4ORK
Crystal Structure of the Phosphotransferase Domain of the Bifunctional Aminoglycoside Resistance Enzyme AAC(6')-Ie-APH(2'')-Ia
Summary for 4ORK
Entry DOI | 10.2210/pdb4ork/pdb |
Descriptor | Bifunctional AAC/APH, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... (4 entities in total) |
Functional Keywords | kinase, antibiotic resistance, aminoglycosides and gtp, transferase |
Biological source | Staphylococcus aureus |
Cellular location | Cytoplasm: P0A0C1 |
Total number of polymer chains | 4 |
Total formula weight | 145760.04 |
Authors | Smith, C.A.,Toth, M.,Bhattacharya, M.,Frase, H.,Vakulenko, S.B. (deposition date: 2014-02-11, release date: 2014-07-02, Last modification date: 2024-02-28) |
Primary citation | Smith, C.A.,Toth, M.,Bhattacharya, M.,Frase, H.,Vakulenko, S.B. Structure of the phosphotransferase domain of the bifunctional aminoglycoside-resistance enzyme AAC(6')-Ie-APH(2'')-Ia. Acta Crystallogr.,Sect.D, 70:1561-1571, 2014 Cited by PubMed: 24914967DOI: 10.1107/S1399004714005331 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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