4RZM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4rzm by Molmil](/molmil-images/mine/4rzm) | Crystal structure of the Lsd19-lasalocid A complex | 分子名称: | CHLORIDE ION, Epoxide hydrolase LasB, FORMIC ACID, ... | 著者 | Mathews, I.I, Hotta, K, Chen, X, Kim, C.-Y. | 登録日 | 2014-12-22 | 公開日 | 2015-01-21 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | 主引用文献 | Epoxide hydrolase-lasalocid a structure provides mechanistic insight into polyether natural product biosynthesis. J.Am.Chem.Soc., 137, 2015
|
|
4NPN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4npn by Molmil](/molmil-images/mine/4npn) | Crystal structure of human tetra-SUMO-2 | 分子名称: | Small ubiquitin-related modifier 2 | 著者 | Kung, C.C.-H, Naik, M.T, Chen, C.L, Ma, C, Huang, T.H. | 登録日 | 2013-11-22 | 公開日 | 2014-10-15 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.633 Å) | 主引用文献 | Structural analysis of poly-SUMO chain recognition by the RNF4-SIMs domain. Biochem.J., 462, 2014
|
|
5ZM6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5zm6 by Molmil](/molmil-images/mine/5zm6) | Crystal structure of ORP1-ORD in complex with PI(4,5)P2 | 分子名称: | ACETATE ION, Oxysterol-binding protein-related protein 1, [(2~{S})-1-octadecanoyloxy-3-[oxidanyl-[(1~{R},2~{R},3~{S},4~{S},5~{S},6~{S})-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propan-2-yl] icosa-5,8,11,14-tetraenoate | 著者 | Dong, J, Wang, J, Luo, Z, Wu, J.W. | 登録日 | 2018-04-01 | 公開日 | 2019-02-27 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Allosteric enhancement of ORP1-mediated cholesterol transport by PI(4,5)P2/PI(3,4)P2. Nat Commun, 10, 2019
|
|
4F48
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4f48 by Molmil](/molmil-images/mine/4f48) | The X-ray structural of FimXEAL-c-di-GMP-PilZ complexes from Xanthomonas campestris | 分子名称: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), Putative uncharacterized protein, Type IV fimbriae assembly protein | 著者 | Chin, K.-H, Liao, Y.-T, Chou, S.-H. | 登録日 | 2012-05-10 | 公開日 | 2012-11-14 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural polymorphism of c-di-GMP bound to an EAL domain and in complex with a type II PilZ-domain protein. Acta Crystallogr.,Sect.D, 68, 2012
|
|
6NT8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6nt8 by Molmil](/molmil-images/mine/6nt8) | Cryo-EM structure of full-length chicken STING in the cGAMP-bound tetrameric state | 分子名称: | Stimulator of interferon genes protein, cGAMP | 著者 | Shang, G, Zhang, C, Chen, Z.J, Bai, X, Zhang, X. | 登録日 | 2019-01-28 | 公開日 | 2019-03-06 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (6.5 Å) | 主引用文献 | Cryo-EM structures of STING reveal its mechanism of activation by cyclic GMP-AMP. Nature, 567, 2019
|
|
3PP7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3pp7 by Molmil](/molmil-images/mine/3pp7) | Crystal structure of Leishmania mexicana pyruvate kinase in complex with the drug suramin, an inhibitor of glycolysis. | 分子名称: | 8,8'-[CARBONYLBIS[IMINO-3,1-PHENYLENECARBONYLIMINO(4-METHYL-3,1-PHENYLENE)CARBONYLIMINO]]BIS-1,3,5-NAPHTHALENETRISULFON IC ACID, GLYCEROL, POTASSIUM ION, ... | 著者 | Morgan, H.P, Auld, D.S, McNae, I.W, Nowicki, M.W, Michels, P.A.M, Fothergill-Gilmore, L.A, Walkinshaw, M.D. | 登録日 | 2010-11-24 | 公開日 | 2010-12-15 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | The trypanocidal drug suramin and other trypan blue mimetics are inhibitors of pyruvate kinases and bind to the adenosine site. J.Biol.Chem., 286, 2011
|
|
6K0V
