PDB: 245396 件ウェブページステータス検索Chemie searchBIRD

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2XJ7	BtGH84 in complex with 6-acetamido-6-deoxy-castanospermine 分子名称: 6-ACETAMIDO-6-DEOXY-CASTANOSPERMINE, CALCIUM ION, O-GLCNACASE BT_4395 著者 He, Y, Davies, G.J. 登録日 2010-07-02 公開日 2010-09-29 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Inhibition of O-Glcnacase Using a Potent and Cell-Permeable Inhibitor Does not Induce Insulin Resistance in 3T3-L1 Adipocytes. Chem.Biol., 17, 2010
2WAP	3D-crystal structure of humanized-rat fatty acid amide hydrolase (FAAH) conjugated with the drug-like urea inhibitor PF-3845 分子名称: 4-(3-{[5-(trifluoromethyl)pyridin-2-yl]oxy}benzyl)piperidine-1-carboxylic acid, CHLORIDE ION, FATTY-ACID AMIDE HYDROLASE 1, ... 著者 Mileni, M, Kamtekar, S, Stevens, R.C. 登録日 2009-02-11 公開日 2009-05-05 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Discovery and Characterization of a Highly Selective Faah Inhibitor that Reduces Inflammatory Pain. Chem.Biol., 16, 2009
1VL0	CRYSTAL STRUCTURE OF A DTDP-4-DEHYDRORHAMNOSE REDUCTASE, RFBD ORTHOLOG (CA_C2315) FROM CLOSTRIDIUM ACETOBUTYLICUM ATCC 824 AT 2.05 A RESOLUTION 分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, DTDP-4-dehydrorhamnose reductase, rfbD ortholog, ... 著者 Joint Center for Structural Genomics (JCSG) 登録日 2004-06-30 公開日 2004-08-17 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Crystal structure of DTDP-4-dehydrorhamnose reductase, rfbD ortholog (CAC2315) from Clostridium acetobutylicum at 2.05 A resolution To be published
3PRY	Crystal structure of the middle domain of human HSP90-beta refined at 2.3 A resolution 分子名称: 1,2-ETHANEDIOL, GLYCEROL, Heat shock protein HSP 90-beta, ... 著者 Chaikuad, A, Pilka, E, Sharpe, T.D, Cooper, C.D.O, Phillips, C, Berridge, G, Ayinampudi, V, Fedorov, O, Keates, T, Thangaratnarajah, C, Zimmermann, T, Vollmar, M, Yue, W.W, Che, K.H, Krojer, T, Muniz, J.R.C, von Delft, F, Bountra, C, Arrowsmith, C.H, Weigelt, J, Edwards, A, Bullock, A, Structural Genomics Consortium (SGC) 登録日 2010-11-30 公開日 2010-12-15 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.28 Å) 主引用文献 Crystal structure of the middle domain of human HSP90-beta refined at 2.3 A resolution To be Published
219L	PROTEIN STRUCTURE PLASTICITY EXEMPLIFIED BY INSERTION AND DELETION MUTANTS IN T4 LYSOZYME 分子名称: 2-HYDROXYETHYL DISULFIDE, T4 LYSOZYME 著者 Vetter, I.R, Baase, W.A, Heinz, D.W, Xiong, J.-P, Snow, S, Matthews, B.W. 登録日 1996-09-23 公開日 1996-12-23 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.66 Å) 主引用文献 Protein structural plasticity exemplified by insertion and deletion mutants in T4 lysozyme. Protein Sci., 5, 1996
6HA1	Cryo-EM structure of a 70S Bacillus subtilis ribosome translating the ErmD leader peptide in complex with telithromycin 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Crowe-McAuliffe, C, Graf, M, Huter, P, Abdelshahid, M, Novacek, J, Wilson, D.N. 登録日 2018-08-07 公開日 2018-08-29 最終更新日 2024-11-20 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural basis for antibiotic resistance mediated by theBacillus subtilisABCF ATPase VmlR. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
3IPU	X-ray structure of benzisoxazole urea synthetic agonist bound to the LXR-alpha 分子名称: 4-{[methyl(3-{[7-propyl-3-(trifluoromethyl)-1,2-benzisoxazol-6-yl]oxy}propyl)carbamoyl]amino}benzoic acid, Nuclear receptor coactivator 1, Oxysterols receptor LXR-alpha, ... 著者 Fradera, X, Vu, D, Nimz, O, Skene, R, Hosfield, D, Wijnands, R, Cooke, A.J, Haunso, A, King, A, Bennet, D.J, McGuire, R, Uitdehaag, J.C.M. 登録日 2009-08-18 公開日 2010-06-02 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 X-ray structures of the LXRalpha LBD in its homodimeric form and implications for heterodimer signaling. J.Mol.Biol., 399, 2010
3KV4	Structure of PHF8 in complex with histone H3 分子名称: 1,2-ETHANEDIOL, FE (II) ION, Histone H3-like, ... 著者 Horton, J.R, Upadhyay, A.K, Qi, H.H, Zhang, X, Shi, Y, Cheng, X. 登録日 2009-11-29 公開日 2009-12-22 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.19 Å) 主引用文献 Enzymatic and structural insights for substrate specificity of a family of jumonji histone lysine demethylases. Nat.Struct.Mol.Biol., 17, 2010
