PDB: 5653 件ウェブページステータス検索Chemie searchBIRD

---

8PKA	Structure of the human mitochondrial iron-sulfur cluster biosynthesis complex during persulfide transfer (without frataxin) 分子名称: Acyl carrier protein, Cysteine desulfurase, FE (II) ION, ... 著者 Steinhilper, R, Murphy, B.J. 登録日 2023-06-26 公開日 2024-05-01 実験手法 ELECTRON MICROSCOPY (2.75 Å) 主引用文献 Mechanism and structural dynamics of sulfur transfer during de novo [2Fe-2S] cluster assembly on ISCU2. Nat Commun, 15, 2024
8PK9	Structure of the human mitochondrial iron-sulfur cluster biosynthesis complex during persulfide transfer (persulfide on NFS1 and ISCU2) 分子名称: Acyl carrier protein, Cysteine desulfurase, FE (II) ION, ... 著者 Steinhilper, R, Murphy, B.J. 登録日 2023-06-26 公開日 2024-05-01 実験手法 ELECTRON MICROSCOPY (2.58 Å) 主引用文献 Mechanism and structural dynamics of sulfur transfer during de novo [2Fe-2S] cluster assembly on ISCU2. Nat Commun, 15, 2024
8JMN	Cryo-EM structure of the gastric proton pump with bound DQ-21 分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1-[4-[[2-[(4-chlorophenyl)methoxy]phenyl]methoxy]phenyl]-N-methyl-methanamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Abe, K, Yokoshima, S, Yoshimori, A. 登録日 2023-06-05 公開日 2023-08-30 最終更新日 2023-10-04 実験手法 ELECTRON MICROSCOPY (2.26 Å) 主引用文献 Deep learning driven de novo drug design based on gastric proton pump structures. Commun Biol, 6, 2023
6F57	Crystal structure of DNMT3A-DNMT3L in complex with single CpG-containing DNA 分子名称: DNA (5'-D(*AP*GP*AP*GP*CP*GP*CP*AP*TP*G)-3'), DNA (5'-D(*CP*AP*TP*GP*ZP*GP*CP*TP*CP*T)-3'), DNA (cytosine-5)-methyltransferase 3-like, ... 著者 Zhang, Z.M, Song, J. 登録日 2017-12-01 公開日 2018-01-31 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.098 Å) 主引用文献 Structural basis for DNMT3A-mediated de novo DNA methylation. Nature, 554, 2018
8JSM	The structure of EBOV L-VP35-RNA complex (conformation 1) 分子名称: Polymerase cofactor VP35, RNA-directed RNA polymerase L, The leader sequence of EBOV genome., ... 著者 Qi, P, Yi, S. 登録日 2023-06-20 公開日 2023-09-27 最終更新日 2023-11-01 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Molecular mechanism of de novo replication by the Ebola virus polymerase. Nature, 622, 2023
8JSL	The structure of EBOV L-VP35-RNA complex 分子名称: Polymerase cofactor VP35, RNA-directed RNA polymerase L, The leader sequence of EBOV, ... 著者 Qi, P, Yi, S. 登録日 2023-06-20 公開日 2023-09-27 最終更新日 2023-11-01 実験手法 ELECTRON MICROSCOPY (2.95 Å) 主引用文献 Molecular mechanism of de novo replication by the Ebola virus polymerase. Nature, 622, 2023
5NNL	Inactive dihydroorotase-like domain of Chaetomium thermophilum CAD-like multifunctional protein 分子名称: Inactive dihydroorotase-like domain 著者 Ramon-Maiques, S, Moreno-Morcillo, M, Grande-Garcia, A. 登録日 2017-04-10 公開日 2017-06-07 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.13 Å) 主引用文献 Structural Insight into the Core of CAD, the Multifunctional Protein Leading De Novo Pyrimidine Biosynthesis. Structure, 25, 2017
8JSN	The structure of EBOV L-VP35-RNA complex (conformation 2) 分子名称: Polymerase cofactor VP35, RNA-directed RNA polymerase L, The leader sequence of EBOV genome, ... 著者 Qi, P, Yi, S. 登録日 2023-06-20 公開日 2023-09-27 最終更新日 2023-11-01 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Molecular mechanism of de novo replication by the Ebola virus polymerase. Nature, 622, 2023
