PDB: 10530 件ウェブページステータス検索Chemie searchBIRD

---

1QL9	FACTOR XA SPECIFIC INHIBITOR IN COMPLEX WITH RAT TRYPSIN MUTANT X99RT 分子名称: CALCIUM ION, SULFATE ION, TRYPSIN, ... 著者 Stubbs, M.T. 登録日 1999-08-24 公開日 2000-08-25 最終更新日 2017-07-05 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Reconstructing the Binding Site of Factor Xa in Trypsin Reveals Ligand-Induced Structural Plasticity J.Mol.Biol., 325, 2003
7EQC	Crystal structure of the mini-centralspindlin complex 分子名称: CYtoKinesis defect, Kinesin-like protein 著者 Chen, Z, Pan, H. 登録日 2021-05-01 公開日 2022-04-13 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Mechanistic insights into central spindle assembly mediated by the centralspindlin complex. Proc.Natl.Acad.Sci.USA, 118, 2021
5C8X	ZHD-Intermediate complex after ZHD crystal soaking in ZEN for 20min 分子名称: (1E,10S)-1-(3,5-dihydroxyphenyl)-10-hydroxyundec-1-en-6-one, GLYCEROL, POTASSIUM ION, ... 著者 Hu, X.-J, Qi, Q, Yang, W.-J. 登録日 2015-06-26 公開日 2016-06-29 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 A Case Study of Lactonase ZHD To Be Published
5C81	ZHD-Intermediate complex after ZHD crystal soaking in ZEN for 12min 分子名称: (1E,10S)-1-(3,5-dihydroxyphenyl)-10-hydroxyundec-1-en-6-one, FORMIC ACID, GLYCEROL, ... 著者 Hu, X.-J, Qi, Q, Yang, W.-J. 登録日 2015-06-25 公開日 2016-06-29 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 A Case Study of Lactonase ZHD To Be Published
5C7Y	ZHD-Intermediate complex after ZHD crystal soaking in ZEN for 9min 分子名称: (1E,10S)-1-(3,5-dihydroxyphenyl)-10-hydroxyundec-1-en-6-one, FORMIC ACID, GLYCEROL, ... 著者 Hu, X.-J, Qi, Q, Yang, W.-J. 登録日 2015-06-25 公開日 2016-06-29 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 A Case Study of Lactonase ZHD To Be Published
5XO8	Crystal structure of a novel ZEN lactonase mutant with ligand Z 分子名称: (3S,11E)-14,16-dihydroxy-3-methyl-3,4,5,6,9,10-hexahydro-1H-2-benzoxacyclotetradecine-1,7(8H)-dione, Lactonase for protein 著者 Zheng, Y.Y, Liu, W.T, Liu, W.D, Chen, C.C, Guo, R.T. 登録日 2017-05-27 公開日 2018-05-02 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Crystal Structure of a Mycoestrogen-Detoxifying Lactonase from Rhinocladiella mackenziei: Molecular Insight into ZHD Substrate Selectivity Acs Catalysis, 8, 2018
5XO7	Crystal structure of a novel ZEN lactonase mutant with ligand a 分子名称: (3S,7R,11E)-7,14,16-trihydroxy-3-methyl-3,4,5,6,7,8,9,10-octahydro-1H-2-benzoxacyclotetradecin-1-one, lactonase for protein 著者 Zheng, Y.Y, Liu, W.T, Liu, W.D, Chen, C.C, Guo, R.T. 登録日 2017-05-27 公開日 2018-05-02 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Crystal Structure of a Mycoestrogen-Detoxifying Lactonase from Rhinocladiella mackenziei: Molecular Insight into ZHD Substrate Selectivity Acs Catalysis, 8, 2018
5XO6	Crystal structure of a novel ZEN lactonase mutant 分子名称: PENTAETHYLENE GLYCOL, lactonase for protein 著者 Zheng, Y.Y, Liu, W.T, Liu, W.D, Chen, C.C, Guo, R.T. 登録日 2017-05-27 公開日 2018-05-02 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.38 Å) 主引用文献 Crystal Structure of a Mycoestrogen-Detoxifying Lactonase from Rhinocladiella mackenziei: Molecular Insight into ZHD Substrate Selectivity Acs Catalysis, 8, 2018
3HH6	New azaborine compounds bind to the T4 lysozyme L99A cavity -ethylbenzene as control 分子名称: 2-HYDROXYETHYL DISULFIDE, Lysozyme, PHENYLETHANE, ... 著者 Liu, L, Matthews, B.W. 登録日 2009-05-14 公開日 2009-10-13 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 Boron mimetics: 1,2-dihydro-1,2-azaborines bind inside a nonpolar cavity of T4 lysozyme. Angew.Chem.Int.Ed.Engl., 48, 2009
