4WVS
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![BU of 4wvs by Molmil](/molmil-images/mine/4wvs) | Crystal structure of XIAP-BIR2 domain complexed with (S)-3-(4-methoxyphenyl)-2-((S)-2-((S)-1-((S)-2-((S)-2-(methylamino)propanamido)pent-4-ynoyl)pyrrolidine-2-carboxamido)-3-phenylpropanamido)propanoic acid | 分子名称: | 3,11-DIFLUORO-6,8,13-TRIMETHYL-8H-QUINO[4,3,2-KL]ACRIDIN-13-IUM, E3 ubiquitin-protein ligase XIAP, GLYCEROL, ... | 著者 | Pokross, M.E. | 登録日 | 2014-11-07 | 公開日 | 2015-05-06 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | The Discovery of Macrocyclic XIAP Antagonists from a DNA-Programmed Chemistry Library, and Their Optimization To Give Lead Compounds with in Vivo Antitumor Activity. J.Med.Chem., 58, 2015
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6CG0
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![BU of 6cg0 by Molmil](/molmil-images/mine/6cg0) | Cryo-EM structure of mouse RAG1/2 HFC complex (3.17 A) | 分子名称: | CALCIUM ION, DNA (30-MER), DNA (41-MER), ... | 著者 | Chen, X, Kim, M, Chuenchor, W, Cui, Y, Zhang, X, Zhou, Z.H, Gellert, M, Yang, W. | 登録日 | 2018-02-19 | 公開日 | 2018-04-25 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.17 Å) | 主引用文献 | Cracking the DNA Code for V(D)J Recombination. Mol. Cell, 70, 2018
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4PPE
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![BU of 4ppe by Molmil](/molmil-images/mine/4ppe) | human RNF4 RING domain | 分子名称: | E3 ubiquitin-protein ligase RNF4, ZINC ION | 著者 | Perry, J.J, Arvai, A.S, Hitomi, C, Tainer, J.A. | 登録日 | 2014-02-26 | 公開日 | 2014-03-26 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | RNF4 interacts with both SUMO and nucleosomes to promote the DNA damage response. Embo Rep., 15, 2014
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2C2L
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![BU of 2c2l by Molmil](/molmil-images/mine/2c2l) | Crystal structure of the CHIP U-box E3 ubiquitin ligase | 分子名称: | CARBOXY TERMINUS OF HSP70-INTERACTING PROTEIN, HSP90, NICKEL (II) ION, ... | 著者 | Zhang, M, Roe, S.M, Pearl, L.H. | 登録日 | 2005-09-29 | 公開日 | 2005-11-23 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Chaperoned Ubiquitylation-Crystal Structures of the Chip U Box E3 Ubiquitin Ligase and a Chip-Ubc13-Uev1A Complex Mol.Cell, 20, 2005
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4QPL
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![BU of 4qpl by Molmil](/molmil-images/mine/4qpl) | Crystal structure of RNF146(RING-WWE)/UbcH5a/iso-ADPr complex | 分子名称: | 2'-O-(5-O-phosphono-alpha-D-ribofuranosyl)adenosine 5'-(dihydrogen phosphate), E3 ubiquitin-protein ligase RNF146, Ubiquitin-conjugating enzyme E2 D1, ... | 著者 | Wang, Z, DaRosa, P.A, Klevit, R.E, Xu, W. | 登録日 | 2014-06-23 | 公開日 | 2014-10-15 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Allosteric activation of the RNF146 ubiquitin ligase by a poly(ADP-ribosyl)ation signal. Nature, 517, 2015
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3RKY
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![BU of 3rky by Molmil](/molmil-images/mine/3rky) | |
2YBF
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![BU of 2ybf by Molmil](/molmil-images/mine/2ybf) | Complex of Rad18 (Rad6 binding domain) with Rad6b | 分子名称: | BETA-MERCAPTOETHANOL, E3 UBIQUITIN-PROTEIN LIGASE RAD18, SODIUM ION, ... | 著者 | Hibbert, R.G, Sixma, T.K. | 登録日 | 2011-03-08 | 公開日 | 2011-04-20 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | E3 Ligase Rad18 Promotes Monoubiquitination Rather Than Ubiquitin Chain Formation by E2 Enzyme Rad6. Proc.Natl.Acad.Sci.USA, 108, 2011
