK-GspI-GspJ complex from the enterotoxigenic Escherichia coli type 2 secretion system. Nat.Struct.Mol.Biol., 15, 2008
7SU1	Crystal structure of an acidic pH-selective Ipilimumab variant Ipi.106 in complex with CTLA-4 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Cytotoxic T-lymphocyte protein 4, Fab heavy chain, ... 著者 Lee, P.S, Chau, B, Strop, P. 登録日 2021-11-15 公開日 2022-03-02 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.53 Å) 主引用文献 Improved therapeutic index of an acidic pH-selective antibody. Mabs, 14, 2022
7SU0	Crystal structure of an acidic pH-selective Ipilimumab variant Ipi.105 in complex with CTLA-4 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CITRATE ANION, Cytotoxic T-lymphocyte protein 4, ... 著者 Lee, P.S, Chau, B, Strop, P. 登録日 2021-11-15 公開日 2022-03-02 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.41 Å) 主引用文献 Improved therapeutic index of an acidic pH-selective antibody. Mabs, 14, 2022
7T4S	CryoEM structure of the HCMV Pentamer gH/gL/UL128/UL130/UL131A in complex with NRP2 and neutralizing fabs 8I21 and 13H11 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Envelope glycoprotein H, ... 著者 Kschonsak, M, Johnson, M.C, Schelling, R, Green, E.M, Rouge, L, Ho, H, Patel, N, Kilic, C, Kraft, E, Arthur, C.P, Rohou, A.L, Comps-Agrar, L, Martinez-Martin, N, Perez, L, Payandeh, J, Ciferri, C. 登録日 2021-12-10 公開日 2022-03-23 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural basis for HCMV Pentamer receptor recognition and antibody neutralization. Sci Adv, 8, 2022
5C7G	Crystal Structure of the b1 Domain of Human Neuropilin-1 in complex with a bicine molecule 分子名称: BICINE, Neuropilin-1, SODIUM ION 著者 Didierjean, C, Jelsch, C. 登録日 2015-06-24 公開日 2016-07-06 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Design, synthesis and biological evaluation of new peptidomimetic compounds targeting NRP-1 receptor TO BE PUBLISHED To Be Published
4TWN	Human EphA3 Kinase domain in complex with Birb796 分子名称: 1-(5-TERT-BUTYL-2-P-TOLYL-2H-PYRAZOL-3-YL)-3-[4-(2-MORPHOLIN-4-YL-ETHOXY)-NAPHTHALEN-1-YL]-UREA, Ephrin type-A receptor 3 著者 Dong, J, Caflisch, A. 登録日 2014-07-01 公開日 2015-05-13 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.706 Å) 主引用文献 Structural Analysis of the Binding of Type I, I1/2, and II Inhibitors to Eph Tyrosine Kinases. Acs Med.Chem.Lett., 6, 2015
7B7G	BAZ2A bromodomain in complex with compounds MS04 and B11 分子名称: 1-[1-(3,5-dimethoxyphenyl)piperidin-4-yl]-2,3-dimethyl-guanidine, 5-ethyl-2-(3-methyl-1,2,3-triazol-4-yl)-1~{H}-benzimidazole, Bromodomain adjacent to zinc finger domain protein 2A 著者 Dalle Vedove, A, Cazzanelli, G, Sedykh, M, Caflisch, A, Lolli, G. 登録日 2020-12-10 公開日 2021-10-20 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.428 Å) 主引用文献 Identification of a BAZ2A-Bromodomain Hit Compound by Fragment Growing. Acs Med.Chem.Lett., 13, 2022
7B82	BAZ2A bromodomain in complex with triazole compound MS04-TN03 分子名称: (2~{S})-1-[4-[[(~{E})-~{N},~{N}'-dimethylcarbamimidoyl]amino]phenyl]-~{N}-[[2-(3-methyl-1,2,3-triazol-4-yl)-1~{H}-benzimidazol-5-yl]methyl]pyrrolidine-2-carboxamide, Bromodomain adjacent to zinc finger domain protein 2A 著者 Dalle Vedove, A, Cazzanelli, G, Sedykh, M, Caflisch, A, Lolli, G. 登録日 2020-12-12 公開日 2021-10-20 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 Identification of a BAZ2A-Bromodomain Hit Compound by Fragment Growing. Acs Med.Chem.Lett., 13, 2022
7B7I	BAZ2A bromodomain in complex with triazole compound MS04-TN02 分子名称: 2-[4-[[(~{E})-~{N},~{N}'-dimethylcarbamimidoyl]amino]piperidin-1-yl]-~{N}-[[2-(3-methyl-1,2,3-triazol-4-yl)-1~{H}-benzimidazol-5-yl]methyl]ethanamide, Bromodomain adjacent to zinc finger domain protein 2A 著者 Dalle Vedove, A, Cazzanelli, G, Sedykh, M, Caflisch, A, Lolli, G. 登録日 2020-12-10 公開日 2021-10-20 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.15 Å) 主引用文献 Identification of a BAZ2A-Bromodomain Hit Compound by Fragment Growing. Acs Med.Chem.Lett., 13, 2022
7B7B	BAZ2A bromodomain in complex with triazole compound MS04 分子名称: 5-ethyl-2-(3-methyl-1,2,3-triazol-4-yl)-1~{H}-benzimidazole, Bromodomain adjacent to zinc finger domain protein 2A 著者 Dalle Vedove, A, Cazzanelli, G, Sedykh, M, Caflisch, A, Lolli, G. 登録日 2020-12-10 公開日 2021-10-20 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Identification of a BAZ2A-Bromodomain Hit Compound by Fragment Growing. Acs Med.Chem.Lett., 13, 2022
