PDB: 97138 件ウェブページステータス検索Chemie searchBIRD

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1SII	AGAO in covalent complex with the inhibitor NOBA ("4-(2-naphthyloxy)-2-butyn-1-amine") 分子名称: COPPER (II) ION, GLYCEROL, Phenylethylamine oxidase, ... 著者 Guss, J.M, Langley, D.B, Duff, A.P. 登録日 2004-02-29 公開日 2004-09-07 最終更新日 2017-10-11 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Differential Inhibition of Six Copper Amine Oxidases by a Family of 4-(Aryloxy)-2-butynamines: Evidence for a New Mode of Inactivation. Biochemistry, 43, 2004
1SIH	AGAO in covalent complex with the inhibitor MOBA ("4-(4-methylphenoxy)-2-butyn-1-amine") 分子名称: COPPER (II) ION, GLYCEROL, Phenylethylamine oxidase, ... 著者 Guss, J.M, Langley, D.B, Duff, A.P. 登録日 2004-02-29 公開日 2004-09-07 最終更新日 2017-10-11 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 Differential Inhibition of Six Copper Amine Oxidases by a Family of 4-(Aryloxy)-2-butynamines: Evidence for a New Mode of Inactivation. Biochemistry, 43, 2004
3TN2	structure analysis of MIP1-beta P8A 分子名称: C-C motif chemokine 4, ZINC ION 著者 Guo, Q, Tang, W.J. 登録日 2011-09-01 公開日 2012-09-05 最終更新日 2018-08-22 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structures of human CCL18, CCL3, and CCL4 reveal molecular determinants for quaternary structures and sensitivity to insulin-degrading enzyme. J.Mol.Biol., 427, 2015
1A75	WHITING PARVALBUMIN 分子名称: CALCIUM ION, PARVALBUMIN 著者 Declercq, J.P, Baneres, J.L, Rambaud, J, Parello, J. 登録日 1998-03-19 公開日 1998-06-17 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Tertiary Structure of a Trp-Containing Parvalbumin from Whiting (Merlangius Merlangus). Description of the Hydrophobic Core To be Published
1J1A	PANCREATIC SECRETORY PHOSPHOLIPASE A2 (IIa) WITH ANTI-INFLAMMATORY ACTIVITY 分子名称: (S)-5-(4-BENZYLOXY-PHENYL)-4-(7-PHENYL-HEPTANOYLAMINO)-PENTANOIC ACID, CALCIUM ION, Phospholipase A2 著者 Hansford, K.A, Reid, R.C, Clark, C.I, Tyndall, J.D.A, Whitehouse, M.W, Guthrie, T, McGeary, R.P, Schafer, K, Martin, J.L, Fairlie, D.P. 登録日 2002-12-03 公開日 2003-03-18 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 D-Tyrosine as a Chiral Precusor to Potent Inhibitors of Human Nonpancreatic Secretory Phospholipase A2 (IIa) with Antiinflammatory Activity Chembiochem, 4, 2003
4AN7	Kunitz type trypsin inhibitor complex with porcine trypsin 分子名称: CALCIUM ION, TRYPSIN, TRYPSIN INHIBITOR 著者 Patil, D.N, Chaudhary, A, Kumar, P. 登録日 2012-03-15 公開日 2012-11-07 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.23 Å) 主引用文献 Structural Basis for Dual Inhibitory Role of Tamarind Kunitz Inhibitor (Tki) Against Factor Xa and Trypsin. FEBS J., 279, 2012
4AC3	S.pneumoniae GlmU in complex with an antibacterial inhibitor 分子名称: BIFUNCTIONAL PROTEIN GLMU, N-{2,4-DIMETHOXY-5-[(2-PIPERIDIN-1-YLBENZYL)sulfamoyl]phenyl}acetamide, SULFATE ION 著者 Otterbein, L, Breed, J, Ogg, D.J. 登録日 2011-12-12 公開日 2012-02-15 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Inhibitors of Acetyltransferase Domain of N-Acetylglucosamine-1-Phosphate-Uridyltransferase/ Glucosamine-1-Phosphate-Acetyltransferase (Glmu). Part 1: Hit to Lead Evaluation of a Novel Arylsulfonamide Series. Bioorg.Med.Chem.Lett., 22, 2012
4NL0	Structural and functional characterization of a novel Alpha Kinase in complex with ADP from Entamoeba histolytica 分子名称: ADENOSINE-5'-DIPHOSPHATE, Protein kinase, putative, ... 著者 Tarique, K.F, Rehman, S.A.A, Bhattacharya, A, Gourinath, S, Mansuri, M.S. 登録日 2013-11-13 公開日 2014-11-19 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.41 Å) 主引用文献 Structural and functional characterization of a novel Alpha Kinase in complex with ADP from Entamoeba histolytica To be Published
4BEZ	Night blindness causing G90D rhodopsin in the active conformation 分子名称: ACETATE ION, PALMITIC ACID, RHODOPSIN, ... 著者 Singhal, A, Ostermaier, M.K, Vishnivetskiy, S.A, Panneels, V, Homan, K.T, Tesmer, J.J.G, Veprintsev, D, Deupi, X, Gurevich, V.V, Schertler, G.F.X, Standfuss, J. 登録日 2013-03-12 公開日 2013-04-24 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Insights Into Congenital Stationary Night Blindness Based on the Structure of G90D Rhodopsin. Embo Rep., 14, 2013
