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4ORK

Crystal Structure of the Phosphotransferase Domain of the Bifunctional Aminoglycoside Resistance Enzyme AAC(6')-Ie-APH(2'')-Ia

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
Bifunctional AAC/APHpolymer30535948.24UniProt (P0A0C1)
Pfam (PF01636)
Staphylococcus aureus6'-aminoglycoside N-acetyltransferase, AAC(6'), 2''-aminoglycoside phosphotransferase, APH(2'')
2E, H, K, N
(A, B, C, D)
GUANOSINE-5'-DIPHOSPHATEnon-polymer443.24Chemie (GDP)
3F, G, I, J, L...
(A, B, C, D)
MAGNESIUM IONnon-polymer24.38Chemie (MG)
4Q, R, S, T
(A, B, C, D)
waterwater18.0207Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight143792.8
Non-Polymers*Number of molecules12
Total formula weight1967.2
All*Total formula weight145760.0
*Water molecules are not included.

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PDB entries from 2025-12-10

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