5VXT	Crystal structure of catechol 1,2-dioxygenase from Burkholderia ambifaria 分子名称: 1,2-ETHANEDIOL, CATECHOL, CHLORIDE ION, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2017-05-24 公開日 2017-06-14 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Crystal structure of catechol 1,2-dioxygenase from Burkholderia ambifaria TO BE PUBLISHED
7LVK	Cfr-modified 50S subunit from Escherichia coli 分子名称: 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... 著者 Stojkovic, V, Myasnikov, A.G, Frost, A, Fujimori, D.G. 登録日 2021-02-25 公開日 2021-12-15 最終更新日 2023-11-15 実験手法 ELECTRON MICROSCOPY (2.2 Å) 主引用文献 Investigating antibiotic resistance of a ribosomal-RNA methylating enzyme through directed evolution To Be Published
7Q9O	Complex of Transthyretin with resveratrol exhibits multiple binding modes 分子名称: GLYCEROL, RESVERATROL, SODIUM ION, ... 著者 Derbyshire, D.J, Hammarstrom, P, von Castelmur, E, Begum, A. 登録日 2021-11-12 公開日 2022-11-23 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Transthyretin Binding Mode Dichotomy of Fluorescent trans -Stilbene Ligands. Acs Chem Neurosci, 14, 2023
7XJB	Rat-COMT, opicapone,SAM and Mg bond 分子名称: CHLORIDE ION, Catechol O-methyltransferase, MAGNESIUM ION, ... 著者 Takebe, K, Iijima, H, Suzuki, M, Kuwada-Kusunose, T. 登録日 2022-04-15 公開日 2023-05-31 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural and Computational Analyses of the Unique Interactions of Opicapone in the Binding Pocket of Catechol O -Methyltransferase: A Crystallographic Study and Fragment Molecular Orbital Analyses. J.Chem.Inf.Model., 63, 2023
7XUY	Crystal structure of 5-chloro-2-hydroxymuconate tautomerase CnbG 分子名称: Tautomerase 著者 Ma, H.L, Li, D.F. 登録日 2022-05-20 公開日 2023-03-29 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.001 Å) 主引用文献 Structural insights into the substrate specificity of 5-chloro-2-hydroxymuconate tautomerase CnbG. Biochem.Biophys.Res.Commun., 620, 2022
7YAC	Paltusotine-bound SSTR2-Gi complex 分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... 著者 Zhao, J, Shao, Z. 登録日 2022-06-27 公開日 2023-04-19 最終更新日 2023-09-27 実験手法 ELECTRON MICROSCOPY (3.24 Å) 主引用文献 Prospect of acromegaly therapy: molecular mechanism of clinical drugs octreotide and paltusotine. Nat Commun, 14, 2023
7S1G	wild-type Escherichia coli stalled ribosome with antibiotic linezolid 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Young, I.D, Stojkovic, V, Tsai, K, Lee, D.J, Fraser, J.S, Galonic Fujimori, D. 登録日 2021-09-02 公開日 2021-11-17 最終更新日 2023-11-15 実験手法 ELECTRON MICROSCOPY (2.48 Å) 主引用文献 Structural basis for context-specific inhibition of translation by oxazolidinone antibiotics. Nat.Struct.Mol.Biol., 29, 2022
7S1H	Wild-type Escherichia coli ribosome with antibiotic linezolid 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Young, I.D, Stojkovic, V, Tsai, K, Lee, D.J, Fraser, J.S, Galonic Fujimori, D. 登録日 2021-09-02 公開日 2021-11-17 最終更新日 2023-11-15 実験手法 ELECTRON MICROSCOPY (2.35 Å) 主引用文献 Structural basis for context-specific inhibition of translation by oxazolidinone antibiotics. Nat.Struct.Mol.Biol., 29, 2022
