7F7E
 
 | | SARS-CoV-2 S protein RBD in complex with A5-10 Fab | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of A5-10 Fab, Light chain of A5-10 Fab, ... | | 著者 | Dou, Y, Wang, X, Wang, K, Liu, P, Lu, B. | | 登録日 | 2021-06-29 | | 公開日 | 2022-02-02 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | | 主引用文献 | Etesevimab in combination with JS026 neutralizing SARS-CoV-2 and its variants.
Emerg Microbes Infect, 11, 2022
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1IGC
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5HMG
 | | REFINEMENT OF THE INFLUENZA VIRUS HEMAGGLUTININ BY SIMULATED ANNEALING | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain, ... | | 著者 | Weis, W.I, Bruenger, A.T, Skehel, J.J, Wiley, D.C. | | 登録日 | 1989-09-11 | | 公開日 | 1991-01-15 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Refinement of the influenza virus hemagglutinin by simulated annealing.
J.Mol.Biol., 212, 1990
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7N0X
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7N8Q
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2VXV
 | | Crystal structure of human IgG ABT-325 Fab Fragment | | 分子名称: | 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, GLYCEROL, HUMAN IGG ABT-325 | | 著者 | Argiriadi, M.A, Xiang, T, Wu, C, Ghayur, T, Borhani, D.W. | | 登録日 | 2008-07-10 | | 公開日 | 2009-06-23 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | | 主引用文献 | Unusual Water-Mediated Antigenic Recognition of the Proinflammatory Cytokine Interleukin-18.
J.Biol.Chem., 284, 2009
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3HMG
 | | REFINEMENT OF THE INFLUENZA VIRUS HEMAGGLUTININ BY SIMULATED ANNEALING | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, HEMAGGLUTININ, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | 著者 | Weis, W.I, Bruenger, A.T, Skehel, J.J, Wiley, D.C. | | 登録日 | 1989-09-11 | | 公開日 | 1991-01-15 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Refinement of the influenza virus hemagglutinin by simulated annealing.
J.Mol.Biol., 212, 1990
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6AQ7
 | | Structure of POM6 FAB fragment complexed with mouse PrPc | | 分子名称: | 3,3',3''-phosphanetriyltripropanoic acid, GLYCEROL, Major prion protein, ... | | 著者 | Baral, P.K, Swayampakula, M, James, M.N.G. | | 登録日 | 2017-08-18 | | 公開日 | 2018-04-04 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | | 主引用文献 | Structural characterization of POM6 Fab and mouse prion protein complex identifies key regions for prions conformational conversion.
FEBS J., 285, 2018
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3O2V
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8IL3
 | | Cryo-EM structure of CD38 in complex with FTL004 | | 分子名称: | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, Heavy chain, Light chain | | 著者 | Yang, J, Wang, Y, Zhang, G. | | 登録日 | 2023-03-01 | | 公開日 | 2023-03-29 | | 実験手法 | ELECTRON MICROSCOPY (3.86 Å) | | 主引用文献 | FTL004, an anti-CD38 mAb with negligible RBC binding and enhanced pro-apoptotic activity, is a novel candidate for treatments of multiple myeloma and non-Hodgkin lymphoma.
J Hematol Oncol, 15, 2022
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3O2W
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3GHE
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3GHB
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6DZW
 | | Cryo-EM structure of the ts2-inactive human serotonin transporter in complex with paroxetine and 15B8 Fab and 8B6 ScFv | | 分子名称: | 15B8 antibody heavy chain, 15B8 antibody light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Coleman, J.A, Yang, D, Gouaux, E. | | 登録日 | 2018-07-05 | | 公開日 | 2019-04-24 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | | 主引用文献 | Serotonin transporter-ibogaine complexes illuminate mechanisms of inhibition and transport.
Nature, 569, 2019
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5V4E
 | | Engineered human IgG Fc domain glyco801 (Fc801) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Yan, W, Marshall, N, Zhang, Y.J. | | 登録日 | 2017-03-09 | | 公開日 | 2017-06-21 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (3.216 Å) | | 主引用文献 | IgG Fc domains that bind C1q but not effector Fc gamma receptors delineate the importance of complement-mediated effector functions.
