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4ORK

Crystal Structure of the Phosphotransferase Domain of the Bifunctional Aminoglycoside Resistance Enzyme AAC(6')-Ie-APH(2'')-Ia

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
Bifunctional AAC/APHpolymer30535948.24UniProt (P0A0C1)Staphylococcus aureus6'-aminoglycoside N-acetyltransferase, AAC(6'), 2''-aminoglycoside phosphotransferase, APH(2'')
2E, H, K, N
(A, B, C, D)
GUANOSINE-5'-DIPHOSPHATEnon-polymer443.24Chemie (GDP)
PubChem (136073927)
PubChem (135398619)
PubChem (135402030)
PubChem (135431654)
PubChem (135566337)
PubChem (135760556)
PubChem (136026707)
PubChem (136053418)
PubChem (136663964)
PubChem (136664748)
PubChem (136759848)
PubChem (136759849)
PubChem (136759850)
PubChem (136836636)
PubChem (136847074)
PubChem (172898537)
3F, G, I, J, L...
(A, B, C, D)
MAGNESIUM IONnon-polymer24.38Chemie (MG)
PubChem (888)
4Q, R, S, T
(A, B, C, D)
waterwater18.0207Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight143792.8
Non-Polymers*Number of molecules12
Total formula weight1967.2
All*Total formula weight145760.0
*Water molecules are not included.

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PDB entries from 2026-05-13

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