7NI6

Human ATM kinase with bound ATPyS

Summary for 7NI6

• Entry DOI: 10.2210/pdb7ni6/pdb
• Related: 7NI4 7NI5
• EMDB information: 12343 12345 12346 12347 12350 12351 12352
• Descriptor: Serine-protein kinase ATM, ZINC ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... (4 entities in total)
• Functional Keywords: kinase, inhibitor, dna damage response, cancer research, signaling protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 710278.30

Authors

Stakyte, K.,Rotheneder, M.,Lammens, K.,Bartho, J.D. (deposition date: 2021-02-11, release date: 2021-09-01, Last modification date: 2021-10-20)

• Primary citation: Stakyte, K.,Rotheneder, M.,Lammens, K.,Bartho, J.D.,Gradler, U.,Fuchss, T.,Pehl, U.,Alt, A.,van de Logt, E.,Hopfner, K.P.; Molecular basis of human ATM kinase inhibition.; Nat.Struct.Mol.Biol., 28:789-798, 2021; PubMed: 34556870; DOI: 10.1038/s41594-021-00654-x

Experimental method

ELECTRON MICROSCOPY (2.8 Å)