Nat. Immunol., 18, 2017
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2VDP
 | | Integrin AlphaIIbBeta3 Headpiece Bound to Fibrinogen Gamma chain peptide,LGGAKQAGDV | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, FIBRINOGEN, ... | | 著者 | Springer, T.A, Zhu, J, Xiao, T. | | 登録日 | 2007-10-10 | | 公開日 | 2008-09-02 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural Basis for Distinctive Recognition of Fibrinogen Gammac Peptide by the Platelet Integrin Alphaiibbeta3.
J.Cell Biol., 182, 2008
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2VDO
 | | Integrin AlphaIIbBeta3 Headpiece Bound to Fibrinogen Gamma chain peptide, HHLGGAKQAGDV | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, FIBRINOGEN, ... | | 著者 | Springer, T.A, Zhu, J, Xiao, T. | | 登録日 | 2007-10-10 | | 公開日 | 2008-09-02 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | | 主引用文献 | Structural Basis for Distinctive Recognition of Fibrinogen Gammac Peptide by the Platelet Integrin Alphaiibbeta3.
J.Cell Biol., 182, 2008
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2VDR
 | | Integrin AlphaIIbBeta3 Headpiece Bound to a chimeric Fibrinogen Gamma chain peptide, LGGAKQRGDV | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, FIBRINOGEN, ... | | 著者 | Springer, T.A, Zhu, J, Xiao, T. | | 登録日 | 2007-10-10 | | 公開日 | 2008-09-02 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural Basis for Distinctive Recognition of Fibrinogen Gammac Peptide by the Platelet Integrin Alphaiibbeta3.
J.Cell Biol., 182, 2008
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2VDQ
 | | Integrin AlphaIIbBeta3 Headpiece Bound to a Chimeric Fibrinogen Gamma chain peptide, HHLGGAKQRGDV | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, FIBRINOGEN, ... | | 著者 | Springer, T.A, Zhu, J, Xiao, T. | | 登録日 | 2007-10-10 | | 公開日 | 2008-09-02 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | | 主引用文献 | Structural Basis for Distinctive Recognition of Fibrinogen Gammac Peptide by the Platelet Integrin Alphaiibbeta3.
J.Cell Biol., 182, 2008
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7M53
 | | B6 Fab fragment bound to the SARS-CoV/SARS-CoV-2 spike stem helix peptide | | 分子名称: | B6 antigen-binding (Fab) fragment heavy chain, B6 antigen-binding (Fab) fragment light chain, GLYCEROL, ... | | 著者 | Sauer, M.M, Park, Y.J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | | 登録日 | 2021-03-22 | | 公開日 | 2021-05-26 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Structural basis for broad coronavirus neutralization.
Nat.Struct.Mol.Biol., 28, 2021
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7M51
 | | B6 Fab fragment bound to the OC43 spike stem helix peptide | | 分子名称: | B6 antigen-binding (Fab) fragment heavy chain, B6 antigen-binding (Fab) fragment light chain, GLYCEROL, ... | | 著者 | Sauer, M.M, Park, Y.J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | | 登録日 | 2021-03-22 | | 公開日 | 2021-05-26 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural basis for broad coronavirus neutralization.
Nat.Struct.Mol.Biol., 28, 2021
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7M55
 | | B6 Fab fragment bound to the MERS-CoV spike stem helix peptide | | 分子名称: | B6 antigen binding fragment (Fab) heavy chain, B6 antigen binding fragment (Fab) light chain, GLYCEROL, ... | | 著者 | Sauer, M.M, Park, Y.J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | | 登録日 | 2021-03-22 | | 公開日 | 2021-05-26 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Structural basis for broad coronavirus neutralization.
Nat.Struct.Mol.Biol., 28, 2021
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7M5E
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7M52
 | | B6 Fab fragment bound to the HKU4 spike stem helix peptide | | 分子名称: | B6 antigen-binding (Fab) fragment heavy chain, B6 antigen-binding (Fab) fragment light chain, GLYCEROL, ... | | 著者 | Sauer, M.M, Park, Y.J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | | 登録日 | 2021-03-22 | | 公開日 | 2021-05-26 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structural basis for broad coronavirus neutralization.
Nat.Struct.Mol.Biol., 28, 2021
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5MP5
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