2MRE

NMR structure of the Rad18-UBZ/ubiquitin complex

Summary for 2MRE

• Entry DOI: 10.2210/pdb2mre/pdb
• NMR Information: BMRB: 25070
• Descriptor: Polyubiquitin-C, E3 ubiquitin-protein ligase RAD18, ZINC ION (3 entities in total)
• Functional Keywords: protein complex, ligase-translation complex, replication-signaling protein complex, replication/signaling protein
• Biological source: Homo sapiens (human); More
• Cellular location: Ubiquitin: Cytoplasm : P0CG48; Nucleus : Q9NS91
• Total number of polymer chains: 2
• Total formula weight: 12552.64

Authors

Rizzo, A.A.,Salerno, P.E.,Bezsonova, I.,Korzhnev, D.M. (deposition date: 2014-07-03, release date: 2014-10-22, Last modification date: 2014-10-29)

• Primary citation: Rizzo, A.A.,Salerno, P.E.,Bezsonova, I.,Korzhnev, D.M.; NMR Structure of the Human Rad18 Zinc Finger in Complex with Ubiquitin Defines a Class of UBZ Domains in Proteins Linked to the DNA Damage Response.; Biochemistry, 53:5895-5906, 2014; PubMed: 25162118; DOI: 10.1021/bi500823h

Experimental method

SOLUTION NMR