5X28
 
 | | Crystal structure of EGFR 696-1022 L858R in complex with SKLB(6) | | 分子名称: | 9-cyclohexyl-N2-[4-(4-methylpiperazin-1-yl)phenyl]-N8-phenyl-purine-2,8-diamine, CHLORIDE ION, Epidermal growth factor receptor | | 著者 | Yun, C.H. | | 登録日 | 2017-01-31 | | 公開日 | 2018-02-07 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.952 Å) | | 主引用文献 | Structural insights into drug development strategy targeting EGFR T790M/C797S.
Oncotarget, 9, 2018
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5X2C
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5X2F
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5X2A
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1IZ4
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1I6H
 | | RNA POLYMERASE II ELONGATION COMPLEX | | 分子名称: | 5'-D(P*AP*AP*AP*TP*GP*CP*CP*TP*GP*GP*TP*CP*T)-3', 5'-R(P*GP*AP*CP*CP*AP*GP*GP*CP*A)-3', DNA-DIRECTED RNA POLYMERASE II 13.6KD POLYPEPTIDE, ... | | 著者 | Gnatt, A.L, Cramer, P, Kornberg, R.D. | | 登録日 | 2001-03-02 | | 公開日 | 2001-04-23 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Structural basis of transcription: an RNA polymerase II elongation complex at 3.3 A resolution.
Science, 292, 2001
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1IZ5
 | | Pyrococcus furiosus PCNA mutant (Met73Leu, Asp143Ala, Asp147Ala): orthorhombic form | | 分子名称: | Proliferating cell nuclear antigen | | 著者 | Matsumiya, S, Ishino, S, Ishino, Y, Morikawa, K. | | 登録日 | 2002-09-23 | | 公開日 | 2003-04-01 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Intermolecular ion pairs maintain the toroidal structure of Pyrococcus furiosus PCNA
PROTEIN SCI., 12, 2003
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1QJD
 | | Flavocytochrome C3 from Shewanella frigidimarina | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, FLAVOCYTOCHROME C3, GLYCEROL, ... | | 著者 | Taylor, P, Pealing, S.L, Reid, G.A, Chapman, S.K, Walkinshaw, M.D. | | 登録日 | 1999-06-23 | | 公開日 | 1999-11-21 | | 最終更新日 | 2019-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural and Mechanistic Mapping of a Unique Fumarate Reductase
Nat.Struct.Biol., 6, 1999
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2CH4
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2CH7
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3E0D
 | | Insights into the Replisome from the Crystral Structure of the Ternary Complex of the Eubacterial DNA Polymerase III alpha-subunit | | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase III subunit alpha, ... | | 著者 | Wing, R.A, Bailey, S, Steitz, T.A. | | 登録日 | 2008-07-31 | | 公開日 | 2008-09-23 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (4.6 Å) | | 主引用文献 | Insights into the Replisome from the Structure of a Ternary Complex of the DNA Polymerase III alpha-Subunit.
J.Mol.Biol., 382, 2008
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3DL8
 | | Structure of the complex of aquifex aeolicus SecYEG and bacillus subtilis SecA | | 分子名称: | Preprotein translocase subunit secY, Protein translocase subunit secA, Protein-export membrane protein secG, ... | | 著者 | Nam, Y, Zimmer, J, Rapoport, T.A. | | 登録日 | 2008-06-26 | | 公開日 | 2008-12-02 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (7.5 Å) | | 主引用文献 | Structure of a complex of the ATPase SecA and the protein-translocation channel.
Nature, 455, 2008
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3DIN
 | | Crystal structure of the protein-translocation complex formed by the SecY channel and the SecA ATPase | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ... | | 著者 | Zimmer, J, Nam, Y, Rapoport, T.A. | | 登録日 | 2008-06-20 | | 公開日 | 2008-10-07 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (4.5 Å) | | 主引用文献 | Structure of a complex of the ATPase SecA and the protein-translocation channel.
