7NI6
 
 | | Human ATM kinase with bound ATPyS | | 分子名称: | MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Serine-protein kinase ATM, ... | | 著者 | Stakyte, K, Rotheneder, M, Lammens, K, Bartho, J.D. | | 登録日 | 2021-02-11 | | 公開日 | 2021-09-01 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Molecular basis of human ATM kinase inhibition.
Nat.Struct.Mol.Biol., 28, 2021
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3M9K
 | | Crystal structure of human thioredoxin C69/73S double-mutant, oxidized form | | 分子名称: | (4S,5S)-1,2-DITHIANE-4,5-DIOL, SULFATE ION, Thioredoxin | | 著者 | Weichsel, A, Montfort, W.R. | | 登録日 | 2010-03-22 | | 公開日 | 2010-08-11 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Crystal structure of human thioredoxin revealing an unraveled helix and exposed S-nitrosation site.
Protein Sci., 19, 2010
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7Z13
 | | S. cerevisiae CMGE dimer nucleating origin DNA melting | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 45, ... | | 著者 | Lewis, J.S, Sousa, J.S, Costa, A. | | 登録日 | 2022-02-24 | | 公開日 | 2022-06-15 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Mechanism of replication origin melting nucleated by CMG helicase assembly.
Nature, 606, 2022
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5WEI
 | | Crystal structure of the influenza virus PA endonuclease (E119D mutant) in complex with inhibitor 7a (SRI-29770) | | 分子名称: | 2-[(2S)-1-(2,6-dichlorobenzene-1-carbonyl)pyrrolidin-2-yl]-5-hydroxy-6-oxo-N-(2-phenylethyl)-1,6-dihydropyrimidine-4-carboxamide, MANGANESE (II) ION, Polymerase acidic protein, ... | | 著者 | Kumar, G, White, S.W. | | 登録日 | 2017-07-10 | | 公開日 | 2017-12-27 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Protein-Structure Assisted Optimization of 4,5-Dihydroxypyrimidine-6-Carboxamide Inhibitors of Influenza Virus Endonuclease.
Sci Rep, 7, 2017
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5IRC
 | | p190A GAP domain complex with RhoA | | 分子名称: | CHLORIDE ION, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Derewenda, U, Derewenda, Z. | | 登録日 | 2016-03-12 | | 公開日 | 2016-08-17 | | 最終更新日 | 2019-12-25 | | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | | 主引用文献 | Deciphering the Molecular and Functional Basis of RHOGAP Family Proteins: A SYSTEMATIC APPROACH TOWARD SELECTIVE INACTIVATION OF RHO FAMILY PROTEINS.
J.Biol.Chem., 291, 2016
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1SRS
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2E70
 | | Solution structure of the fifth KOW motif of human transcription elongation factor SPT5 | | 分子名称: | Transcription elongation factor SPT5 | | 著者 | Tanabe, W, Suzuki, S, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2007-01-05 | | 公開日 | 2007-07-10 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the fifth KOW motif of human transcription elongation factor SPT5
To be Published
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1LWM
 | | Solution Structure of the Sequence-Non-Specific HMGB protein NHP6A | | 分子名称: | NONHISTONE CHROMOSOMAL PROTEIN 6A | | 著者 | Masse, J.E, Wong, B, Yen, Y.-M, Allain, F.H.-T, Johnson, R.C, Feigon, J. | | 登録日 | 2002-05-31 | | 公開日 | 2002-10-16 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The S. cerevisiae architectural HMGB protein NHP6A complexed with DNA: DNA and protein conformational changes upon binding
J.Mol.Biol., 323, 2002
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3BAG
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3BAU
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3BAQ
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3BA5
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3BA4
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3BAH
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3B9U
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3BA7
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1Z92
 | | structure of interleukin-2 with its alpha receptor | | 分子名称: | Interleukin-2, Interleukin-2 receptor alpha chain | | 著者 | Rickert, M, Wang, X.Q, Goriatcheva, N, Boulanger, M.J, Garcia, K.C. | | 登録日 | 2005-03-31 | | 公開日 | 2005-06-07 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | The structure of interleukin-2 complexed with its alpha receptor.
Science, 308, 2005
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3BAV
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1V0O
 | | Structure of P. falciparum PfPK5-Indirubin-5-sulphonate ligand complex | | 分子名称: | 2',3-DIOXO-1,1',2',3-TETRAHYDRO-2,3'-BIINDOLE-5'-SULFONIC ACID, CELL DIVISION CONTROL PROTEIN 2 HOMOLOG | | 著者 | Holton, S, Merckx, A, Burgess, D, Doerig, C, Noble, M, Endicott, J. | | 登録日 | 2004-03-31 | | 公開日 | 2004-04-07 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structures of P. Falciparum Pfpk5 Test the Cdk Regulation Paradigm and Suggest Mechanisms of Small Molecule Inhibition
Structure, 11, 2003
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3BB2
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2FIX
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1M47
 | | Crystal Structure of Human Interleukin-2 | | 分子名称: | SULFATE ION, interleukin-2 | | 著者 | Arkin, M.A, Randal, M, DeLano, W.L, Hyde, J, Luong, T.N, Oslob, J.D, Raphael, D.R, Taylor, L, Wang, J, Wells, J.A, McDowell, R.S, Wells, J.A, Braisted, A.C. | | 登録日 | 2002-07-02 | | 公開日 | 2002-07-31 | | 最終更新日 | 2017-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | Binding of small molecules to an adaptive protein-protein interface.
Proc.Natl.Acad.Sci.USA, 100, 2003
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1M4C
 | | Crystal Structure of Human Interleukin-2 | | 分子名称: | interleukin-2 | | 著者 | Arkin, M.A, Randal, M, DeLano, W.L, Hyde, J, Luong, T.N, Oslob, J.D, Raphael, D.R, Taylor, L, Wang, J, McDowell, R.S, Wells, J.A, Braisted, A.C. | | 登録日 | 2002-07-02 | | 公開日 | 2002-07-31 | | 最終更新日 | 2017-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Binding of small molecules to an adaptive
protein-protein interface
Proc.Natl.Acad.Sci.USA, 100, 2003
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1M49
 | | Crystal Structure of Human Interleukin-2 Complexed with SP-1985 | | 分子名称: | 2-[2-(1-CARBAMIMIDOYL-PIPERIDIN-3-YL)-ACETYLAMINO]-3-{4-[2-(3-OXALYL-1H-INDOL-7-YL)ETHYL]-PHENYL}-PROPIONIC ACID METHYL ESTER, interleukin-2 | | 著者 | Arkin, M.A, Randal, M, DeLano, W.L, Hyde, J, Luong, T.N, Oslob, J.D, Raphael, D.R, Taylor, L, Wang, J, McDowell, R.S, Wells, J.A, Braisted, A.C. | | 登録日 | 2002-07-02 | | 公開日 | 2002-07-31 | | 最終更新日 | 2017-10-11 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Binding of small molecules to an adaptive
protein-protein interface
Proc.Natl.Acad.Sci.USA, 100, 2003
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2GNQ
 | | Structure of wdr5 | | 分子名称: | CHLORIDE ION, WD-repeat protein 5 | | 著者 | Min, J, Schuetz, A, Allali-Hassani, A, Loppnau, P, Vedadi, M, Weigelt, J, Sundstrom, M, Edwards, A.M, Arrowsmith, C.H, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC) | | 登録日 | 2006-04-10 | | 公開日 | 2006-06-06 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural basis for molecular recognition and presentation of histone H3 By WDR5.
Embo J., 25, 2006
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