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8PDA
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BU of 8pda by Molmil
cryo-EM structure of Doa10 with RING domain in MSP1E3D1
分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHATE, ERAD-associated E3 ubiquitin-protein ligase DOA10
著者Botsch, J.J, Braeuning, B, Schulman, B.A.
登録日2023-06-12
公開日2024-01-17
実験手法ELECTRON MICROSCOPY (3.58 Å)
主引用文献Doa10/MARCH6 architecture interconnects E3 ligase activity with lipid-binding transmembrane channel to regulate SQLE.
Nat Commun, 15, 2024
8OOQ
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BU of 8ooq by Molmil
Glutamine synthetase from Methanothermococcus thermolithotrophicus in complex with 2-oxoglutarate and Mg at 2.91 A resolution
分子名称: 1,2-ETHANEDIOL, 2-OXOGLUTARIC ACID, DI(HYDROXYETHYL)ETHER, ...
著者Mueller, M.-C, Wagner, T.
登録日2023-04-05
公開日2024-01-24
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.91 Å)
主引用文献Differences in regulation mechanisms of glutamine synthetases from methanogenic archaea unveiled by structural investigations.
Commun Biol, 7, 2024
6D4L
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BU of 6d4l by Molmil
Joint X-ray/neutron structure of DNA oligonucleotide d(GTGGCCAC)2 with 2'-SeCH3 modification on Cyt5
分子名称: DNA (5'-D(*GP*TP*GP*GP*(CSL)P*CP*AP*C)-3'), MAGNESIUM ION
著者Kovalevsky, A, Huang, Z, Vandavasi, V.G.
登録日2018-04-18
公開日2018-10-17
最終更新日2023-10-04
実験手法NEUTRON DIFFRACTION (1.56 Å), X-RAY DIFFRACTION
主引用文献Temperature-Induced Replacement of Phosphate Proton with Metal Ion Captured in Neutron Structures of A-DNA.
Structure, 26, 2018
8OWD
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BU of 8owd by Molmil
Lipidic amyloid-beta(1-40) fibril - polymorph L3
分子名称: Amyloid-beta A4 protein
著者Frieg, B, Han, M, Giller, K, Dienemann, C, Riedel, D, Becker, S, Andreas, L.B, Griesinger, C, Schroeder, G.F.
登録日2023-04-27
公開日2024-03-06
実験手法ELECTRON MICROSCOPY (3.28 Å)
主引用文献Cryo-EM structures of lipidic fibrils of amyloid-beta (1-40).
Nat Commun, 15, 2024
8OVK
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BU of 8ovk by Molmil
Lipidic amyloid-beta(1-40) fibril - polymorph L1
分子名称: Amyloid-beta A4 protein
著者Frieg, B, Han, M, Giller, K, Dienemann, C, Riedel, D, Becker, S, Andreas, L.B, Griesinger, C, Schroeder, G.F.
登録日2023-04-26
公開日2024-03-06
実験手法ELECTRON MICROSCOPY (2.88 Å)
主引用文献Cryo-EM structures of lipidic fibrils of amyloid-beta (1-40).
Nat Commun, 15, 2024
8OWJ
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BU of 8owj by Molmil
Lipidic amyloid-beta(1-40) fibril - polymorph L2-L2
分子名称: Amyloid-beta A4 protein
著者Frieg, B, Han, M, Giller, K, Dienemann, C, Riedel, D, Becker, S, Andreas, L.B, Griesinger, C, Schroeder, G.F.
登録日2023-04-28
公開日2024-03-06
実験手法ELECTRON MICROSCOPY (3.75 Å)
主引用文献Cryo-EM structures of lipidic fibrils of amyloid-beta (1-40).
Nat Commun, 15, 2024
8OVM
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BU of 8ovm by Molmil
Lipidic amyloid-beta(1-40) fibril - polymorph L2
分子名称: Amyloid-beta A4 protein
著者Frieg, B, Han, M, Giller, K, Dienemann, C, Riedel, D, Becker, S, Andreas, L.B, Griesinger, C, Schroeder, G.F.
登録日2023-04-26
公開日2024-03-06
実験手法ELECTRON MICROSCOPY (3.24 Å)
主引用文献Cryo-EM structures of lipidic fibrils of amyloid-beta (1-40).
Nat Commun, 15, 2024
8OWE
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BU of 8owe by Molmil
Lipidic amyloid-beta(1-40) fibril - polymorph L2-L3
分子名称: Amyloid-beta A4 protein
著者Frieg, B, Han, M, Giller, K, Dienemann, C, Riedel, D, Becker, S, Andreas, L.B, Griesinger, C, Schroeder, G.F.
登録日2023-04-27
公開日2024-03-06
実験手法ELECTRON MICROSCOPY (3.75 Å)
主引用文献Cryo-EM structures of lipidic fibrils of amyloid-beta (1-40).
