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6QLC
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The ssDNA-binding RNA polymerase cofactor Drc from Pseudomonas phage LUZ7
分子名称: PHOSPHATE ION, ssDNA binding RNA Polymerase cofactor
著者De Zitter, E, Boon, M, De Smet, J, Lavigne, R, Van Meervelt, L.
登録日2019-01-31
公開日2019-10-30
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献'Drc', a structurally novel ssDNA-binding transcription regulator of N4-related bacterial viruses.
Nucleic Acids Res., 48, 2020
6DF7
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TAF1-BD2 in complex with Cpd27 (6-(but-3-en-1-yl)-4-(1-methyl-6-(morpholine-4-carbonyl)-1H-benzo[d]imidazol-4-yl)-1,6-dihydro-7H-pyrrolo[2,3-c]pyridin-7-one)
分子名称: 6-(but-3-en-1-yl)-4-[1-methyl-6-(morpholine-4-carbonyl)-1H-benzimidazol-4-yl]-1,6-dihydro-7H-pyrrolo[2,3-c]pyridin-7-one, Transcription initiation factor TFIID subunit
著者Murray, J.M.
登録日2018-05-14
公開日2018-11-14
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献GNE-371, a Potent and Selective Chemical Probe for the Second Bromodomains of Human Transcription-Initiation-Factor TFIID Subunit 1 and Transcription-Initiation-Factor TFIID Subunit 1-like.
J. Med. Chem., 61, 2018
6DFH
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BG505 MD64 N332-GT2 SOSIP trimer in complex with germline-reverted BG18 fragment antigen binding
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ...
著者Ozorowski, G, Steichen, J.M, Schief, W.R, Ward, A.B.
登録日2018-05-14
公開日2019-11-06
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.85 Å)
主引用文献A generalized HIV vaccine design strategy for priming of broadly neutralizing antibody responses.
Science, 366, 2019
3GW2
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BU of 3gw2 by Molmil
Crystal structure of possible transcriptional regulatory protein (fragment 1-100) from Mycobacterium bovis. Northeast Structural Genomics Consortium Target MbR242E.
分子名称: Possible transcriptional regulatory arsR-family protein
著者Kuzin, A.P, Su, M, Seetharaman, J, Mao, M, Xiao, R, Ciccosanti, C, Wang, D, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
登録日2009-03-31
公開日2009-04-21
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Northeast Structural Genomics Consortium Target MbR242E
To be published
6DGA
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BU of 6dga by Molmil
Cronobacter turicensis RpfR quorum-sensing receptor RpfF interaction domain
分子名称: RpfR
著者Waldron, E.J, Neiditch, M.B.
登録日2018-05-17
公開日2019-01-02
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.19 Å)
主引用文献Structural basis of DSF recognition by its receptor RpfR and its regulatory interaction with the DSF synthase RpfF.
PLoS Biol., 17, 2019
6DGB
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BU of 6dgb by Molmil
Crystal structure of the C-terminal catalytic domain of IS1535 TnpA, an IS607-like serine recombinase
分子名称: IS607 family transposase IS1535
著者Chen, W.Y, Hancock, S.P, Cascio, D, Johnson, R.C.
登録日2018-05-17
公開日2018-07-18
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.52 Å)
主引用文献Multiple serine transposase dimers assemble the transposon-end synaptic complex during IS607-family transposition.
Elife, 7, 2018
1M5B
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BU of 1m5b by Molmil
X-RAY STRUCTURE OF THE GLUR2 LIGAND BINDING CORE (S1S2J) IN COMPLEX WITH 2-Me-Tet-AMPA AT 1.85 A RESOLUTION.
分子名称: (S)-2-AMINO-3-[3-HYDROXY-5-(2-METHYL-2H-TETRAZOL-5-YL)ISOXAZOL-4-YL]PROPIONIC ACID, Glutamate receptor 2, ZINC ION
著者Hogner, A, Kastrup, J.S, Jin, R, Liljefors, T, Mayer, M.L, Egebjerg, J, Larsen, I.K, Gouaux, E.
登録日2002-07-09
公開日2002-09-18
最終更新日2017-08-16
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural Basis for AMPA Receptor Activation and Ligand Selectivity: Crystal Structures of Five Agonist Complexes with the GluR2 Ligand-binding Core
J.Mol.Biol., 322, 2002
3HA9
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BU of 3ha9 by Molmil
The 1.7A Crystal Structure of a Thioredoxin-like Protein from Aeropyrum pernix
分子名称: uncharacterized Thioredoxin-like protein
著者Stein, A.J, Cuff, M.E, Sather, A, Hendricks, R, Freeman, L, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2009-05-01
公開日2009-05-19
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The 1.7A Crystal Structure of a Thioredoxin-like Protein from Aeropyrum pernix
To be Published
6DGU
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PER-2 class A extended-spectrum beta-lactamase crystal structure at 2.69 Angstrom resolution
分子名称: Beta-lactamase
著者Power, P, Ruggiero, M, Gutkind, G, Bonomo, R, Klinke, S.