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6k0v by Molmil](/molmil-images/mine/6k0v) | Catalytic domain of GH87 alpha-1,3-glucanase D1069A in complex with tetrasaccharides | 分子名称: | Alpha-1,3-glucanase, CALCIUM ION, SULFATE ION, ... | 著者 | Itoh, T, Intuy, R, Suyotha, W, Hayashi, J, Yano, S, Makabe, K, Wakayama, M, Hibi, T. | 登録日 | 2019-05-07 | 公開日 | 2019-12-25 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.504 Å) | 主引用文献 | Structural insights into substrate recognition and catalysis by glycoside hydrolase family 87 alpha-1,3-glucanase from Paenibacillus glycanilyticus FH11. Febs J., 287, 2020
|
|
8E73
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8e73 by Molmil](/molmil-images/mine/8e73) | Vigna radiata supercomplex I+III2 (full bridge) | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, CARDIOLIPIN, ... | 著者 | Maldonado, M, Letts, J.A. | 登録日 | 2022-08-23 | 公開日 | 2023-01-11 | 最終更新日 | 2023-02-08 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Plant-specific features of respiratory supercomplex I + III 2 from Vigna radiata. Nat.Plants, 9, 2023
|
|
6L8F
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6l8f by Molmil](/molmil-images/mine/6l8f) | |
6JXK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6jxk by Molmil](/molmil-images/mine/6jxk) | Rb+-bound E2-MgF state of the gastric proton pump (Wild-type) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, MAGNESIUM ION, ... | 著者 | Abe, K, Irie, K, Yamamoto, K. | 登録日 | 2019-04-23 | 公開日 | 2019-08-14 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (4.3 Å) | 主引用文献 | A single K + -binding site in the crystal structure of the gastric proton pump. Elife, 8, 2019
|
|
5VPJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5vpj by Molmil](/molmil-images/mine/5vpj) | The crystal structure of a thioesteras from Actinomadura verrucosospora. | 分子名称: | CHLORIDE ION, TETRAETHYLENE GLYCOL, Thioesterase | 著者 | Tan, K, Joachimiak, G, Endres, M, Phillips Jr, G.N, Joachmiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | 登録日 | 2017-05-05 | 公開日 | 2017-07-19 | 最終更新日 | 2019-12-04 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | The crystal structure of a thioesteras from Actinomadura verrucosospora. To Be Published
|
|
8GEN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8gen by Molmil](/molmil-images/mine/8gen) | E. eligens beta-glucuronidase bound to UNC10201652-glucuronide | 分子名称: | 8-(4-beta-D-glucopyranuronosylpiperazin-1-yl)-5-(morpholin-4-yl)-1,2,3,4-tetrahydro[1,2,3]triazino[4',5':4,5]thieno[2,3 -c]isoquinoline, Beta-glucuronidase | 著者 | Simpson, J.B, Redinbo, M.R. | 登録日 | 2023-03-07 | 公開日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.94 Å) | 主引用文献 | Diverse Human Therapeutics Impact Hormone and Neurotransmitter Homeostasis by Inhibiting Gut Microbial Enzymes To Be Published
|
|
8EC4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ec4 by Molmil](/molmil-images/mine/8ec4) | |
8EBI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ebi by Molmil](/molmil-images/mine/8ebi) | |
8GOG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8gog by Molmil](/molmil-images/mine/8gog) | Structure of streptavidin mutant (S112Y-K121E) complexed with biotin-cyclopentadienyl-rhodium (III)(Cp*-Rh(III)) | 分子名称: | CHLORIDE ION, GLYCEROL, RHODIUM(III) ION, ... | 著者 | Sairaman, A, Mukherjee, P, Maiti, D, Bhaumik, P. | 登録日 | 2022-08-24 | 公開日 | 2024-02-28 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Enantiodivergent synthesis of isoindolones catalysed by a Rh(III)-based artificial metalloenzyme Nat Synth, 2024
|
|
8ECF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ecf by Molmil](/molmil-images/mine/8ecf) | |
8EBR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ebr by Molmil](/molmil-images/mine/8ebr) | |
8GDZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8gdz by Molmil](/molmil-images/mine/8gdz) | CryoEM structure of beta-2-adrenergic receptor in complex with nucleotide-free Gs heterotrimer (#1 of 20) | 分子名称: | (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Papasergi-Scott, M.M, Skiniotis, G. | 登録日 | 2023-03-06 | 公開日 | 2024-03-06 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Time-resolved cryo-EM of G-protein activation by a GPCR. Nature, 629, 2024
|
|
8GE1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ge1 by Molmil](/molmil-images/mine/8ge1) | CryoEM structure of beta-2-adrenergic receptor in complex with nucleotide-free Gs heterotrimer (#2 of 20) | 分子名称: | (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Papasergi-Scott, M.M, Skiniotis, G. | 登録日 | 2023-03-06 | 公開日 | 2024-03-06 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Time-resolved cryo-EM of G-protein activation by a GPCR. Nature, 629, 2024
|
|
8GE2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ge2 by Molmil](/molmil-images/mine/8ge2) | CryoEM structure of beta-2-adrenergic receptor in complex with nucleotide-free Gs heterotrimer (#3 of 20) | 分子名称: | (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Papasergi-Scott, M.M, Skiniotis, G. | 登録日 | 2023-03-06 | 公開日 | 2024-03-06 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Time-resolved cryo-EM of G-protein activation by a GPCR. Nature, 629, 2024
|
|
8GE3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ge3 by Molmil](/molmil-images/mine/8ge3) | CryoEM structure of beta-2-adrenergic receptor in complex with nucleotide-free Gs heterotrimer (#4 of 20) | 分子名称: | (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Papasergi-Scott, M.M, Skiniotis, G. | 登録日 | 2023-03-06 | 公開日 | 2024-03-06 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Time-resolved cryo-EM of G-protein activation by a GPCR. Nature, 629, 2024
|
|
8GE4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ge4 by Molmil](/molmil-images/mine/8ge4) | CryoEM structure of beta-2-adrenergic receptor in complex with nucleotide-free Gs heterotrimer (#5 of 20) | 分子名称: | (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Papasergi-Scott, M.M, Skiniotis, G. | 登録日 | 2023-03-06 | 公開日 | 2024-03-06 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Time-resolved cryo-EM of G-protein activation by a GPCR. Nature, 629, 2024
|
|
8GE5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ge5 by Molmil](/molmil-images/mine/8ge5) | CryoEM structure of beta-2-adrenergic receptor in complex with nucleotide-free Gs heterotrimer (#6 of 20) | 分子名称: | (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Papasergi-Scott, M.M, Skiniotis, G. | 登録日 | 2023-03-06 | 公開日 | 2024-03-06 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Time-resolved cryo-EM of G-protein activation by a GPCR. Nature, 629, 2024
|
|
8GE6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ge6 by Molmil](/molmil-images/mine/8ge6) | CryoEM structure of beta-2-adrenergic receptor in complex with nucleotide-free Gs heterotrimer (#7 of 20) | 分子名称: | (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Papasergi-Scott, M.M, Skiniotis, G. | 登録日 | 2023-03-06 | 公開日 | 2024-03-06 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Time-resolved cryo-EM of G-protein activation by a GPCR. Nature, 629, 2024
|
|
8GE8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ge8 by Molmil](/molmil-images/mine/8ge8) | CryoEM structure of beta-2-adrenergic receptor in complex with nucleotide-free Gs heterotrimer (#9 of 20) | 分子名称: | (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Papasergi-Scott, M.M, Skiniotis, G. | 登録日 | 2023-03-06 | 公開日 | 2024-03-06 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Time-resolved cryo-EM of G-protein activation by a GPCR. Nature, 629, 2024
|
|