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3FL2

Crystal structure of the ring domain of the E3 ubiquitin-protein ligase UHRF1

Summary for 3FL2
Entry DOI10.2210/pdb3fl2/pdb
Related2FAZ 3BI7 3CLZ 3DB3 3DB4
DescriptorE3 ubiquitin-protein ligase UHRF1, ZINC ION (3 entities in total)
Functional Keywordscell cycle, dna damage, dna repair, ring finger domain, ligase, metal binding, dna replication, transcriptional silencing, chromatin, phosphorylation, transcription, transcription regulation, ubl conjugation, ubl conjugation pathway, zinc, zinc-finger, epigenetics, structural genomics, structural genomics consortium, sgc
Biological sourceHomo sapiens (human)
Cellular locationNucleus : Q96T88
Total number of polymer chains1
Total formula weight14133.73
Authors
Primary citationWalker, J.R.,Avvakumov, G.V.,Xue, S.,Li, Y.,Bountra, C.,Weigelt, J.,Arrowsmith, C.H.,Edwards, A.M.,Bochkarev, A.,Dhe-Paganon, S.
Structure of the Ring Domain of the E3 Ubiquitin-Protein Ligase Uhrf1
To be Published,
Experimental method
X-RAY DIFFRACTION (1.75 Å)
Structure validation

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PDB entries from 2024-03-27

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