Nat Commun, 15, 2024
8OWK
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BU of 8owk by Molmil
Lipidic amyloid-beta(1-40) fibril - polymorph L3-L3
分子名称: Amyloid-beta A4 protein
著者Frieg, B, Han, M, Giller, K, Dienemann, C, Riedel, D, Becker, S, Andreas, L.B, Griesinger, C, Schroeder, G.F.
登録日2023-04-28
公開日2024-03-06
実験手法ELECTRON MICROSCOPY (3.86 Å)
主引用文献Cryo-EM structures of lipidic fibrils of amyloid-beta (1-40).
Nat Commun, 15, 2024
6UH9
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BU of 6uh9 by Molmil
Crystal structure of DAD2 D166A mutant
分子名称: Decreased Apical Dominance 2, TETRAETHYLENE GLYCOL
著者Sharma, P, Hamiaux, C, Snowden, K.C.
登録日2019-09-27
公開日2020-02-26
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.52 Å)
主引用文献Flexibility of the petunia strigolactone receptor DAD2 promotes its interaction with signaling partners.
J.Biol.Chem., 295, 2020
6WK0
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BU of 6wk0 by Molmil
Crystal structure of human ribokinase in complex with AMPPCP and ribose
分子名称: PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, Ribokinase, SODIUM ION, ...
著者Park, J.
登録日2020-04-15
公開日2021-04-21
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structures of human ribokinase
To Be Published
6D54
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BU of 6d54 by Molmil
Low Temperature joint X-ray/neutron structure of DNA oligonucleotide d(GTGGCCAC)2 with 2'-SeCH3 modification on Cyt5
分子名称: DNA (5'-D(*GP*TP*GP*GP*(CSL)P*CP*AP*C)-3'), MAGNESIUM ION
著者Kovalevsky, A, Huang, Z, Vandavasi, V.G.
登録日2018-04-19
公開日2018-10-17
最終更新日2023-10-04
実験手法NEUTRON DIFFRACTION (1.65 Å), X-RAY DIFFRACTION
主引用文献Temperature-Induced Replacement of Phosphate Proton with Metal Ion Captured in Neutron Structures of A-DNA.
Structure, 26, 2018
8Q7R
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BU of 8q7r by Molmil
Ubiquitin ligation to substrate by a cullin-RING E3 ligase & Cdc34: NEDD8-CUL2-RBX1-ELOB/C-FEM1C with trapped UBE2R2~donor UB-Sil1 peptide
分子名称: 5-azanyl-1-oxidanyl-pentan-2-one, Cullin-2, E3 ubiquitin-protein ligase RBX1, ...
著者Liwocha, J, Prabu, J.R, Kleiger, G, Schulman, B.A.
登録日2023-08-16
公開日2024-02-21
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (3.71 Å)
主引用文献Cullin-RING ligases employ geometrically optimized catalytic partners for substrate targeting.
Mol.Cell, 84, 2024
8Q5W
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BU of 8q5w by Molmil
MgADP-bound Fe protein of the molybdenum nitrogenase from Methanocaldococcus infernus
分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ...
著者Maslac, N, Wagner, T.
登録日2023-08-09
公開日2024-05-15
最終更新日2024-08-14
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Structural comparison of (hyper-)thermophilic nitrogenase reductases from three marine Methanococcales.
Febs J., 291, 2024
8PRW
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BU of 8prw by Molmil
Cryo-EM structure of the yeast fatty acid synthase at 1.9 angstrom resolution
分子名称: 1-DEOXY-1-(7,8-DIMETHYL-2,4-DIOXO-3,4-DIHYDRO-2H-BENZO[G]PTERIDIN-1-ID-10(5H)-YL)-5-O-PHOSPHONATO-D-RIBITOL, COENZYME A, Fatty acid synthase subunit alpha, ...
著者Singh, K, Bunzel, G, Graf, B, Yip, K.M, Stark, H, Chari, A.
登録日2023-07-12
公開日2023-11-22
実験手法ELECTRON MICROSCOPY (1.9 Å)
主引用文献Reconstruction of a fatty acid synthesis cycle from acyl carrier protein and cofactor structural snapshots.
Cell, 186, 2023
8PN8
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BU of 8pn8 by Molmil
Engineered glycolyl-CoA carboxylase (L100N variant) with bound CoA
分子名称: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, COENZYME A, Propionyl-CoA carboxylase alpha subunit, ...
著者Zarzycki, J, Marchal, D.G, Schulz, L, Prinz, S, Erb, T.J.
登録日2023-06-30
公開日2023-11-29
最終更新日2023-12-27
実験手法ELECTRON MICROSCOPY (2.31 Å)
主引用文献Machine Learning-Supported Enzyme Engineering toward Improved CO 2 -Fixation of Glycolyl-CoA Carboxylase.
Acs Synth Biol, 12, 2023
8Q9T
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BU of 8q9t by Molmil
CryoEM structure of a S. Cerevisiae Ski238 complex bound to RNA
分子名称: Antiviral helicase SKI2, Antiviral protein SKI8, RNA (5'-R(P*UP*UP*UP*U)-3'), ...