登録日2018-05-18
公開日2019-05-22
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.691 Å)
主引用文献Structural Insights into the Inhibition of the Extended-Spectrum beta-Lactamase PER-2 by Avibactam.
Antimicrob.Agents Chemother., 63, 2019
6Q5V
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BU of 6q5v by Molmil
1-Cys SiPrx, a Prx6-family 1-Cys peroxiredoxin of the thermoacidophilic archaeon Sulfolobus islandicus
分子名称: Peroxiredoxin
著者Stroobants, S, Maes, D, Peeters, E, van Molle, I.
登録日2018-12-09
公開日2019-05-29
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.747 Å)
主引用文献Structure of the Prx6-subfamily 1-Cys peroxiredoxin from Sulfolobus islandicus.
Acta Crystallogr.,Sect.F, 75, 2019
2FRQ
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BU of 2frq by Molmil
Human Cathepsin S with Inhibitor CRA-26871
分子名称: N-[4-(AMINOMETHYL)-1,1-DIOXIDOTETRAHYDRO-2H-THIOPYRAN-4-YL]-3-(1-METHYLCYCLOPENTYL)-N~2~-[(1E)-N-(PHENYLSULFONYL)ETHANIMIDOYL]-L-ALANINAMIDE, cathepsin S
著者Somoza, J.R.
登録日2006-01-19
公開日2006-07-25
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Human Cathepsin S with Inhibitor CRA-26871
To be Published
2FPI
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BU of 2fpi by Molmil
Crystal structure of pig GTP-specific succinyl-CoA synthetase from polyethylene glycol
分子名称: SULFATE ION, Succinyl-CoA ligase [GDP-forming] alpha-chain, mitochondrial, ...
著者Fraser, M.E.
登録日2006-01-16
公開日2006-02-21
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Interactions of GTP with the ATP-grasp Domain of GTP-specific Succinyl-CoA Synthetase
J.Biol.Chem., 281, 2006
6QDT
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BU of 6qdt by Molmil
Crystal structure of 14-3-3sigma in complex with a RapGef2 pT740 phosphopeptide
分子名称: 14-3-3 protein sigma, CALCIUM ION, CHLORIDE ION, ...
著者Andrei, S.A, Kaplan, A, Fournier, A.E, Ottman, C.
登録日2019-01-02
公開日2020-01-29
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.702 Å)
主引用文献Polypharmacological Perturbation of the 14-3-3 Adaptor Protein Interactome Stimulates Neurite Outgrowth.
Cell Chem Biol, 27, 2020
2FPZ
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BU of 2fpz by Molmil
Human tryptase with 2-amino benzimidazole
分子名称: 2H-BENZOIMIDAZOL-2-YLAMINE, Tryptase beta-2
著者Somoza, J.R.
登録日2006-01-17
公開日2006-03-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure-guided design of Peptide-based tryptase inhibitors.
Biochemistry, 45, 2006
6DCS
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BU of 6dcs by Molmil
Stage III sporulation protein AF (SpoIIIAF)
分子名称: SULFATE ION, Stage III sporulation protein AF
著者Strynadka, N.C.J, Zeytuni, N, Camp, A.H, Flanagan, K.A.
登録日2018-05-08
公開日2018-07-18
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural and biochemical characterization of SpoIIIAF, a component of a sporulation-essential channel in Bacillus subtilis.
J. Struct. Biol., 204, 2018
6DD1
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BU of 6dd1 by Molmil
Crystal structure of VIM-2 complexed with compound 14
分子名称: ACETATE ION, Beta-lactamase class B VIM-2, ZINC ION, ...
著者Pemberton, O.A, Chen, Y.
登録日2018-05-08
公開日2019-05-08
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Heteroaryl Phosphonates as Noncovalent Inhibitors of Both Serine- and Metallocarbapenemases.
