5LXA
CRYSTAL STRUCTURE OF HUMAN ADIPONECTIN RECEPTOR 2 IN COMPLEX WITH A C18 FREE FATTY ACID AT 3.0 ANGSTROM RESOLUTION
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016020 | cellular_component | membrane |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 401 |
| Chain | Residue |
| A | HIS202 |
| A | HIS348 |
| A | HIS352 |
| A | HOH501 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | binding site for residue OLA A 402 |
| Chain | Residue |
| A | TYR328 |
| A | HIS348 |
| A | PHE351 |
| A | PHE354 |
| A | HOH501 |
| A | ASP219 |
| A | TYR220 |
| A | ILE223 |
| A | PHE282 |
| A | TYR321 |
| site_id | AC3 |
| Number of Residues | 11 |
| Details | binding site for residue OLB A 403 |
| Chain | Residue |
| A | PRO130 |
| A | PHE132 |
| A | ARG133 |
| A | PHE136 |
| A | SER196 |
| A | HIS207 |
| A | ILE298 |
| A | GLY301 |
| A | PHE302 |
| H | HIS169 |
| H | ASN170 |
Functional Information from PROSITE/UniProt
| site_id | PS00213 |
| Number of Residues | 12 |
| Details | LIPOCALIN Lipocalin signature. GGS..EFEGRWRVI |
| Chain | Residue | Details |
| A | GLY-4-ILE106 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 20 |
| Details | TRANSMEM: Helical; Name=1 => ECO:0000269|PubMed:25855295 |
| Chain | Residue | Details |
| A | ASN148-PHE168 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 52 |
| Details | TOPO_DOM: Extracellular => ECO:0000269|PubMed:25855295 |
| Chain | Residue | Details |
| A | ARG169-LYS181 | |
| A | LEU235-PRO245 | |
| A | HIS295-GLY309 | |
| A | GLN370-LEU386 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 20 |
| Details | TRANSMEM: Helical; Name=2 => ECO:0000269|PubMed:25855295 |
| Chain | Residue | Details |
| A | VAL182-HIS202 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 33 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000269|PubMed:25855295 |
| Chain | Residue | Details |
| A | THR203-ARG213 | |
| A | ASP267-GLN273 | |
| A | ARG331-HIS348 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 20 |
| Details | TRANSMEM: Helical; Name=3 => ECO:0000269|PubMed:25855295 |
| Chain | Residue | Details |
| A | LEU214-TRP234 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 20 |
| Details | TRANSMEM: Helical; Name=4 => ECO:0000269|PubMed:25855295 |
| Chain | Residue | Details |
| A | CYS246-TRP266 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 20 |
| Details | TRANSMEM: Helical; Name=5 => ECO:0000269|PubMed:25855295 |
| Chain | Residue | Details |
| A | TYR274-LEU294 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 20 |
| Details | TRANSMEM: Helical; Name=6 => ECO:0000269|PubMed:25855295 |
| Chain | Residue | Details |
| A | GLN310-ALA330 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 20 |
| Details | TRANSMEM: Helical; Name=7 => ECO:0000269|PubMed:25855295 |
| Chain | Residue | Details |
| A | GLN349-LEU369 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:25855295 |
| Chain | Residue | Details |
| A | HIS202 | |
| A | HIS348 | |
| A | HIS352 |
