5LXA

CRYSTAL STRUCTURE OF HUMAN ADIPONECTIN RECEPTOR 2 IN COMPLEX WITH A C18 FREE FATTY ACID AT 3.0 ANGSTROM RESOLUTION

Summary for 5LXA

Entry DOI	10.2210/pdb5lxa/pdb
Descriptor	Adiponectin receptor protein 2, Anti-CD30 moab Ki-4 scFv, ZINC ION, ... (6 entities in total)
Functional Keywords	progestin and adipoq receptor family, integral membrane protein, 7tm, ceramidase, membrane protein
Biological source	Homo sapiens (Human) More
Total number of polymer chains	2
Total formula weight	65755.00
Authors	Vasiliauskaite-Brooks, I.,Leyrat, C.,Hoh, F.,Granier, S. (deposition date: 2016-09-20, release date: 2017-03-22, Last modification date: 2019-10-16)
Primary citation	Vasiliauskaite-Brooks, I.,Sounier, R.,Rochaix, P.,Bellot, G.,Fortier, M.,Hoh, F.,De Colibus, L.,Bechara, C.,Saied, E.M.,Arenz, C.,Leyrat, C.,Granier, S. Structural insights into adiponectin receptors suggest ceramidase activity. Nature, 6:120-123, 2017 Cited by PubMed: 28329765 DOI: 10.1038/nature21714 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3 Å)

Structure validation