PDB: 222415 件ウェブページステータス検索Chemie searchBIRD

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4LS8	Crystal structure of Bacillus subtilis beta-ketoacyl-ACP synthase II (FabF) in a covalent complex with cerulenin 分子名称: (3R,7E,10E)-3-hydroxy-4-oxododeca-7,10-dienamide, 1,2-ETHANEDIOL, 3-oxoacyl-[acyl-carrier-protein] synthase 2, ... 著者 Trajtenberg, F, Larrieux, N, Buschiazzo, A. 登録日 2013-07-22 公開日 2014-04-02 最終更新日 2014-06-04 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural insights into bacterial resistance to cerulenin. Febs J., 281, 2014
4M19	dihydrodipicolinate synthase from C. jejuni with pyruvate bound to the active site and Lysine bound to allosteric site 分子名称: 1,2-ETHANEDIOL, 4-hydroxy-tetrahydrodipicolinate synthase, DI(HYDROXYETHYL)ETHER, ... 著者 Conly, C.J.T. 登録日 2013-08-02 公開日 2015-01-14 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Tyrosine 110 Plays a Critical Role in Regulating the Allosteric Inhibition of Campylobacter jejuni Dihydrodipicolinate Synthase by Lysine. Biochemistry, 53, 2014
4D8K	Crystal structure of a SH3-SH2 domains of a lymphocyte-specific protein tyrosine kinase (LCK) from Homo sapiens at 2.36 A resolution 分子名称: GLYCEROL, SULFATE ION, Tyrosine-protein kinase Lck 著者 Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL) 登録日 2012-01-10 公開日 2012-01-25 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.36 Å) 主引用文献 Crystal structure of a SH3-SH2 domains of a lymphocyte-specific protein tyrosine kinase (LCK) from Homo sapiens at 2.36 A resolution To be published
4M1Y	Crystal Structure of small molecule vinylsulfonamide 15 covalently bound to K-Ras G12C 分子名称: GUANOSINE-5'-DIPHOSPHATE, K-Ras GTPase, N-{1-[N-(5,7-dichloro-2,1,3-benzothiadiazol-4-yl)glycyl]piperidin-4-yl}ethanesulfonamide 著者 Ostrem, J.M, Peters, U, Sos, M.L, Wells, J.A, Shokat, K.M. 登録日 2013-08-04 公開日 2013-11-27 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.491 Å) 主引用文献 K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions. Nature, 503, 2013
4M3F	Rapid and efficient design of new inhibitors of Mycobacterium tuberculosis transcriptional repressor EthR using fragment growing, merging and linking approaches 分子名称: HTH-type transcriptional regulator EthR, N-(3-methylbutyl)-4-(2-methyl-1,3-thiazol-4-yl)benzenesulfonamide 著者 Villemagne, B, Flipo, M, Blondiaux, N, Crauste, C, Malaquin, S, Leroux, F, Piveteau, C, Villeret, V, Brodin, P, Villoutreix, B, Sperandio, O, Wohlkonig, A, Wintjens, R, Deprez, B, Baulard, A, Willand, N. 登録日 2013-08-06 公開日 2014-06-25 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Ligand Efficiency Driven Design of New Inhibitors of Mycobacterium tuberculosis Transcriptional Repressor EthR Using Fragment Growing, Merging, and Linking Approaches. J.Med.Chem., 57, 2014
4M84	Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with inhibitor UW1455 分子名称: 5-amino-1-tert-butyl-3-(quinolin-2-yl)-1H-pyrazole-4-carboxamide, Calmodulin-domain protein kinase 1 著者 Merritt, E.A. 登録日 2013-08-12 公開日 2013-10-02 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.998 Å) 主引用文献 Potent and selective inhibitors of CDPK1 from T. gondii and C. parvum based on a 5-aminopyrazole-4-carboxamide scaffold. ACS Med Chem Lett, 5, 2014
4MB7	Crystal Structure of a viral DNA glycosylase 分子名称: Endonuclease 8-like L720, SULFATE ION, ZINC ION 著者 Prakash, A, Eckenroth, B.E, Doublie, S. 登録日 2013-08-19 公開日 2013-10-30 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 Structural investigation of a viral ortholog of human NEIL2/3 DNA glycosylases. Dna Repair, 12, 2013
4D8G	Chlamydia trachomatis NrdB with a Mn/Fe cofactor (procedure 2 - low Mn) 分子名称: FE (III) ION, MANGANESE (II) ION, Ribonucleoside-diphosphate reductase subunit beta 著者 Dassama, L.M.K, Boal, A.K, Krebs, C, Rosenzweig, A.C, Bollinger Jr, J.M. 登録日 2012-01-10 公開日 2012-02-15 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Evidence that the beta subunit of Chlamydia trachomatis ribonucleotide reductase is active with the manganese ion of its manganese(IV)/iron(III) cofactor in site 1. J.Am.Chem.Soc., 134, 2012