Nature, 455, 2008
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5WTA
 | | Crystal Structure of Staphylococcus aureus SdrE apo form | | 分子名称: | Serine-aspartate repeat-containing protein E | | 著者 | Wu, M, Zhang, Y, Hang, T, Wang, C, Yang, Y, Zang, J, Zhang, M, Zhang, X. | | 登録日 | 2016-12-10 | | 公開日 | 2017-07-19 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Staphylococcus aureus SdrE captures complement factor H's C-terminus via a novel 'close, dock, lock and latch' mechanism for complement evasion
Biochem. J., 474, 2017
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4V50
 | | Crystal Structure of Ribosome with messenger RNA and the Anticodon stem-loop of P-site tRNA. | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Berk, V, Zhang, W, Pai, R.D, Cate, J.H.D. | | 登録日 | 2006-08-16 | | 公開日 | 2014-07-09 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3.22 Å) | | 主引用文献 | Structural basis for mRNA and tRNA positioning on the ribosome.
Proc.Natl.Acad.Sci.Usa, 103, 2006
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2FO0
 | | Organization of the SH3-SH2 Unit in Active and Inactive Forms of the c-Abl Tyrosine Kinase | | 分子名称: | 6-(2,6-DICHLOROPHENYL)-2-{[3-(HYDROXYMETHYL)PHENYL]AMINO}-8-METHYLPYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE, GLYCEROL, MYRISTIC ACID, ... | | 著者 | Nagar, B, Hantschel, O, Seeliger, M, Davies, J.M, Weis, W.I, Superti-Furga, G, Kuriyan, J. | | 登録日 | 2006-01-12 | | 公開日 | 2006-03-21 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | | 主引用文献 | Organization of the SH3-SH2 unit in active and inactive forms of the c-Abl tyrosine kinase.
Mol.Cell, 21, 2006
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1UL1
 | | Crystal structure of the human FEN1-PCNA complex | | 分子名称: | Flap endonuclease-1, MAGNESIUM ION, Proliferating cell nuclear antigen | | 著者 | Sakurai, S, Kitano, K, Yamaguchi, H, Hamada, K, Okada, K, Fukuda, K, Uchida, M, Ohtsuka, E, Morioka, H, Hakoshima, T. | | 登録日 | 2003-09-05 | | 公開日 | 2005-03-01 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structural basis for recruitment of human flap endonuclease 1 to PCNA
EMBO J., 24, 2005
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6KLW
 | | Complex structure of Iota toxin enzymatic component (Ia) and binding component (Ib) pore with long stem | | 分子名称: | CALCIUM ION, Iota toxin component Ia, Iota toxin component Ib | | 著者 | Yoshida, T, Yamada, T, Kawamoto, A, Mitsuoka, K, Iwasaki, K, Tsuge, H. | | 登録日 | 2019-07-30 | | 公開日 | 2020-01-15 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Cryo-EM structures reveal translocational unfolding in the clostridial binary iota toxin complex.
Nat.Struct.Mol.Biol., 27, 2020
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6KLX
 | | Pore structure of Iota toxin binding component (Ib) | | 分子名称: | CALCIUM ION, Iota toxin component Ib | | 著者 | Yoshida, T, Yamada, T, Kawamoto, A, Mitsuoka, K, Iwasaki, K, Tsuge, H. | | 登録日 | 2019-07-30 | | 公開日 | 2020-01-15 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Cryo-EM structures reveal translocational unfolding in the clostridial binary iota toxin complex.
Nat.Struct.Mol.Biol., 27, 2020
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5FLM
 | | Structure of transcribing mammalian RNA polymerase II | | 分子名称: | DNA, DNA-RNA ELONGATION SCAFFOLD, DNA-DIRECTED RNA POLYMERASE, ... | | 著者 | Bernecky, C, Herzog, F, Baumeister, W, Plitzko, J.M, Cramer, P. | | 登録日 | 2015-10-26 | | 公開日 | 2016-01-20 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structure of Transcribing Mammalian RNA Polymerase II
Nature, 529, 2016
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6B8N
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6B8M
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6B8Q
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6B8P
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6B8L
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