3IO9	BimL12Y in complex with Mcl-1 分子名称: Bcl-2-like protein 11, Induced myeloid leukemia cell differentiation protein Mcl-1, ZINC ION 著者 Czabotar, P.E, Lee, E.F, Yang, H, Sleebs, B.E, Lessene, G, Colman, P.M, Smith, B.J, Fairlie, W.D. 登録日 2009-08-14 公開日 2009-09-01 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Conformational changes in Bcl-2 pro-survival proteins determine their capacity to bind ligands. J.Biol.Chem., 284, 2009
7FCP	Crystallographic structure of two neutralizing antibodies in complex with SARS-CoV-2 spike receptor-binding Domain (RBD) 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... 著者 Zheng, P, Jin, T. 登録日 2021-07-15 公開日 2022-06-15 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Ultrapotent neutralizing antibodies against SARS-CoV-2 with a high degree of mutation resistance. J.Clin.Invest., 132, 2022
3KR5	Structure of a protease 4 分子名称: (2S)-3-[(R)-[(1S)-1-amino-3-phenylpropyl](hydroxy)phosphoryl]-2-benzylpropanoic acid, CARBONATE ION, M17 leucyl aminopeptidase, ... 著者 McGowan, S, Whisstock, J.C. 登録日 2009-11-17 公開日 2010-02-02 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.56 Å) 主引用文献 Structure of the Plasmodium falciparum M17 aminopeptidase and significance for the design of drugs targeting the neutral exopeptidases Proc.Natl.Acad.Sci.USA, 107, 2010
7XXF	Structure of photosynthetic LH1-RC super-complex of Rhodopila globiformis 分子名称: (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, (6~{E},8~{E},10~{E},12~{E},14~{E},16~{E},18~{E},20~{E},22~{E},24~{E},26~{E},28~{E})-2,31-dimethoxy-2,6,10,14,19,23,27,31-octamethyl-dotriaconta-6,8,10,12,14,16,18,20,22,24,26,28-dodecaen-5-one, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, ... 著者 Tani, K, Kanno, R, Kurosawa, K, Takaichi, S, Nagashima, K.V.P, Hall, M, Yu, L.-J, Kimura, Y, Madigan, M.T, Mizoguchi, A, Humbel, B.M, Wang-Otomo, Z.-Y. 登録日 2022-05-30 公開日 2022-11-16 最終更新日 2022-11-23 実験手法 ELECTRON MICROSCOPY (2.24 Å) 主引用文献 An LH1-RC photocomplex from an extremophilic phototroph provides insight into origins of two photosynthesis proteins. Commun Biol, 5, 2022
3PYA	Crystal structure of ent-copalyl diphosphate synthase from Arabidopsis thaliana in complex with (S)-15-aza-14,15-dihydrogeranylgeranyl thiolodiphosphate 分子名称: Ent-copalyl diphosphate synthase, chloroplastic, GLYCEROL, ... 著者 Koksal, M, Christianson, D.W. 登録日 2010-12-12 公開日 2011-05-25 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Structure of ent-Copalyl Diphosphate Synthase from Arabidopsis thaliana, a Protonation-Dependent Diterpene Cyclase To be Published
4FH2	Structure of s70c beta-lactamase bound to sulbactam 分子名称: Beta-lactamase SHV-1, CYCLOHEXYL-HEXYL-BETA-D-MALTOSIDE, SULBACTAM 著者 Rodkey, E.A, van den Akker, F. 登録日 2012-06-05 公開日 2012-09-26 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.44 Å) 主引用文献 Crystal structure of a pre-acylation complex of the beta-lactamase inhibitor, sulbactam, bound to a sulfenamide bond containing thiol-beta-lactamase J.Am.Chem.Soc., 134, 2012
4FMV	Crystal Structure Analysis of a GH30 Endoxylanase from Clostridium papyrosolvens C71 分子名称: Glucuronoarabinoxylan endo-1,4-beta-xylanase 著者 Bales, E.B, Smith, J.K, St John, F.J, Hurlbert, J.C. 登録日 2012-06-18 公開日 2013-06-19 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 A novel member of glycoside hydrolase family 30 subfamily 8 with altered substrate specificity. Acta Crystallogr.,Sect.D, 70, 2014
2A70	Crystal structure of Emp47p carbohydrate recognition domain (CRD), monoclinic crystal form 2 分子名称: 1,2-ETHANEDIOL, Emp47p 著者 Satoh, T, Sato, K, Kanoh, A, Yamashita, K, Katoh, R, Nakano, A, Wakatsuki, S. 登録日 2005-07-04 公開日 2006-01-31 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 Structures of the carbohydrate recognition domain of Ca2+-independent cargo receptors Emp46p and Emp47p. J.Biol.Chem., 281, 2006
