4D8K
Crystal structure of a SH3-SH2 domains of a lymphocyte-specific protein tyrosine kinase (LCK) from Homo sapiens at 2.36 A resolution
Summary for 4D8K
Entry DOI | 10.2210/pdb4d8k/pdb |
Descriptor | Tyrosine-protein kinase Lck, SULFATE ION, GLYCEROL, ... (4 entities in total) |
Functional Keywords | protein kinases, sh2 domain, sh3 domain, structural genomics, joint center for structural genomics, jcsg, protein structure initiative, psi-biology, partnership for t-cell biology, tcell, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm : P06239 |
Total number of polymer chains | 1 |
Total formula weight | 19866.92 |
Authors | Joint Center for Structural Genomics (JCSG),Partnership for T-Cell Biology (TCELL) (deposition date: 2012-01-10, release date: 2012-01-25, Last modification date: 2024-05-22) |
Primary citation | Joint Center for Structural Genomics (JCSG),Partnership for T-Cell Biology Crystal structure of a SH3-SH2 domains of a lymphocyte-specific protein tyrosine kinase (LCK) from Homo sapiens at 2.36 A resolution To be published, |
Experimental method | X-RAY DIFFRACTION (2.36 Å) |
Structure validation
Download full validation report