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5CKI
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![BU of 5cki by Molmil](/molmil-images/mine/5cki) | Crystal structure of 9DB1* deoxyribozyme (Cobalt hexammine soaked crystals) | 分子名称: | COBALT (II) ION, DNA (44-MER), MAGNESIUM ION, ... | 著者 | Ponce-Salvatierra, A, Hoebartner, C, Pena, V. | 登録日 | 2015-07-15 | 公開日 | 2016-01-13 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.985 Å) | 主引用文献 | Crystal structure of a DNA catalyst. Nature, 529, 2016
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3HQM
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![BU of 3hqm by Molmil](/molmil-images/mine/3hqm) | |
3HSV
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![BU of 3hsv by Molmil](/molmil-images/mine/3hsv) | Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases: SPOPMATHx-MacroH2ASBCpep2 | 分子名称: | Core histone macro-H2A.1, SULFATE ION, Speckle-type POZ protein, ... | 著者 | Zhuang, M, Schulman, B.A, Miller, D. | 登録日 | 2009-06-10 | 公開日 | 2009-10-20 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | 主引用文献 | Structures of SPOP-substrate complexes: insights into molecular architectures of BTB-Cul3 ubiquitin ligases. Mol.Cell, 36, 2009
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3RD2
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![BU of 3rd2 by Molmil](/molmil-images/mine/3rd2) | |
8HSV
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![BU of 8hsv by Molmil](/molmil-images/mine/8hsv) | The structure of rat beta-arrestin1 in complex with a rat Mdm2 peptide | 分子名称: | Beta-arrestin-1, SULFATE ION, peptide from E3 ubiquitin-protein ligase Mdm2 | 著者 | Yun, Y, Yoon, H.J, Choi, Y, Lee, H.H. | 登録日 | 2022-12-20 | 公開日 | 2023-07-19 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | GPCR targeting of E3 ubiquitin ligase MDM2 by inactive beta-arrestin. Proc.Natl.Acad.Sci.USA, 120, 2023
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3NTW
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![BU of 3ntw by Molmil](/molmil-images/mine/3ntw) | |
3RKX
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![BU of 3rkx by Molmil](/molmil-images/mine/3rkx) | |
3RKW
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![BU of 3rkw by Molmil](/molmil-images/mine/3rkw) | |
3GNB
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![BU of 3gnb by Molmil](/molmil-images/mine/3gnb) | Crystal structure of the RAG1 nonamer-binding domain with DNA | 分子名称: | 5'-D(*AP*AP*TP*TP*TP*TP*CP*AP*GP*AP*AP*AP*CP*C)-3', 5'-D(*AP*GP*GP*TP*TP*TP*CP*TP*GP*AP*AP*AP*AP*C)-3', V(D)J recombination-activating protein 1 | 著者 | Yin, F.F, Bailey, S, Innis, C.A, Steitz, T.A, Schatz, D.G. | 登録日 | 2009-03-16 | 公開日 | 2009-04-28 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structure of the RAG1 nonamer binding domain with DNA reveals a dimer that mediates DNA synapsis. Nat.Struct.Mol.Biol., 16, 2009
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3GNA
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![BU of 3gna by Molmil](/molmil-images/mine/3gna) | Crystal structure of the RAG1 nonamer-binding domain with DNA | 分子名称: | 5'-D(*AP*CP*TP*TP*AP*AP*CP*AP*AP*AP*AP*AP*CP*C)-3', 5'-D(*TP*GP*GP*TP*TP*TP*TP*TP*GP*TP*TP*AP*AP*G)-3', V(D)J recombination-activating protein 1 | 著者 | Yin, F.F, Bailey, S, Innis, C.A, Steitz, T.A, Schatz, D.G. | 登録日 | 2009-03-16 | 公開日 | 2009-04-28 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structure of the RAG1 nonamer binding domain with DNA reveals a dimer that mediates DNA synapsis. Nat.Struct.Mol.Biol., 16, 2009
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2K7F