5D9B	Luciferin-regenerating enzyme solved by SIRAS using XFEL (refined against native data) 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Luciferin regenerating enzyme, MAGNESIUM ION 著者 Yamashita, K, Pan, D, Okuda, T, Murai, T, Kodan, A, Yamaguchi, T, Gomi, K, Kajiyama, N, Kato, H, Ago, H, Yamamoto, M, Nakatsu, T. 登録日 2015-08-18 公開日 2015-09-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 An isomorphous replacement method for efficient de novo phasing for serial femtosecond crystallography. Sci Rep, 5, 2015
5D9D	Luciferin-regenerating enzyme solved by SAD using synchrotron radiation at room temperature 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Luciferin regenerating enzyme, MAGNESIUM ION, ... 著者 Yamashita, K, Pan, D, Okuda, T, Murai, T, Kodan, A, Yamaguchi, T, Gomi, K, Kajiyama, N, Kato, H, Ago, H, Yamamoto, M, Nakatsu, T. 登録日 2015-08-18 公開日 2015-09-23 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.701 Å) 主引用文献 An isomorphous replacement method for efficient de novo phasing for serial femtosecond crystallography. Sci Rep, 5, 2015
5D9C	Luciferin-regenerating enzyme solved by SIRAS using XFEL (refined against Hg derivative data) 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Luciferin regenerating enzyme, MAGNESIUM ION, ... 著者 Yamashita, K, Pan, D, Okuda, T, Murai, T, Kodan, A, Yamaguchi, T, Gomi, K, Kajiyama, N, Kato, H, Ago, H, Yamamoto, M, Nakatsu, T. 登録日 2015-08-18 公開日 2015-09-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 An isomorphous replacement method for efficient de novo phasing for serial femtosecond crystallography. Sci Rep, 5, 2015
6BRR	Crystal structure of DNMT3A (R836A)-DNMT3L in complex with DNA containing two CpG sites 分子名称: DNA (25-MER), DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3A, ... 著者 Zhang, Z.M, Song, J. 登録日 2017-11-30 公開日 2018-01-31 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.97 Å) 主引用文献 Structural basis for DNMT3A-mediated de novo DNA methylation. Nature, 554, 2018
4C11	Dengue virus RNA dependent RNA polymerase with residues from the NS5 linker region 分子名称: DENGUE VIRUS TYPE 3 RNA DEPENDENT RNA POLYMERASE, ZINC ION 著者 Lim, S.P, Lescar, J. 登録日 2013-08-09 公開日 2013-08-21 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 A Crystal Structure of the Dengue Virus Ns5 Polymerase Delineates Inter-Domain Amino Acids Residues that Enhance its Thermostability and De Novo Initiation Activities. J.Biol.Chem., 288, 2013
1U0I	IAAL-E3/K3 heterodimer 分子名称: IAAL-E3, IAAL-K3 著者 Lindhout, D.A, Litowski, J.R, Mercier, P, Hodges, R.S, Sykes, B.D. 登録日 2004-07-13 公開日 2004-10-19 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 NMR solution structure of a highly stable de novo heterodimeric coiled-coil Biopolymers, 75, 2004
5K7F	Crystal structure of apo AibR 分子名称: ACETATE ION, Transcriptional regulator, TetR family 著者 Bock, T, Volz, C, Mueller, R, Blankenfeldt, W. 登録日 2016-05-26 公開日 2016-12-21 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 The AibR-isovaleryl coenzyme A regulator and its DNA binding site - a model for the regulation of alternative de novo isovaleryl coenzyme A biosynthesis in Myxococcus xanthus. Nucleic Acids Res., 45, 2017
5CIY	Structural basis of the recognition of H3K36me3 by DNMT3B PWWP domain 分子名称: DNA (5'-D(P*CP*CP*AP*TP*GP*CP*GP*CP*TP*GP*AP*C)-3'), DNA (5'-D(P*GP*TP*CP*AP*GP*(3DR)P*GP*CP*AP*TP*GP*G)-3'), Modification methylase HhaI, ... 著者 Rondelet, G, DAL MASO, T, Willems, L, Wouters, J. 登録日 2015-07-13 公開日 2016-03-30 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.594 Å) 主引用文献 Structural basis for recognition of histone H3K36me3 nucleosome by human de novo DNA methyltransferases 3A and 3B. J.Struct.Biol., 194, 2016
