4D8K
Crystal structure of a SH3-SH2 domains of a lymphocyte-specific protein tyrosine kinase (LCK) from Homo sapiens at 2.36 A resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Tyrosine-protein kinase Lck | polymer | 175 | 19586.7 | 1 | UniProt (P06239) Pfam (PF00018) Pfam (PF00017) | Homo sapiens (human) | Leukocyte C-terminal Src kinase, LSK, Lymphocyte cell-specific protein-tyrosine kinase, Protein YT16, Proto-oncogene Lck, T cell-specific protein-tyrosine kinase, p56-LCK |
| 2 | B (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 3 | C, D (A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 4 | E (A) | water | water | 18.0 | 43 | Chemie (HOH) |
Sequence modifications
A: 53 - 226 (UniProt: P06239)
| PDB | External Database | Details |
|---|---|---|
| Gly 52 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 19586.7 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 280.3 | |
| All* | Total formula weight | 19866.9 |