著者Keidel, A, Koegel, A, Reichelt, P, Kowalinski, E, Schaefer, I.B, Conti, E.
登録日2023-08-21
公開日2023-11-29
実験手法ELECTRON MICROSCOPY (2.84 Å)
主引用文献Concerted structural rearrangements enable RNA channeling into the cytoplasmic Ski238-Ski7-exosome assembly.
Mol.Cell, 83, 2023
8QB3
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BU of 8qb3 by Molmil
ADDobody zinc containing condition
分子名称: ADDobody, ZINC ION
著者Buzas, D, Toelzer, C, Berger, I, Schaffitzel, C.
登録日2023-08-24
公開日2023-12-27
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Engineering the ADDobody protein scaffold for generation of high-avidity ADDomer super-binders.
Structure, 32, 2024
8Q7S
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BU of 8q7s by Molmil
Crystal structure of the SARS-CoV-2 RBD (Wuhan) with neutralizing VHHs Ma6F06 and Re21H01
分子名称: 1,2-ETHANEDIOL, 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, GLYCEROL, ...
著者Guttler, T, Aksu, M, Gorlich, D.
登録日2023-08-16
公開日2023-12-20
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Nanobodies to multiple spike variants and inhalation of nanobody-containing aerosols neutralize SARS-CoV-2 in cell culture and hamsters.
Antiviral Res., 221, 2023
8QBX
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BU of 8qbx by Molmil
Chimeric Adenovirus-derived dodecamer
分子名称: Penton protein
著者Buzas, D, Borucu, U, Bufton, J, Kapadalakere, S.Y, Toelzer, C.
登録日2023-08-25
公開日2023-12-27
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (2.2 Å)
主引用文献Engineering the ADDobody protein scaffold for generation of high-avidity ADDomer super-binders.
Structure, 32, 2024
8PJN
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BU of 8pjn by Molmil
Catalytic module of human CTLH E3 ligase bound to multiphosphorylated UBE2H~ubiquitin
分子名称: E3 ubiquitin-protein transferase MAEA, E3 ubiquitin-protein transferase RMND5A, Ubiquitin, ...
著者Chrustowicz, J, Sherpa, D, Prabu, R.J, Schulman, B.A.
登録日2023-06-23
公開日2024-01-03
最終更新日2024-01-31
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Multisite phosphorylation dictates selective E2-E3 pairing as revealed by Ubc8/UBE2H-GID/CTLH assemblies.
Mol.Cell, 84, 2024
8PMQ
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BU of 8pmq by Molmil
Catalytic module of yeast GID E3 ligase bound to multiphosphorylated Ubc8~ubiquitin
分子名称: E3 ubiquitin-protein ligase RMD5, Protein FYV10, Ubiquitin, ...
著者Chrustowicz, J, Sherpa, D, Prabu, R.J, Schulman, B.A.
登録日2023-06-29
公開日2024-01-03
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (3.53 Å)
主引用文献Multisite phosphorylation dictates selective E2-E3 pairing as revealed by Ubc8/UBE2H-GID/CTLH assemblies.
Mol.Cell, 84, 2024
8QCF
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BU of 8qcf by Molmil
yeast cytoplasmic exosome-Ski2 complex degrading a RNA substrate
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Antiviral helicase SKI2, Exosome complex component CSL4, ...
著者Keidel, A, Koegel, A, Reichelt, P, Kowalinski, E, Schaefer, I.B, Conti, E.
登録日2023-08-25
公開日2024-01-10
実験手法ELECTRON MICROSCOPY (2.55 Å)
主引用文献Concerted structural rearrangements enable RNA channeling into the cytoplasmic Ski238-Ski7-exosome assembly.
Mol.Cell, 83, 2023
8Q0N
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BU of 8q0n by Molmil
HACE1 in complex with RAC1 Q61L
分子名称: E3 ubiquitin-protein ligase HACE1, GUANOSINE-5'-TRIPHOSPHATE, Ras-related C3 botulinum toxin substrate 1, ...
著者Wolter, M, Duering, J, Dienemann, C, Lorenz, S.
登録日2023-07-28
公開日2024-01-10
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Structural mechanisms of autoinhibition and substrate recognition by the ubiquitin ligase HACE1.
Nat.Struct.Mol.Biol., 31, 2024
8PWL
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BU of 8pwl by Molmil
Cryo-EM structure of a full-length HACE1 dimer
分子名称: E3 ubiquitin-protein ligase HACE1
著者Duering, J, Wolter, M, Dienemann, C, Lorenz, S.
登録日2023-07-20
公開日2024-01-10
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (4.73 Å)
主引用文献Structural mechanisms of autoinhibition and substrate recognition by the ubiquitin ligase HACE1.
Nat.Struct.Mol.Biol., 31, 2024

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件を2024-08-14に公開中

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