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5JDS
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BU of 5jds by Molmil
Crystal structure of PD-L1 complexed with a nanobody at 1.7 Angstron resolution
分子名称: CHLORIDE ION, Nanobody, Programmed cell death 1 ligand 1, ...
著者Zhou, A, Wei, H.
登録日2016-04-17
公開日2017-04-12
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural basis of a novel PD-L1 nanobody for immune checkpoint blockade.
Cell Discov, 3, 2017
5J8O
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BU of 5j8o by Molmil
Structure of human Programmed cell death 1 ligand 1 (PD-L1) with low molecular mass inhibitor
分子名称: (2R)-1-({3-bromo-4-[(2-methyl[1,1'-biphenyl]-3-yl)methoxy]phenyl}methyl)piperidine-2-carboxylic acid, Programmed cell death 1 ligand 1
著者Zak, K.M, Grudnik, P, Guzik, K, Zieba, B.J, Musielak, B, Doemling, P, Dubin, G, Holak, T.A.
登録日2016-04-08
公開日2016-04-27
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis for small molecule targeting of the programmed death ligand 1 (PD-L1).
Oncotarget, 7, 2016
5J89
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BU of 5j89 by Molmil
Structure of human Programmed cell death 1 ligand 1 (PD-L1) with low molecular mass inhibitor
分子名称: 1,2-ETHANEDIOL, N-{2-[({2-methoxy-6-[(2-methyl[1,1'-biphenyl]-3-yl)methoxy]pyridin-3-yl}methyl)amino]ethyl}acetamide, Programmed cell death 1 ligand 1
著者Zak, K.M, Grudnik, P, Guzik, K, Zieba, B.J, Musielak, B, Doemling, P, Dubin, G, Holak, T.A.
登録日2016-04-07
公開日2016-04-27
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural basis for small molecule targeting of the programmed death ligand 1 (PD-L1).
Oncotarget, 7, 2016
5J0B
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BU of 5j0b by Molmil
Structure of the immune receptor CD33 in complex with 6'-sialyllactose
分子名称: 2-(2-METHOXYETHOXY)ETHANOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Myeloid cell surface antigen CD33, ...
著者Dodd, R.B.
登録日2016-03-28
公開日2017-04-05
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献STRUCTURE OF LIGAND BOUND CD33 RECEPTOR ASSOCIATED WITH ALZHEIMER'S DISEASE
To Be Published
5J06
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BU of 5j06 by Molmil
Structure of the immune receptor CD33 in complex with 3'-sialyllactose
分子名称: 2-(2-METHOXYETHOXY)ETHANOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Myeloid cell surface antigen CD33, ...
著者Dodd, R.B.
登録日2016-03-27
公開日2017-04-05
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.66 Å)
主引用文献STRUCTURE OF LIGAND BOUND CD33 RECEPTOR ASSOCIATED WITH ALZHEIMER'S DISEASE
To Be Published
5IUS
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BU of 5ius by Molmil
Crystal structure of human PD-L1 in complex with high affinity PD-1 mutant
分子名称: CHLORIDE ION, Programmed cell death 1 ligand 1, Programmed cell death protein 1
著者Pascolutti, R, Sun, X, Kao, J, Maute, R, Ring, A.M, Bowman, G.R, Kruse, A.C.
登録日2016-03-18
公開日2016-09-28
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.889 Å)
主引用文献Structure and Dynamics of PD-L1 and an Ultra-High-Affinity PD-1 Receptor Mutant.
Structure, 24, 2016
5IR3
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BU of 5ir3 by Molmil
Crystal structure of the recombinant highest fibrillogenic natural mutant (obtained from patient AR) derived from lambda 6 light chain variable domain
分子名称: ACETATE ION, Ig lambda chain V-VI region AR
著者Hernandez-Santoyo, A, Rodriguez-Romero, A.
登録日2016-03-11
公開日2017-06-14
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Stabilizing an amyloidogenic lambda 6 light chain variable domain.