3UIZ	Crystal structure of SefD_dscA in D2O 分子名称: Chimera protein of SefD and SefA 著者 Garnett, J.A, Wei-chao, L, Liu, B, Matthews, S.J. 登録日 2011-11-07 公開日 2012-05-02 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Promoting crystallisation of the Salmonella enteritidis fimbriae 14 pilin SefD using deuterium oxide. Biochem.Biophys.Res.Commun., 421, 2012
3UIY	Crystal structure of SefD_dscA in H2O 分子名称: Chimera protein of SefD and SefA 著者 Garnett, J.A, Wei-chao, L, Liu, B, Matthews, S.J. 登録日 2011-11-07 公開日 2012-05-02 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Promoting crystallisation of the Salmonella enteritidis fimbriae 14 pilin SefD using deuterium oxide. Biochem.Biophys.Res.Commun., 421, 2012
7O0E	Crystal structure of GH30 (mutant E188A) complexed with aldotriuronic acid from Thermothelomyces thermophila. 分子名称: 1,2-ETHANEDIOL, 4-O-methyl-alpha-D-glucopyranuronic acid-(1-2)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose, DI(HYDROXYETHYL)ETHER, ... 著者 Dimarogona, M, Kosinas, C, Feiler, C, Weiss, M.S, Topakas, E, Nikolaivits, E. 登録日 2021-03-26 公開日 2021-09-08 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Unique features of the bifunctional GH30 from Thermothelomyces thermophila revealed by structural and mutational studies Carbohydrate Polymers, 273, 2021
7F59	DNQX-bound GluK2-1xNeto2 complex 分子名称: (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ... 著者 He, L.L, Gao, Y.W, Li, B, Zhao, Y. 登録日 2021-06-21 公開日 2021-09-29 最終更新日 2021-12-01 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Kainate receptor modulation by NETO2. Nature, 599, 2021
7F56	DNQX-bound GluK2-1xNeto2 complex, with asymmetric LBD 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, kainate 2, ... 著者 He, L.L, Gao, Y.W, Li, B, Zhao, Y. 登録日 2021-06-21 公開日 2021-09-29 最終更新日 2021-12-01 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Kainate receptor modulation by NETO2. Nature, 599, 2021
5OWW	Crystal structure of human BRD4(1) bromodomain in complex with UT22B 分子名称: Bromodomain-containing protein 4, ~{N}-(3-methylbenzotriazol-5-yl)-1-(phenylmethyl)imidazole-2-carboxamide 著者 Zhu, J, Caflisch, A. 登録日 2017-09-04 公開日 2018-10-10 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Chemical Space Expansion of Bromodomain Ligands Guided by in Silico Virtual Couplings (AutoCouple). Acs Cent.Sci., 4, 2018
7F5B	LBD-TMD focused reconstruction of DNQX-bound GluK2-1xNeto2 complex 分子名称: (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 He, L.L, Gao, Y.W, Li, B, Zhao, Y. 登録日 2021-06-21 公開日 2021-09-29 最終更新日 2021-12-01 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Kainate receptor modulation by NETO2. Nature, 599, 2021
7F5A	DNQX-bound GluK2-2xNeto2 complex 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, kainate 2, ... 著者 He, L.L, Gao, Y.W, Li, B, Zhao, Y. 登録日 2021-06-21 公開日 2021-09-29 最終更新日 2021-12-01 実験手法 ELECTRON MICROSCOPY (6.4 Å) 主引用文献 Kainate receptor modulation by NETO2. Nature, 599, 2021
7F57	Kainate-bound GluK2-1xNeto2 complex, at the desensitized state 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, kainate 2, ... 著者 He, L.L, Gao, Y.W, Li, B, Zhao, Y. 登録日 2021-06-21 公開日 2021-09-29 最終更新日 2021-12-01 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Kainate receptor modulation by NETO2. Nature, 599, 2021
5OVB	Crystal structure of human BRD4(1) bromodomain in complex with DR46 分子名称: Bromodomain-containing protein 4, ~{N}-[3-(5-ethanoyl-2-ethoxy-phenyl)-5-(1-methylpyrazol-3-yl)phenyl]furan-2-carboxamide 著者 Zhu, J, Caflisch, A. 登録日 2017-08-28 公開日 2018-10-10 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Chemical Space Expansion of Bromodomain Ligands Guided by in Silico Virtual Couplings (AutoCouple). Acs Cent.Sci., 4, 2018
3NZM	Crystal structure of DNAE intein with N-extein in redox trap 分子名称: DNA polymerase III subunit alpha, SULFATE ION 著者 Van Roey, P, Belfort, M, Callahan, B.P. 登録日 2010-07-16 公開日 2011-06-01 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Structure of catalytically competent intein caught in a redox trap with functional and evolutionary implications. Nat.Struct.Mol.Biol., 18, 2011
6MWN	Crystal structure of hepatitis A virus IRES domain V in complex with Fab HAVx 分子名称: Fab HAVx Heavy Chain, Fab HAVx Light Chain, HAV dV RNA (92-MER) 著者 Koirala, D, Shao, Y, Piccirilli, J.A. 登録日 2018-10-29 公開日 2019-08-14 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.838 Å) 主引用文献 A conserved RNA structural motif for organizing topology within picornaviral internal ribosome entry sites. Nat Commun, 10, 2019

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