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173D
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MULTIPLE BINDING MODES OF ANTICANCER DRUG ACTINOMYCIN D: X-RAY, MOLECULAR MODELING, AND SPECTROSCOPIC STUDIES OF D(GAAGCTTC)2-ACTINOMYCIN D COMPLEXES AND ITS HOST DNA
分子名称: ACTINOMYCIN D, DNA (5'-D(*GP*AP*AP*GP*CP*TP*TP*C)-3')
著者Kamitori, S, Takusagawa, F.
登録日1994-04-18
公開日1994-10-15
最終更新日2024-07-10
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Multiple Binding Modes of Anticancer Drug Actinomycin D: X-Ray, Molecular Modeling, and Spectroscopic Studies of D(Gaagcttc)2-Actinomycin D Complexes and its Host DNA
J.Am.Chem.Soc., 116, 1994
4RKG
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Structure of the MSL2 CXC domain bound with a non-specific (GC)6 DNA
分子名称: DNA (5'-D(*GP*CP*GP*CP*GP*CP*GP*CP*GP*CP*GP*C)-3'), E3 ubiquitin-protein ligase msl-2, ZINC ION
著者Zheng, S, Ye, K.
登録日2014-10-13
公開日2015-01-21
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis of X chromosome DNA recognition by the MSL2 CXC domain during Drosophila dosage compensation.
Genes Dev., 28, 2014
1BID
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E. COLI THYMIDYLATE SYNTHASE COMPLEXED WITH DUMP
分子名称: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, THYMIDYLATE SYNTHASE
著者Stout, T.J, Sage, C.R, Stroud, R.M.
登録日1997-06-27
公開日1998-07-01
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The additivity of substrate fragments in enzyme-ligand binding.
Structure, 6, 1998
1X59
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Solution structures of the WHEP-TRS domain of human histidyl-tRNA synthetase
分子名称: Histidyl-tRNA synthetase
著者Nameki, N, Sasagawa, A, Tomizawa, T, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-05-15
公開日2005-11-15
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structures of the WHEP-TRS domain of human histidyl-tRNA synthetase
To be Published
1AN5
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E. COLI THYMIDYLATE SYNTHASE IN COMPLEX WITH CB3717
分子名称: 10-PROPARGYL-5,8-DIDEAZAFOLIC ACID, PHOSPHATE ION, THYMIDYLATE SYNTHASE
著者Stout, T.J, Sage, C.R, Stroud, R.M.
登録日1997-06-26
公開日1998-07-01
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The additivity of substrate fragments in enzyme-ligand binding.
Structure, 6, 1998
4RKH
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Structure of the MSL2 CXC domain bound with a specific MRE sequence
分子名称: DNA (5'-D(*AP*TP*CP*CP*AP*TP*CP*TP*CP*GP*CP*TP*CP*AP*T)-3'), DNA (5'-D(*AP*TP*GP*AP*GP*CP*GP*AP*GP*AP*TP*GP*GP*AP*T)-3'), E3 ubiquitin-protein ligase msl-2, ...
著者Zheng, S, Ye, K.
登録日2014-10-13
公開日2015-01-21
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis of X chromosome DNA recognition by the MSL2 CXC domain during Drosophila dosage compensation.
Genes Dev., 28, 2014
1AOB
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E. COLI THYMIDYLATE SYNTHASE COMPLEXED WITH DDURD
分子名称: 2'-5'DIDEOXYURIDINE, FORMIC ACID, PHOSPHATE ION, ...
著者Stout, T.J, Sage, C.R, Stroud, R.M.
登録日1997-06-30
公開日1998-07-01
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The additivity of substrate fragments in enzyme-ligand binding.
Structure, 6, 1998
1BDU
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E. COLI THYMIDYLATE SYNTHASE COMPLEXED WITH DURD
分子名称: 2'-DEOXYURIDINE, PHOSPHATE ION, THYMIDYLATE SYNTHASE
著者Stout, T.J, Sage, C.R, Stroud, R.M.
登録日1997-06-27
公開日1998-07-01
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The additivity of substrate fragments in enzyme-ligand binding.
Structure, 6, 1998
1V9Y
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Crystal Structure of the heme PAS sensor domain of Ec DOS (ferric form)
分子名称: Heme pas sensor protein, PROTOPORPHYRIN IX CONTAINING FE
著者Kurokawa, H, Lee, D.S, Watanabe, M, Sagami, I, Mikami, B, Raman, C.S, Shimizu, T.
登録日2004-02-04
公開日2004-05-25
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.32 Å)
主引用文献A redox-controlled molecular switch revealed by the crystal structure of a bacterial heme PAS sensor.
J.Biol.Chem., 279, 2004
1B6C
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CRYSTAL STRUCTURE OF THE CYTOPLASMIC DOMAIN OF THE TYPE I TGF-BETA RECEPTOR IN COMPLEX WITH FKBP12
分子名称: FK506-BINDING PROTEIN, SULFATE ION, TGF-B SUPERFAMILY RECEPTOR TYPE I
著者Huse, M, Chen, Y.-G, Massague, J, Kuriyan, J.
