5OWW

Crystal structure of human BRD4(1) bromodomain in complex with UT22B

Summary for 5OWW

DescriptorBromodomain-containing protein 4, ~{N}-(3-methylbenzotriazol-5-yl)-1-(phenylmethyl)imidazole-2-carboxamide (3 entities in total)
Functional Keywordsbrd4 bromodomain 1(brp4(1)), inhibitor, dna binding protein
Biological sourceHomo sapiens (Human)
Total number of polymer chains4
Total molecular weight61662.45
Authors
Zhu, J.,Caflisch, A. (deposition date: 2017-09-04, release date: 2018-10-10)
Primary citation
Zhu, J.,Caflisch, A.
Crystal structure of human BRD4(1) bromodomain in complex with UT22B
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.5 Å)
?

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.20330 0.2% 0.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 5oww
no rotation
Molmil generated image of 5oww
rotated about x axis by 90°
Molmil generated image of 5oww
rotated about y axis by 90°