3FL2
Crystal structure of the ring domain of the E3 ubiquitin-protein ligase UHRF1
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A1001 |
| Chain | Residue |
| A | CYS724 |
| A | CYS727 |
| A | CYS744 |
| A | CYS747 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A1002 |
| Chain | Residue |
| A | CYS739 |
| A | HIS741 |
| A | CYS759 |
| A | CYS762 |
Functional Information from PROSITE/UniProt
| site_id | PS00518 |
| Number of Residues | 10 |
| Details | ZF_RING_1 Zinc finger RING-type signature. CqHnVCkdCL |
| Chain | Residue | Details |
| A | CYS739-LEU748 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 39 |
| Details | Zinc finger: {"description":"RING-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00175","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"DEC-2008","submissionDatabase":"PDB data bank","title":"Structure of the Ring domain of the E3 ubiquitin-protein ligase Uhrf1.","authors":["Walker J.R.","Avvakumov G.V.","Xue S.","Li Y.","Bountra C.","Weigelt J.","Arrowsmith C.H.","Edwards A.M.","Bochkarev A.","Dhe-Paganon S."]}},{"source":"PDB","id":"3FL2","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