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![BU of 2k7f by Molmil](/molmil-images/mine/2k7f) | HADDOCK calculated model of the complex between the BRCT region of RFC p140 and dsDNA | 分子名称: | 5'-D(P*DCP*DGP*DAP*DCP*DCP*DTP*DCP*DGP*DAP*DGP*DAP*DTP*DCP*DA)-3', 5'-D(P*DCP*DTP*DCP*DGP*DAP*DGP*DGP*DTP*DCP*DG)-3', Replication factor C subunit 1 | 著者 | Kobayashi, M, Ab, E, Bonvin, A, Siegal, G. | 登録日 | 2008-08-10 | 公開日 | 2009-09-08 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of the DNA-bound BRCA1 C-terminal region from human replication factor C p140 and model of the protein-DNA complex. J.Biol.Chem., 285, 2010
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3FL2
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![BU of 3fl2 by Molmil](/molmil-images/mine/3fl2) | Crystal structure of the ring domain of the E3 ubiquitin-protein ligase UHRF1 | 分子名称: | E3 ubiquitin-protein ligase UHRF1, ZINC ION | 著者 | Walker, J.R, Avvakumov, G.V, Xue, S, Li, Y, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | 登録日 | 2008-12-18 | 公開日 | 2009-01-20 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structure of the Ring Domain of the E3 Ubiquitin-Protein Ligase Uhrf1 To be Published
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3SQI
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![BU of 3sqi by Molmil](/molmil-images/mine/3sqi) | DNA binding domain of Ndc10 | 分子名称: | DNA (5'-D(P*AP*AP*AP*TP*TP*TP*TP*AP*TP*AP*AP*AP*TP*TP*A)-3'), DNA (5'-D(P*TP*TP*AP*AP*TP*TP*TP*AP*TP*AP*AP*AP*AP*TP*T)-3'), KLLA0E03807p | 著者 | Cho, U.S, Harrison, S.C. | 登録日 | 2011-07-05 | 公開日 | 2011-12-07 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.8245 Å) | 主引用文献 | Ndc10 is a platform for inner kinetochore assembly in budding yeast. Nat.Struct.Mol.Biol., 19, 2011
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2MRE
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![BU of 2mre by Molmil](/molmil-images/mine/2mre) | NMR structure of the Rad18-UBZ/ubiquitin complex | 分子名称: | E3 ubiquitin-protein ligase RAD18, Polyubiquitin-C, ZINC ION | 著者 | Rizzo, A.A, Salerno, P.E, Bezsonova, I, Korzhnev, D.M. | 登録日 | 2014-07-03 | 公開日 | 2014-10-22 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR Structure of the Human Rad18 Zinc Finger in Complex with Ubiquitin Defines a Class of UBZ Domains in Proteins Linked to the DNA Damage Response. Biochemistry, 53, 2014
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6IIW
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![BU of 6iiw by Molmil](/molmil-images/mine/6iiw) | |
6BRQ
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![BU of 6brq by Molmil](/molmil-images/mine/6brq) | Crystal structure of rice ASK1-D3 ubiquitin ligase complex crystal form 3 | 分子名称: | F-box/LRR-repeat MAX2 homolog, SKP1-like protein 1A | 著者 | Shabek, N, Zheng, N, Mao, H, Hinds, T.R, Ticchiarelli, F, Leyser, O. | 登録日 | 2017-11-30 | 公開日 | 2018-11-21 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.99 Å) | 主引用文献 | Structural plasticity of D3-D14 ubiquitin ligase in strigolactone signalling. Nature, 563, 2018
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6BRO
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4K95
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![BU of 4k95 by Molmil](/molmil-images/mine/4k95) | Crystal Structure of Parkin | 分子名称: | E3 ubiquitin-protein ligase parkin, ZINC ION | 著者 | Seirafi, M, Menade, M, Sauve, V, Kozlov, G, Trempe, J.-F, Nagar, B, Gehring, K. | 登録日 | 2013-04-19 | 公開日 | 2013-05-15 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (6.499 Å) | 主引用文献 | Structure of parkin reveals mechanisms for ubiquitin ligase activation. Science, 340, 2013
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