2QMV

High Resolution Structure of Peroxisone Proliferation-Activated Receptor gamma and Characterisation of its Interaction with the Co-activator Transcriptional Intermediary Factor 2

Summary for 2QMV

DescriptorPeroxisome proliferator-activated receptor gamma (1 entity in total)
Functional Keywordsperoxisome profileration activated receptor gamma, pparg, transcriptional intermediary factor 2 (tif2), protein structure, activator, diabetes mellitus, disease mutation, dna-binding, metal-binding, nucleus, obesity, phosphorylation, transcription regulation, zinc-finger, transcription regulator
Biological sourceHomo sapiens (Human)
Cellular locationNucleus P37231
Total number of polymer chains1
Total molecular weight30833.85
Authors
Hartl, R.,Riepl, H.,Kauschke, S.,Kalbitzer, H.R.,Maurer, T. (deposition date: 2007-07-17, release date: 2008-09-02, Last modification date: 2012-02-22)
Primary citation
Moras, D.,Gronemeyer, H.,Gaal, V.L.,Scheen, A.J.,Cock, T.-A.,Houten, S.M.,Auwerx, J.,Stumvoll, M.,Haering, H.,Uppenberg, J.,Svensson, C.,Jaki, M.,Bertilsson, G.,Jendeberg, L.,Berkenstam, A.
High Resolution Structure of Peroxisone Proliferation-Activated Receptor gamma and Characterisation of its Interaction with the Co-activator Transcriptional Intermediary Factor 2
To be Published,
Experimental method
SOLUTION NMR
NMR Information
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Structure validation

ClashscoreRamachandran outliersSidechain outliers16114.3%41.2%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures
Download full validation report