FEBS J., 284, 2017
5IMM
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BU of 5imm by Molmil
Nanobody targeting mouse Vsig4 in Spacegroup P212121
分子名称: Nanobody, Protein Vsig4
著者Wen, Y, Zheng, F.
登録日2016-03-06
公開日2017-01-11
最終更新日2017-07-05
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Structural evaluation of a nanobody targeting complement receptor Vsig4 and its cross reactivity
Immunobiology, 222, 2017
5IML
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BU of 5iml by Molmil
Nanobody targeting human Vsig4 in Spacegroup P212121
分子名称: Nanobody, V-set and immunoglobulin domain-containing protein 4
著者Wen, Y.
登録日2016-03-06
公開日2017-01-11
最終更新日2017-07-05
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural evaluation of a nanobody targeting complement receptor Vsig4 and its cross reactivity
Immunobiology, 222, 2017
5IMK
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BU of 5imk by Molmil
Nanobody targeting human Vsig4 in Spacegroup C2
分子名称: Nanobody, V-set and immunoglobulin domain-containing protein 4
著者Wen, Y.
登録日2016-03-06
公開日2017-01-11
最終更新日2017-07-05
実験手法X-RAY DIFFRACTION (1.227 Å)
主引用文献Structural evaluation of a nanobody targeting complement receptor Vsig4 and its cross reactivity
Immunobiology, 222, 2017
5IMO
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BU of 5imo by Molmil
Nanobody targeting mouse Vsig4 in Spacegroup P3221
分子名称: Nanobody, Protein Vsig4
著者Wen, Y, Zheng, F.
登録日2016-03-06
公開日2017-01-11
最終更新日2017-07-05
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural evaluation of a nanobody targeting complement receptor Vsig4 and its cross reactivity
Immunobiology, 222, 2017
5IKC
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BU of 5ikc by Molmil
X-RAY STRUCTURE OF THE N-TERMINAL DOMAIN OF HUMAN DOUBLECORTIN in complex with FAB
分子名称: CHLORIDE ION, Ighg protein, MAb 6H10 light chain, ...
著者Ruf, A, Stihle, M, Benz, J, Thoma, R, Rudolph, M.G.
登録日2016-03-03
公開日2016-05-18
最終更新日2020-03-11
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献Crystal Structures of the Human Doublecortin C- and N-terminal Domains in Complex with Specific Antibodies.
J.Biol.Chem., 291, 2016
5IJV
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BU of 5ijv by Molmil
Crystal structure of bovine Fab E03
分子名称: bovine Fab E03 heavy chain, bovine Fab E03 light chain
著者Stanfield, R.L, Wilson, I.A.
登録日2016-03-02
公開日2016-10-05
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Conservation and diversity in the ultralong third heavy-chain complementarity-determining region of bovine antibodies.
Sci Immunol, 1, 2016
5IHB
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BU of 5ihb by Molmil
Structure of the immune receptor CD33
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Myeloid cell surface antigen CD33
著者Dodd, R.B.
登録日2016-02-29
公開日2017-03-29
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Structure of ligand bound CD33 receptor associated with Alzheimer's disease
To Be Published
5IHU
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BU of 5ihu by Molmil
Crystal structure of bovine Fab B11
分子名称: bovine Fab B11 heavy chain, bovine Fab B11 light chain
著者Stanfield, R, Wilson, I.
登録日2016-02-29
公開日2016-10-05
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献Conservation and diversity in the ultralong third heavy-chain complementarity-determining region of bovine antibodies.
Sci Immunol, 1, 2016
5HYJ
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BU of 5hyj by Molmil
1E6 TCR in Complex with HLA-A02 carrying AQWGPDPAAA
分子名称: ALA-GLN-TRP-GLY-PRO-ASP-PRO-ALA-ALA-ALA, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
著者Rizkallah, P.J, Bulek, A.M, Cole, D.K, Sewell, A.K.
登録日2016-02-01
公開日2016-05-04
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.06 Å)
主引用文献A "hotspot" for autoimmune T cells in type 1 diabetes.