7RIV	human PXR LBD bound to GSK001 分子名称: Dabrafenib, Isoform 1C of Nuclear receptor subfamily 1 group I member 2 著者 Williams, S.P, Wisely, G.B, Ward, P. 登録日 2021-07-20 公開日 2021-08-25 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Overcoming the Pregnane X Receptor Liability: Rational Design to Eliminate PXR-Mediated CYP Induction. Acs Med.Chem.Lett., 12, 2021
4Z10	Inactive aurone synthase (polyphenol oxidase) co-crystallized with 1,4-resorcinol 分子名称: ACETATE ION, Aurone synthase, COPPER (II) ION, ... 著者 Molitor, C, Mauracher, S.G, Rompel, A. 登録日 2015-03-26 公開日 2016-04-06 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 Inactive aurone synthase (polyphenol oxidase) co-crystallized with 1,4-resorcinol To Be Published
8PI5	Crystal structure of human insulin desB30 precursor with an Alanine-Methionine-Lysine C-peptide in hexamer (T3R3) conformation 分子名称: CHLORIDE ION, Insulin B chain,Insulin A chain, RESORCINOL, ... 著者 Johansson, E, Schluckebier, G. 登録日 2023-06-21 公開日 2023-11-08 最終更新日 2024-04-17 実験手法 X-RAY DIFFRACTION (1.66 Å) 主引用文献 Molecular engineering of insulin for recombinant expression in yeast. Trends Biotechnol, 42, 2024
4QOO	Structure of Bacillus pumilus catalase with resorcinol bound. 分子名称: CHLORIDE ION, Catalase, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Loewen, P.C. 登録日 2014-06-20 公開日 2015-02-25 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Unprecedented access of phenolic substrates to the heme active site of a catalase: Substrate binding and peroxidase-like reactivity of Bacillus pumilus catalase monitored by X-ray crystallography and EPR spectroscopy. Proteins, 83, 2015
8PF2	Structure of the Histidine Kinase CheA ATP-Binding domain in complex with compound ODDHK16 分子名称: Chemotaxis protein CheA, RESORCINOL 著者 Adhav, A, Marina, A. 登録日 2023-06-15 公開日 2024-06-26 最終更新日 2024-07-10 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Repurposing Hsp90 inhibitors as antimicrobials targeting two-component systems identifies compounds leading to loss of bacterial membrane integrity. Microbiol Spectr, 2024
3ZU1	Structure of LysB29(Nepsilon omega-carboxyheptadecanoyl) des(B30) Human Insulin 分子名称: CHLORIDE ION, INSULIN A CHAIN, INSULIN B CHAIN, ... 著者 Schluckebier, G, Whittingham, J. 登録日 2011-07-13 公開日 2011-08-03 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structure of Lysb29(Nepsilon Omega-Carboxyheptadecanoyl) Des(B30) Human Insulin To be Published
4AJX	Ligand controlled assembly of hexamers, dihexamers, and linear multihexamer structures by an engineered acylated insulin 分子名称: IMIDAZOLE, INSULIN, N-(16-Carboxyhexadecanoyl)-L-glutamic acid, ... 著者 Steensgaard, D.B, Schluckebier, G, Strauss, H.M, Norrman, M, Thomsen, J.K, Friderichsen, A.V, Havelund, S, Jonassen, I. 登録日 2012-02-20 公開日 2013-01-09 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Ligand Controlled Assembly of Hexamers, Dihexamers, and Linear Multihexamer Structures by the Engineered Acylated Insulin Degludec. Biochemistry, 52, 2013
7XT0	Crystal structure of RNA helicase from Saint Louis encephalitis virus and discovery of its inhibitors 分子名称: 1,2-ETHANEDIOL, RNA helicase 著者 Wang, D.P, Jiang, F.Y, Zeng, X.Y, Zhao, R, Chen, C, Zhu, Y, Cao, J.M. 登録日 2022-05-15 公開日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.48 Å) 主引用文献 Crystal structure of RNA helicase from Saint Louis encephalitis virus and discovery of its inhibitors To Be Published

<224225226227228229230231232233234235236237238239>