3ITU	hPDE2A catalytic domain complexed with IBMX 分子名称: 3-ISOBUTYL-1-METHYLXANTHINE, MAGNESIUM ION, ZINC ION, ... 著者 Pandit, J. 登録日 2009-08-28 公開日 2009-10-27 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.58 Å) 主引用文献 Mechanism for the allosteric regulation of phosphodiesterase 2A deduced from the X-ray structure of a near full-length construct. Proc.Natl.Acad.Sci.USA, 106, 2009
4FON	High Energy Remote SAD structure solution of Proteinase K from the 37.8 keV Tellurium K edge 分子名称: 1,2-ETHANEDIOL, CALCIUM ION, OXYGEN ATOM, ... 著者 Jakoncic, J. 登録日 2012-06-20 公開日 2012-08-22 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.05 Å) 主引用文献 Macromolecular Crystallography at High(er) Energy To be Published
4BFS	Crystal structure of Mycobacterium tuberculosis PanK in complex with a triazole inhibitory compound (1a) 分子名称: N-[1-(5-{[2-(4-FLUOROPHENOXY)ETHYL]SULFANYL}-4-METHYL-4H-1,2,4-TRIAZOL-3-YL)ETHYL]-2-(TRIFLUOROMETHYL)BENZAMIDE, PANTOTHENATE KINASE 著者 Bjorkelid, C, Bergfors, T, Jones, T.A. 登録日 2013-03-22 公開日 2013-05-15 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural and Biochemical Characterization of Compounds Inhibiting Mycobacterium Tuberculosis Pank J.Biol.Chem., 288, 2013
4NST	Crystal structure of human Cdk12/Cyclin K in complex with ADP-aluminum fluoride 分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, ... 著者 Boesken, C.A, Farnung, L, Anand, K, Geyer, M. 登録日 2013-11-29 公開日 2014-03-26 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The structure and substrate specificity of human Cdk12/Cyclin K. Nat Commun, 5, 2014
3IWE	Crystal Structure of human type-I N-myristoyltransferase with bound myristoyl-CoA and inhibitor DDD85646 分子名称: 2,6-dichloro-4-(2-piperazin-1-ylpyridin-4-yl)-N-(1,3,5-trimethyl-1H-pyrazol-4-yl)benzenesulfonamide, Glycylpeptide N-tetradecanoyltransferase 1, TETRADECANOYL-COA 著者 Qiu, W, Hutchinson, A, Wernimont, A, Lin, Y.-H, Kania, A, Ravichandran, M, Kozieradzki, I, Cossar, D, Schapira, M, Arrowsmith, C.H, Bountra, C, Weigelt, J, Edwards, A.M, Wyatt, P.G, Ferguson, M.A.J, Frearson, J.A, Brand, S.Y, Robinson, D.A, Bochkarev, A, Hui, R, Structural Genomics Consortium (SGC) 登録日 2009-09-02 公開日 2009-09-15 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 Crystal Structure of human type-I N-myristoyltransferase with bound myristoyl-CoA and inhibitor DDD85646 To be Published
4YQ1	Crystal structure of TrmD, a M1G37 tRNA Methyltransferase with SAM-competitive compounds 分子名称: N-(1-{[(3-tert-butylbenzoyl)amino]methyl}cyclohexyl)-2,1-benzoxazole-4-carboxamide, tRNA (guanine-N(1)-)-methyltransferase 著者 Elkins, P.A, Bonnette, W.G, Madauss, K.P, Stuckey, J.A. 登録日 2015-03-13 公開日 2016-03-16 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 To Be Published To be published
4FRZ	Arabidopsis KCBP motor domain dimerized via regulatory domain 分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, IMIDAZOLE, ... 著者 Vinogradova, M. 登録日 2012-06-26 公開日 2013-07-10 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Plant Kinesin-Like Calmodulin Binding Protein Employs Its Regulatory Domain for Dimerization. Plos One, 8, 2013
3WK8	Crystal structure of soluble epoxide hydrolase in complex with fragment inhibitor 分子名称: 6-(trifluoromethyl)-1,3-benzothiazol-2-amine, Bifunctional epoxide hydrolase 2, MAGNESIUM ION, ... 著者 Amano, Y, Yamaguchi, T, Tanabe, E. 登録日 2013-10-17 公開日 2014-04-16 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural insights into binding of inhibitors to soluble epoxide hydrolase gained by fragment screening and X-ray crystallography. Bioorg.Med.Chem., 22, 2014
4YQR	Crystal structure of TrmD, a M1G37 tRNA Methyltransferase with SAM-competitive compounds 分子名称: (4-amino-1,2,5-oxadiazol-3-yl)(4-methylpiperazin-1-yl)methanone, tRNA (guanine-N(1)-)-methyltransferase 著者 Elkins, P.A, Bonnette, W.G, Stuckey, J.A. 登録日 2015-03-13 公開日 2016-03-16 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.701 Å) 主引用文献 Crystal structure of TrmD, a M1G37 tRNA Methyltransferase with SAM-competitive compounds To Be Published

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