5K7H	Crystal structure of AibR in complex with the effector molecule isovaleryl coenzyme A 分子名称: CHLORIDE ION, Isovaleryl-coenzyme A, NICKEL (II) ION, ... 著者 Bock, T, Volz, C, Mueller, R, Blankenfeldt, W. 登録日 2016-05-26 公開日 2016-12-21 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 The AibR-isovaleryl coenzyme A regulator and its DNA binding site - a model for the regulation of alternative de novo isovaleryl coenzyme A biosynthesis in Myxococcus xanthus. Nucleic Acids Res., 45, 2017
5CIU	Structural basis of the recognition of H3K36me3 by DNMT3B PWWP domain 分子名称: DNA (cytosine-5)-methyltransferase 3B, GLYCEROL, Histone H3.2 著者 Rondelet, G, DAL MASO, T, Willems, L, Wouters, J. 登録日 2015-07-13 公開日 2016-03-30 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.24 Å) 主引用文献 Structural basis for recognition of histone H3K36me3 nucleosome by human de novo DNA methyltransferases 3A and 3B. J.Struct.Biol., 194, 2016
5KEZ	Selective and potent inhibition of the glycosidase human amylase by the short and extremely compact peptide piHA from mRNA display 分子名称: ACE-DTY-PRO-TYR-SER-CYS-TRP-VAL-ARG-HIS-NH2, CALCIUM ION, CHLORIDE ION, ... 著者 Caner, S, Brayer, G.D. 登録日 2016-06-10 公開日 2017-03-29 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 Rapid Discovery of Potent and Selective Glycosidase-Inhibiting De Novo Peptides. Cell Chem Biol, 24, 2017
6U8X	Crystal structure of DNMT3B-DNMT3L in complex with CpApG DNA 分子名称: CpApG DNA (25-MER), DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3B, ... 著者 Gao, L, Song, J. 登録日 2019-09-06 公開日 2020-06-10 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.95063877 Å) 主引用文献 Comprehensive structure-function characterization of DNMT3B and DNMT3A reveals distinctive de novo DNA methylation mechanisms. Nat Commun, 11, 2020
5JD2	SFX structure of corestreptavidin-selenobiotin complex 分子名称: 5-[(3aS,4S,6aR)-2-oxohexahydro-1H-selenopheno[3,4-d]imidazol-4-yl]pentanoic acid, Streptavidin 著者 DeMirci, H, Hunter, M.S, Boutet, S. 登録日 2016-04-15 公開日 2016-11-16 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Selenium single-wavelength anomalous diffraction de novo phasing using an X-ray-free electron laser. Nat Commun, 7, 2016
4ONJ	Crystal structure of the catalytic domain of ntDRM 分子名称: DNA methyltransferase, SINEFUNGIN 著者 Du, J, Patel, D.J. 登録日 2014-01-28 公開日 2014-06-04 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.807 Å) 主引用文献 Molecular Mechanism of Action of Plant DRM De Novo DNA Methyltransferases. Cell(Cambridge,Mass.), 157, 2014
6U8P	Crystal structure of DNMT3B-DNMT3L in complex with CpGpA DNA 分子名称: CpGpA DNA (25-MER), DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3B, ... 著者 Gao, L, Song, J. 登録日 2019-09-05 公開日 2020-06-10 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.05 Å) 主引用文献 Comprehensive structure-function characterization of DNMT3B and DNMT3A reveals distinctive de novo DNA methylation mechanisms. Nat Commun, 11, 2020
6U8V	Crystal structure of DNMT3B-DNMT3L in complex with CpGpT DNA 分子名称: CpGpT DNA (25-MER), DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3B, ... 著者 Gao, L, Zhang, Z.M, Song, J. 登録日 2019-09-06 公開日 2020-06-10 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Comprehensive structure-function characterization of DNMT3B and DNMT3A reveals distinctive de novo DNA methylation mechanisms. Nat Commun, 11, 2020
4ONQ	Crystal structure of ntDRM E283S/R309S/F310S/Y590S/D591S mutant 分子名称: DNA methyltransferase, SINEFUNGIN 著者 Du, J, Patel, D.J. 登録日 2014-01-28 公開日 2014-06-04 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.502 Å) 主引用文献 Molecular Mechanism of Action of Plant DRM De Novo DNA Methyltransferases. Cell(Cambridge,Mass.), 157, 2014

<18192021222324252627282930313233>