4MGT	ALKBH2 R110A cross-linked to undamaged dsDNA 分子名称: Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2, DNA1, DNA2, ... 著者 Chen, B, Gan, J, Yang, C.G. 登録日 2013-08-28 公開日 2014-02-26 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 The complex structures of ALKBH2 mutants cross-linked to dsDNA reveal the conformational swing of β-hairpin Sci China Chem, 57, 2014
4MHG	Crystal structure of ETV6 bound to a specific DNA sequence 分子名称: Complementary Specific 14 bp DNA, Specific 14 bp DNA, Transcription factor ETV6 著者 Chan, A.C, De, S, Coyne III, H.J, Okon, M, Murphy, M.E, Graves, B.J, McIntosh, L.P. 登録日 2013-08-29 公開日 2014-01-08 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.199 Å) 主引用文献 Steric Mechanism of Auto-Inhibitory Regulation of Specific and Non-Specific DNA Binding by the ETS Transcriptional Repressor ETV6. J.Mol.Biol., 426, 2014
4LSU	Crystal structure of broadly and potently neutralizing antibody VRC-PG20 in complex with HIV-1 clade A/E 93TH057 gp120 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... 著者 Zhou, T, Moquin, S, Kwong, P.D. 登録日 2013-07-23 公開日 2013-08-21 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Multidonor Analysis Reveals Structural Elements, Genetic Determinants, and Maturation Pathway for HIV-1 Neutralization by VRC01-Class Antibodies. Immunity, 39, 2013
4LUE	Crystal Structure of HCK in complex with 7-[trans-4-(4-methylpiperazin-1-yl)cyclohexyl]-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (resulting from displacement of SKF86002) 分子名称: 7-[trans-4-(4-methylpiperazin-1-yl)cyclohexyl]-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine, CALCIUM ION, CHLORIDE ION, ... 著者 Parker, L.J, Tanaka, A, Handa, N, Honda, K, Tomabechi, Y, Shirouzu, M, Yokoyama, S. 登録日 2013-07-25 公開日 2014-02-12 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (3.04 Å) 主引用文献 Kinase crystal identification and ATP-competitive inhibitor screening using the fluorescent ligand SKF86002. Acta Crystallogr.,Sect.D, 70, 2014
4MAX	Crystal structure of Synechococcus sp. PCC 7002 globin at cryogenic temperature with heme modification 分子名称: HEME B/C, SULFATE ION, cyanoglobin 著者 Wenke, B.B, Schlessman, J.L, Heroux, A, Lecomte, J.T.J. 登録日 2013-08-18 公開日 2013-08-28 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.444 Å) 主引用文献 The 2/2 hemoglobin from the cyanobacterium Synechococcus sp. PCC 7002 with covalently attached heme: Comparison of X-ray and NMR structures. Proteins, 82, 2014
4LY6	Nucleotide-induced asymmetry within ATPase activator ring drives s54-RNAP interaction and ATP hydrolysis 分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Transcriptional regulator (NtrC family), ... 著者 Sysoeva, T.A, Chowdhury, S, Guo, L, Nixon, B.T. 登録日 2013-07-30 公開日 2013-12-04 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 Nucleotide-induced asymmetry within ATPase activator ring drives sigma 54-RNAP interaction and ATP hydrolysis. Genes Dev., 27, 2013
4MD9	Crystal Structure of symmetric CK2 holoenzyme with mutated alpha subunit (F121E truncated at aa 336) 分子名称: Casein kinase II subunit alpha, Casein kinase II subunit beta, ZINC ION 著者 Lolli, G, Ranchio, A, Battistutta, R. 登録日 2013-08-22 公開日 2013-11-20 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Active Form of the Protein Kinase CK2 alpha 2 beta 2 Holoenzyme Is a Strong Complex with Symmetric Architecture. Acs Chem.Biol., 9, 2014
4LCB	Structure of Vps4 homolog from Acidianus hospitalis 分子名称: CHLORIDE ION, Cell division protein CdvC, Vps4 著者 Han, H, Hill, C.P, Whitby, F.G, Monroe, N. 登録日 2013-06-21 公開日 2013-11-06 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.08 Å) 主引用文献 The Oligomeric State of the Active Vps4 AAA ATPase. J.Mol.Biol., 426, 2014
4KUE	Crystal structure of 3-hydroxybutylryl-CoA dehydrogenase from Clostridium butyricum 分子名称: 3-hydroxybutyryl-CoA dehydrogenase 著者 Kim, E.J, Kim, S, Kim, K.J. 登録日 2013-05-22 公開日 2014-05-28 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of (S)-3-hydroxybutylryl-CoA dehydrogenase form the n-butanol sysnthesizing bacterium, Clostridium butyricum to be published
4KV2	Ubiquitin-like domain of the mycobacterium tuberculosis type VII secretion system protein ECCD1 分子名称: ESX-1 secretion system protein eccD1 著者 Korotkov, K.V, Evans, T.J. 登録日 2013-05-22 公開日 2014-04-09 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Structures of EccB1 and EccD1 from the core complex of the mycobacterial ESX-1 type VII secretion system. Bmc Struct.Biol., 16, 2016
4KW9	Crystal Structure of Green Fluorescent Protein 分子名称: CHLORIDE ION, Green fluorescent protein, ZINC ION 著者 Barnard, T.J, Yu, X, Noinaj, N, Taraska, J.W. 登録日 2013-05-23 公開日 2014-04-09 最終更新日 2022-12-21 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal Structure of Green Fluorescent Protein To be Published
4KWI	The crystal structure of angucycline C-6 ketoreductase LanV with bound NADP and 11-deoxy-6-oxylandomycinone 分子名称: 1,8-dihydroxy-3-methyltetraphene-6,7,12(5H)-trione, DI(HYDROXYETHYL)ETHER, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... 著者 Paananen, P, Patrikainen, P, Mantsala, P, Niemi, J, Niiranen, L, Metsa-Ketela, M. 登録日 2013-05-24 公開日 2013-07-31 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural and functional analysis of angucycline C-6 ketoreductase LanV involved in landomycin biosynthesis. Biochemistry, 52, 2013
4KWT	Crystal structure of unliganded anabolic ornithine carbamoyltransferase from Vibrio vulnificus at 1.86 A resolution 分子名称: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, Ornithine carbamoyltransferase 著者 Shabalin, I.G, Bacal, P, Bajor, J, Winsor, J, Grimshaw, S, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2013-05-24 公開日 2013-06-05 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Crystal structures and kinetic properties of anabolic ornithine carbamoyltransferase from human pathogens Vibrio vulnificus and Bacillus anthracis To be Published
4KYA	Crystal structure of non-classical TS inhibitor 3 in complex with Toxoplasma gondii TS-DHFR 分子名称: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 2-Amino-5-(1-naphthylsulfanyl)-3,9-dihydro-4H-pyrimido[4,5-b]indol-4-one, Bifunctional dihydrofolate reductase-thymidylate synthase, ... 著者 Sharma, H, Anderson, K.S. 登録日 2013-05-28 公開日 2014-08-06 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.263 Å) 主引用文献 Discovery of potent and selective inhibitors of Toxoplasma gondii thymidylate synthase for opportunistic infections. ACS Med Chem Lett, 4, 2013
4L2W	Crystal structure of the Shroom-Binding domain of human Rock1 分子名称: Rho-associated protein kinase 1 著者 Mohan, S, VanDemark, A.P. 登録日 2013-06-04 公開日 2014-04-16 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.49 Å) 主引用文献 Structure of a highly conserved domain of Rock1 required for Shroom-mediated regulation of cell morphology. Plos One, 8, 2013
4L4S	Structural characterisation of the NADH binary complex of human lactate dehydrogenase M isozyme 分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, L-lactate dehydrogenase A chain 著者 Dempster, S, Harper, S, Moses, J.E, Dreveny, I. 登録日 2013-06-09 公開日 2014-04-30 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural characterization of the apo form and NADH binary complex of human lactate dehydrogenase. Acta Crystallogr.,Sect.D, 70, 2014
4L5C	Methylthioadenosine phosphorylase from Schistosoma mansoni in complex with adenine in space group P212121 分子名称: ADENINE, GLYCEROL, S-methyl-5'-thioadenosine phosphorylase 著者 Torini, J.R, DeMarco, R, Brandao-Neto, J, Pereira, H.M. 登録日 2013-06-10 公開日 2014-06-11 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.075 Å) 主引用文献 Crystal Structure of Schistosoma mansoni Adenosine Phosphorylase/5'-Methylthioadenosine Phosphorylase and Its Importance on Adenosine Salvage Pathway. Plos Negl Trop Dis, 10, 2016

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