4LY6

Nucleotide-induced asymmetry within ATPase activator ring drives s54-RNAP interaction and ATP hydrolysis

Summary for 4LY6

• Entry DOI: 10.2210/pdb4ly6/pdb
• Related: 4LZZ
• Descriptor: Transcriptional regulator (NtrC family), [[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-tris(fluoranyl)beryllium, MAGNESIUM ION, ... (4 entities in total)
• Functional Keywords: aaa+ atpase, bacterial enhancer binding protein, s54-dependent transcription activator, molecular machine, sigma54, s54-rnap, transcription regulator
• Biological source: Aquifex aeolicus
• Total number of polymer chains: 24
• Total formula weight: 748742.87

Authors

Sysoeva, T.A.,Chowdhury, S.,Guo, L.,Nixon, B.T. (deposition date: 2013-07-30, release date: 2013-12-04, Last modification date: 2024-02-28)

• Primary citation: Sysoeva, T.A.,Chowdhury, S.,Guo, L.,Nixon, B.T.; Nucleotide-induced asymmetry within ATPase activator ring drives sigma 54-RNAP interaction and ATP hydrolysis.; Genes Dev., 27:2500-2511, 2013; PubMed: 24240239; DOI: 10.1101/gad.229385.113

Experimental method

X-RAY DIFFRACTION (3.6 Å)