4C11

Dengue virus RNA dependent RNA polymerase with residues from the NS5 linker region

Summary for 4C11

Entry DOI	10.2210/pdb4c11/pdb
Descriptor	DENGUE VIRUS TYPE 3 RNA DEPENDENT RNA POLYMERASE, ZINC ION, ... (4 entities in total)
Functional Keywords	transferase, rna dependent rna polymerase
Biological source	DENGUE VIRUS More
Total number of polymer chains	2
Total formula weight	148206.01
Authors	Lim, S.P.,Lescar, J. (deposition date: 2013-08-09, release date: 2013-08-21, Last modification date: 2018-04-04)
Primary citation	Lim, S.P.,Koh, J.H.K.,Seh, C.C.,Liew, C.W.,Davidson, A.D.,Chua, L.S.,Chandrasekaran, R.,Cornvik, T.C.,Shi, P.,Lescar, J. A Crystal Structure of the Dengue Virus Ns5 Polymerase Delineates Inter-Domain Amino Acids Residues that Enhance its Thermostability and De Novo Initiation Activities. J.Biol.Chem., 288:31105-, 2013 Cited by PubMed: 24025331 DOI: 10.1074/JBC.M113.508606 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation