4AA7
E.coli GlmU in complex with an antibacterial inhibitor
Summary for 4AA7
Entry DOI | 10.2210/pdb4aa7/pdb |
Related | 1FWY 1FXJ 1HV9 |
Descriptor | BIFUNCTIONAL PROTEIN GLMU, N-(2,4-dimethoxy-5-{[(2R)-2-methyl-2,3-dihydro-1H-indol-1-yl]sulfonyl}phenyl)acetamide, SULFATE ION, ... (4 entities in total) |
Functional Keywords | transferase, acetyl transferase, transferase-inhibitor complex |
Biological source | ESCHERICHIA COLI |
Total number of polymer chains | 2 |
Total formula weight | 50513.42 |
Authors | Otterbein, L.,Breed, J.,Ogg, D.J. (deposition date: 2011-11-30, release date: 2012-08-15, Last modification date: 2023-12-20) |
Primary citation | Green, O.M.,McKenzie, A.R.,Shapiro, A.B.,Otterbein, L.,Ni, H.,Patten, A.,Stokes, S.,Albert, R.,Kawatkar, S.,Breed, J. Inhibitors of Acetyltransferase Domain of N-Acetylglucosamine-1-Phosphate-Uridyltransferase/ Glucosamine-1-Phosphate-Acetyltransferase (Glmu). Part 1: Hit to Lead Evaluation of a Novel Arylsulfonamide Series. Bioorg.Med.Chem.Lett., 22:1510-, 2012 Cited by PubMed: 22297115DOI: 10.1016/J.BMCL.2012.01.016 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
Download full validation report