J.Med.Chem., 62, 2019
2FS2
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BU of 2fs2 by Molmil
Structure of the E. coli PaaI protein from the phyenylacetic acid degradation operon
分子名称: Phenylacetic acid degradation protein paaI, SULFATE ION
著者Kniewel, R, Buglino, J.A, Solorzano, V, Wu, J, Lima, C.D, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2006-01-20
公開日2006-02-07
最終更新日2021-02-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure, Function, and Mechanism of the Phenylacetate Pathway Hot Dog-fold Thioesterase PaaI
J.Biol.Chem., 281, 2006
2FS8
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Human beta-tryptase II with inhibitor CRA-29382
分子名称: ALLYL {(1S)-1-[(5-{4-[(2,3-DIHYDRO-1H-INDEN-2-YLAMINO)CARBONYL]BENZYL}-1,2,4-OXADIAZOL-3-YL)CARBONYL]-3-PYRROLIDIN-3-YLPROPYL}CARBAMATE, Tryptase beta-2
著者Somoza, J.R.
登録日2006-01-21
公開日2006-03-21
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure-guided design of Peptide-based tryptase inhibitors.
Biochemistry, 45, 2006
6Q8M
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BU of 6q8m by Molmil
GH10 endo-xylanase
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-xylanase, ...
著者Davies, G.J, Rowland, R.J, Wu, L, Moroz, O, Blagova, E.
登録日2018-12-15
公開日2019-06-05
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.42 Å)
主引用文献Dynamic and Functional Profiling of Xylan-Degrading Enzymes inAspergillusSecretomes Using Activity-Based Probes.
Acs Cent.Sci., 5, 2019
4O69
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BU of 4o69 by Molmil
Human cyclic GMP-AMP synthase (cGAS) in complex with sulfate ion
分子名称: Cyclic GMP-AMP synthase, SULFATE ION, ZINC ION
著者Zhang, X, Chen, Z, Zhang, X.W, Chen, Z.J.
登録日2013-12-20
公開日2014-02-05
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.252 Å)
主引用文献The Cytosolic DNA Sensor cGAS Forms an Oligomeric Complex with DNA and Undergoes Switch-like Conformational Changes in the Activation Loop.
Cell Rep, 6, 2014
6DLL
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BU of 6dll by Molmil
2.2 Angstrom Resolution Crystal Structure of P-Hydroxybenzoate Hydroxylase from Pseudomonas putida in Complex with FAD.
分子名称: CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, FORMIC ACID, ...
著者Minasov, G, Shuvalova, L, Kiryukhina, O, Dubrovska, I, Grimshaw, S, Kwon, K, Anderson, W.F, Satchell, K.J.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2018-06-01
公開日2018-06-13
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural comparison of p-hydroxybenzoate hydroxylase (PobA) from Pseudomonas putida with PobA from other Pseudomonas spp. and other monooxygenases.
Acta Crystallogr.,Sect.F, 75, 2019
2FUG
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BU of 2fug by Molmil
Crystal structure of the hydrophilic domain of respiratory complex I from Thermus thermophilus
分子名称: FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, IRON/SULFUR CLUSTER, ...
著者Sazanov, L.A, Hinchliffe, P.
登録日2006-01-26
公開日2006-02-14
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structure of the hydrophilic domain of respiratory complex I from Thermus thermophilus.
Science, 311, 2006
6QDS
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BU of 6qds by Molmil
Crystal structure of 14-3-3sigma in complex with a PAK6 pT99 phosphopeptide stabilized by semi-synthetic fusicoccane FC-NCPC
分子名称: 14-3-3 protein sigma, CHLORIDE ION, FC-NCPC, ...
著者Andrei, S.A, Kaplan, A, Fournier, A.E, Ottman, C.
登録日2019-01-02
公開日2020-01-29
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献Polypharmacological Perturbation of the 14-3-3 Adaptor Protein Interactome Stimulates Neurite Outgrowth.
Cell Chem Biol, 27, 2020
6DQX
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Actinobacillus ureae class Id ribonucleotide reductase alpha subunit
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, GLYCEROL, ...
著者McBride, M.J, Palowitch, G.M, Boal, A.K.
登録日2018-06-11
公開日2019-04-17
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Structures of Class Id Ribonucleotide Reductase Catalytic Subunits Reveal a Minimal Architecture for Deoxynucleotide Biosynthesis.
Biochemistry, 58, 2019
4OED
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BU of 4oed by Molmil
Crystal structure of AR-LBD bound with co-regulator peptide
分子名称: 5-ALPHA-DIHYDROTESTOSTERONE, Androgen receptor, Protein BUD31 homolog, ...
著者Liu, J.S, Hsu, C.L, Wu, W.G.
登録日2014-01-13
公開日2014-08-20
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.79 Å)
主引用文献Identification of a new androgen receptor (AR) co-regulator BUD31 and related peptides to suppress wild-type and mutated AR-mediated prostate cancer growth via peptide screening and X-ray structure analysis.
Mol Oncol, 8, 2014

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