4ORK	Crystal Structure of the Phosphotransferase Domain of the Bifunctional Aminoglycoside Resistance Enzyme AAC(6')-Ie-APH(2'')-Ia 分子名称: Bifunctional AAC/APH, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION 著者 Smith, C.A, Toth, M, Bhattacharya, M, Frase, H, Vakulenko, S.B. 登録日 2014-02-11 公開日 2014-07-02 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure of the phosphotransferase domain of the bifunctional aminoglycoside-resistance enzyme AAC(6')-Ie-APH(2'')-Ia. Acta Crystallogr.,Sect.D, 70, 2014
3P89	FXR bound to a quinolinecarboxylic acid 分子名称: 6-(4-{[3-(2,6-dichlorophenyl)-5-(1-methylethyl)isoxazol-4-yl]methoxy}phenyl)quinoline-2-carboxylic acid, Farnesoid X receptor, Nuclear receptor coactivator 1, ... 著者 Madauss, K.P, Williams, S.P, Deaton, D.N. 登録日 2010-10-13 公開日 2011-08-31 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Conformationally constrained farnesoid X receptor (FXR) agonists: Heteroaryl replacements of the naphthalene. Bioorg.Med.Chem.Lett., 21, 2011
2QMV	High Resolution Structure of Peroxisone Proliferation-Activated Receptor gamma and Characterisation of its Interaction with the Co-activator Transcriptional Intermediary Factor 2 分子名称: Peroxisome proliferator-activated receptor gamma 著者 Hartl, R, Riepl, H, Kauschke, S, Kalbitzer, H.R, Maurer, T. 登録日 2007-07-17 公開日 2008-09-02 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 High Resolution Structure of Peroxisone Proliferation-Activated Receptor gamma and Characterisation of its Interaction with the Co-activator Transcriptional Intermediary Factor 2 To be Published
4O6K	The crystal structure of zebrafish IL-22 分子名称: Interleukin 22 著者 Siupka, P, Hamming, O.J, Fretaud, M, Luftalla, G, Levraud, J.P, Hartmann, R. 登録日 2013-12-21 公開日 2014-09-10 最終更新日 2018-05-23 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The crystal structure of zebrafish IL-22 reveals an evolutionary, conserved structure highly similar to that of human IL-22. Genes Immun., 15, 2014
4OMT	Crystal structure of human muscle phosphofructokinase (dissociated homodimer) 分子名称: 6-phosphofructokinase, muscle type 著者 Kloos, M, Straeter, N. 登録日 2014-01-27 公開日 2014-05-14 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (6 Å) 主引用文献 Crystallization and preliminary crystallographic analysis of human muscle phosphofructokinase, the main regulator of glycolysis. Acta Crystallogr F Struct Biol Commun, 70, 2014
3P88	FXR bound to isoquinolinecarboxylic acid 分子名称: 7-(4-{[3-(2,6-dimethylphenyl)-5-(1-methylethyl)isoxazol-4-yl]methoxy}phenyl)isoquinoline-3-carboxylic acid, Farnesoid X receptor, Nuclear receptor coactivator 1, ... 著者 Madauss, K.P, Williams, S.P, Deaton, D.N. 登録日 2010-10-13 公開日 2011-08-31 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Conformationally constrained farnesoid X receptor (FXR) agonists: Heteroaryl replacements of the naphthalene. Bioorg.Med.Chem.Lett., 21, 2011
2RET	The crystal structure of a binary complex of two pseudopilins: EpsI and EpsJ from the Type 2 Secretion System of Vibrio vulnificus 分子名称: CHLORIDE ION, EpsJ, Pseudopilin EpsI, ... 著者 Yanez, M.E, Korotkov, K.V, Abendroth, J, Hol, W.G.J. 登録日 2007-09-27 公開日 2008-02-05 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 The crystal structure of a binary complex of two pseudopilins: EpsI and EpsJ from the type 2 secretion system of Vibrio vulnificus. J.Mol.Biol., 375, 2008
1O7O	Roles of Individual Residues of Alpha-1,3 Galactosyltransferases in Substrate Binding and Catalysis 分子名称: MANGANESE (II) ION, N-ACETYLLACTOSAMINIDE ALPHA-1,3-GALACTOSYLTRANSFERASE, URIDINE-5'-DIPHOSPHATE, ... 著者 Zhang, Y, Swaminathan, G.J, Deshpande, A, Natesh, R, Xie, Z, Acharya, K.R, Brew, K. 登録日 2002-11-11 公開日 2003-11-06 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Roles of individual enzyme-substrate interactions by alpha-1,3-galactosyltransferase in catalysis and specificity. Biochemistry, 42, 2003