J.Clin.Invest., 126, 2016
5HHM
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BU of 5hhm by Molmil
Crystal Structure of the JM22 TCR in complex with HLA-A*0201 in complex with M1-F5L
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ...
著者Gras, S, Josephs, T.M, Rossjohn, J.
登録日2016-01-11
公開日2016-03-23
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Molecular basis for universal HLA-A*0201-restricted CD8+ T-cell immunity against influenza viruses.
Proc.Natl.Acad.Sci.USA, 113, 2016
5HHO
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BU of 5hho by Molmil
Crystal Structure of the JM22 TCR in complex with HLA-A*0201 in complex with M1-G4E
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ...
著者Gras, S, Josephs, T.M, Rossjohn, J.
登録日2016-01-11
公開日2016-03-23
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Molecular basis for universal HLA-A*0201-restricted CD8+ T-cell immunity against influenza viruses.
Proc.Natl.Acad.Sci.USA, 113, 2016
5HDO
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BU of 5hdo by Molmil
Crystal structure of a nanobody raised against urokinase-type plasminogen activator
分子名称: Anti-HCV NS3/4A serine protease immoglobulin heavy chain, CHLORIDE ION, SULFATE ION
著者Kromann-Hansen, T.
登録日2016-01-05
公開日2016-06-01
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献A Camelid-derived Antibody Fragment Targeting the Active Site of a Serine Protease Balances between Inhibitor and Substrate Behavior.
J.Biol.Chem., 291, 2016
5B21
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BU of 5b21 by Molmil
Dimer structure of murine Nectin-1 D1
分子名称: murine Nectin-1 D1
著者Sangawa, T, Takebe, K, Suzuki, M.
登録日2015-12-28
公開日2016-12-28
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Dimer structure of murine Nectin-1 D1
To Be Published
5B22
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BU of 5b22 by Molmil
Dimer structure of murine Nectin-3 D1D2
分子名称: Nectin-3, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Takebe, K, Sangawa, T, Katsutani, T, Narita, H, Suzuki, M.
登録日2015-12-28
公開日2016-12-28
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献Dimer structure of murine Nectin-3 D1D2
To Be Published
5FFL
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BU of 5ffl by Molmil
Crystal structure of mouse CD300lf at 1.6 Angstroms resolution.
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CD300 antigen-like family member F, ...
著者Nelson, C.A, Fremont, D.H.
登録日2015-12-18
公開日2016-08-31
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.602 Å)
主引用文献Discovery of a proteinaceous cellular receptor for a norovirus.
Science, 353, 2016
5FDY
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BU of 5fdy by Molmil
Crystal structure of the Voltage-gated Sodium Channel Beta 2 subunit extracellular domain, C72A/C75A mutant
分子名称: GLYCEROL, Sodium channel subunit beta-2
著者Das, S, Van Petegem, F.
登録日2015-12-16
公開日2016-03-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Binary architecture of the Nav1.2-beta 2 signaling complex.
Elife, 5, 2016
5FEB
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BU of 5feb by Molmil
Crystal structure of the Voltage-gated Sodium Channel Beta 2 subunit extracellular domain
分子名称: GLYCEROL, Sodium channel subunit beta-2
著者Das, S, Van Petegem, F.
登録日2015-12-16
公開日2016-03-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Binary architecture of the Nav1.2-beta 2 signaling complex.
Elife, 5, 2016
5F7F
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BU of 5f7f by Molmil
Human T-cell immunoglobulin and mucin domain protein 4 (hTIM-4)
分子名称: T-cell immunoglobulin and mucin domain-containing protein 4
著者Gao, G.F, Lu, G, Wang, H, Qi, J.
登録日2015-12-08
公開日2016-02-03
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.502 Å)
主引用文献Crystal structures of human TIM members: Ebolavirus entry-enhancing receptors
Chin.Sci.Bull., 60, 2015

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件を2024-07-17に公開中

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