5XO8

Crystal structure of a novel ZEN lactonase mutant with ligand Z

Summary for 5XO8

Entry DOI	10.2210/pdb5xo8/pdb
Related	5XO6 5XO7
Descriptor	Lactonase for protein, (3S,11E)-14,16-dihydroxy-3-methyl-3,4,5,6,9,10-hexahydro-1H-2-benzoxacyclotetradecine-1,7(8H)-dione (3 entities in total)
Functional Keywords	alpha/beta-hydrolase, lactonase, zearalenone, hydrolase
Biological source	Rhinocladiella mackenziei CBS 650.93
Total number of polymer chains	8
Total formula weight	238140.66
Authors	Zheng, Y.Y.,Liu, W.T.,Liu, W.D.,Chen, C.C.,Guo, R.T. (deposition date: 2017-05-27, release date: 2018-05-02, Last modification date: 2023-11-22)
Primary citation	Zheng, Y.Y.,Liu, W.T.,Chen, C.C.,Hu, X.Y.,Liu, W.D.,Ko, T.P.,Tang, X.K.,Wei, H.L.,Huang, J.W.,Guo, R.T. Crystal Structure of a Mycoestrogen-Detoxifying Lactonase from Rhinocladiella mackenziei: Molecular Insight into ZHD Substrate Selectivity Acs Catalysis, 8:4294-4298, 2018 Cited by DOI: 10.1021/acscatal.8b00464 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.88 Å)

Structure validation