1WU1	Factor Xa in complex with the inhibitor 4-[(5-chloroindol-2-yl)sulfonyl]-2-(2-methylpropyl)-1-[[5-(pyridin-4-yl) pyrimidin-2-yl]carbonyl]piperazine 分子名称: 5-CHLORO-2-({3-ISOBUTYL-4-[(5-PYRIDIN-4-YLPYRIMIDIN-2-YL)CARBONYL]PIPERAZIN-1-YL}SULFONYL)-1H-INDOLE, CALCIUM ION, Coagulation factor X, ... 著者 Suzuki, M. 登録日 2004-11-29 公開日 2005-11-29 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Design, synthesis, and biological activity of non-basic compounds as factor Xa inhibitors: SAR study of S1 and aryl binding sites Bioorg.Med.Chem., 13, 2005
4P6J	Crystal Structure of the Computationally Designed Transmembrane Metallotransporter with 4-bromophenylalanine in Octyl Glucoside 分子名称: Computationally Designed Transporter of Zn(II) and Proton, SULFATE ION 著者 Joh, N.H, Acharya, R, DeGrado, W.F. 登録日 2014-03-25 公開日 2014-12-24 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 De novo design of a transmembrane Zn2+-transporting four-helix bundle. Science, 346, 2014
4P6K	Crystal Structure of the Computationally Designed Transmembrane Metallotransporter with 4-bromophenylalanine in Lipidic Cubic Phase 分子名称: Computationally Designed Transporter of Zn(II) and Proton 著者 Joh, N.H, Acharya, R, DeGrado, W.F. 登録日 2014-03-25 公開日 2014-12-24 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.704 Å) 主引用文献 De novo design of a transmembrane Zn2+-transporting four-helix bundle. Science, 346, 2014
4P58	Crystal structure of mouse comt bound to an inhibitor 分子名称: 1',3'-dimethyl-1H,1'H-3,4'-bipyrazole, Catechol O-methyltransferase 著者 Lanier, M. 登録日 2014-03-15 公開日 2014-06-25 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.06 Å) 主引用文献 A fragment-based approach to identifying S-adenosyl-l-methionine -competitive inhibitors of catechol O-methyl transferase (COMT). J.Med.Chem., 57, 2014
1LU1	THE STRUCTURE OF THE DOLICHOS BIFLORUS SEED LECTIN IN COMPLEX WITH THE FORSSMAN DISACCHARIDE 分子名称: 2-acetamido-2-deoxy-alpha-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose, ADENINE, CALCIUM ION, ... 著者 Hamelryck, T.W, Loris, R, Bouckaert, J, Strecker, G, Imberty, A, Fernandez, E, Wyns, L, Etzler, M.E. 登録日 1998-07-24 公開日 1998-12-09 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Carbohydrate binding, quaternary structure and a novel hydrophobic binding site in two legume lectin oligomers from Dolichos biflorus. J.Mol.Biol., 286, 1999
4AA7	E.coli GlmU in complex with an antibacterial inhibitor 分子名称: BIFUNCTIONAL PROTEIN GLMU, N-(2,4-dimethoxy-5-{[(2R)-2-methyl-2,3-dihydro-1H-indol-1-yl]sulfonyl}phenyl)acetamide, SULFATE ION 著者 Otterbein, L, Breed, J, Ogg, D.J. 登録日 2011-11-30 公開日 2012-08-15 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Inhibitors of Acetyltransferase Domain of N-Acetylglucosamine-1-Phosphate-Uridyltransferase/ Glucosamine-1-Phosphate-Acetyltransferase (Glmu). Part 1: Hit to Lead Evaluation of a Novel Arylsulfonamide Series. Bioorg.Med.Chem.Lett., 22, 2012
4AAW	S.pneumoniae GlmU in complex with an antibacterial inhibitor 分子名称: 4-{[1-(2-{[({5-[(3-carboxypropanoyl)amino]-2,4-dimethoxyphenyl}sulfonyl)amino]methyl}phenyl)piperidin-4-yl]methoxy}-4-oxobutanoic acid, BIFUNCTIONAL PROTEIN GLMU, SULFATE ION 著者 Otterbein, L, Breed, J, Ogg, D.J. 登録日 2011-12-05 公開日 2012-02-15 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Inhibitors of Acetyltransferase Domain of N-Acetylglucosamine-1-Phosphate-Uridyltransferase/ Glucosamine-1-Phosphate-Acetyltransferase (Glmu). Part 1: Hit to Lead Evaluation of a Novel Arylsulfonamide Series. Bioorg.Med.Chem.Lett., 22, 2012
1GXU	Hydrogenase Maturation Protein HypF "acylphosphatase-like" N-terminal domain (HypF-ACP) in complex with a substrate. Crystal grown in the presence of carbamoylphosphate 分子名称: DIHYDROGENPHOSPHATE ION, HYDROGENASE MATURATION PROTEIN HYPF 著者 Rosano, C, Zuccotti, S, Stefani, M, Bucciantini, M, Ramponi, G, Bolognesi, M. 登録日 2002-04-11 公開日 2002-09-12 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.27 Å) 主引用文献 Crystal Structure and Anion Binding in the Prokaryotic Hydrogenase Maturation Factor Hypf Acylphosphatase-Like Domain J.Mol.Biol., 321, 2002

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