登録日1999-01-13
公開日1999-06-15
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of the cytoplasmic domain of the type I TGF beta receptor in complex with FKBP12.
Cell(Cambridge,Mass.), 96, 1999
1RG9
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S-Adenosylmethionine synthetase complexed with SAM and PPNP
分子名称: (DIPHOSPHONO)AMINOPHOSPHONIC ACID, MAGNESIUM ION, POTASSIUM ION, ...
著者Komoto, J, Yamada, T, Takata, Y, Markham, G.D, Takusagawa, F.
登録日2003-11-11
公開日2004-03-02
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of the S-adenosylmethionine synthetase ternary complex: a novel catalytic mechanism of s-adenosylmethionine synthesis from ATP and MET.
Biochemistry, 43, 2004
1B3R
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RAT LIVER S-ADENOSYLHOMOCYSTEIN HYDROLASE
分子名称: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PROTEIN (S-ADENOSYLHOMOCYSTEINE HYDROLASE)
著者Hu, Y, Komoto, J, Huang, Y, Takusagawa, F, Gomi, T, Ogawa, H, Takata, Y, Fujioka, M.
登録日1998-12-14
公開日1998-12-23
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of S-adenosylhomocysteine hydrolase from rat liver.
Biochemistry, 38, 1999
1NBH
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Structure of glycine N-methyltransferase complexed with S-adenosylmethionine and acetate, GNMT:SAM:Ace
分子名称: ACETATE ION, Glycine N-methyltransferase, S-ADENOSYLMETHIONINE
著者Takata, Y, Takusagawa, F.
登録日2002-12-02
公開日2003-03-04
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Catalytic mechanism of glycine N-methyltransferase
Biochemistry, 42, 2003
1X5F
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The solution structure of the first fibronectin type III domain of human Neogenin
分子名称: Neogenin
著者Tochio, N, Sasagawa, A, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-05-15
公開日2005-11-15
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献The solution structure of the first fibronectin type III domain of human Neogenin
To be Published
1UXC
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FRUCTOSE REPRESSOR DNA-BINDING DOMAIN, NMR, MINIMIZED STRUCTURE
分子名称: FRUCTOSE REPRESSOR
著者Penin, F, Geourjon, C, Montserret, R, Bockmann, A, Lesage, A, Yang, Y, Bonod-Bidaud, C, Cortay, J.C, Negre, D, Cozzone, A.J, Deleage, G.
登録日1996-12-26
公開日1997-04-21
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Three-dimensional structure of the DNA-binding domain of the fructose repressor from Escherichia coli by 1H and 15N NMR.
J.Mol.Biol., 270, 1997
1V9Z
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Crystal Structure of the heme PAS sensor domain of Ec DOS (Ferrous Form)
分子名称: Heme pas sensor protein, PROTOPORPHYRIN IX CONTAINING FE
著者Kurokawa, H, Lee, D.S, Watanabe, M, Sagami, I, Mikami, B, Raman, C.S, Shimizu, T.
登録日2004-02-04
公開日2004-05-25
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A redox-controlled molecular switch revealed by the crystal structure of a bacterial heme PAS sensor.
J.Biol.Chem., 279, 2004
172D
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BU of 172d by Molmil
MULTIPLE BINDING MODES OF ANTICANCER DRUG ACTINOMYCIN D: X-RAY, MOLECULAR MODELING, AND SPECTROSCOPIC STUDIES OF D(GAAGCTTC)2-ACTINOMYCIN D COMPLEXES AND ITS HOST DNA
分子名称: DNA (5'-D(*GP*AP*AP*GP*CP*TP*TP*C)-3')
著者Kamitori, S, Takusagawa, F.
登録日1994-04-18
公開日1994-10-15
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Multiple Binding Modes of Anticancer Drug Actinomycin D: X-Ray, Molecular Modeling, and Spectroscopic Studies of d(GAAGCTTC)2-Actinomycin D Complexes and Its Host DNA
J.Am.Chem.Soc., 116, 1994
1X5H
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The solution structure of the third fibronectin type III domain of human Neogenin
分子名称: Neogenin
著者Tochio, N, Sasagawa, A, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-05-15
公開日2005-11-15
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献The solution structure of the third fibronectin type III domain of human Neogenin
To be Published
2QZ4
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Human paraplegin, AAA domain in complex with ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, Paraplegin
著者Karlberg, T, Lehtio, L, Arrowsmith, C.H, Berglund, H, Busam, R.D, Collins, R, Dahlgren, L.G, Edwards, A, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Herman, M.D, Johansson, I, Kallas, A, Kotenyova, T, Moche, M, Nilsson, M.E, Nordlund, P, Nyman, T, Persson, J, Sagemark, C, Sundstrom, M, Thorsell, A.G, Tresauges, L, Van Den Berg, S, Weigelt, J, Welin, M, Holmberg-Schiavone, L, Structural Genomics Consortium (SGC)
登録日2007-08-16
公開日2007-09-11
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献Crystal Structure of the ATPase Domain of the Human AAA+ Protein Paraplegin/SPG7.
Plos One, 4, 2009
1X5A
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The solution structure of the second fibronectin type III domain of mouse Ephrin type-A receptor 1
分子名称: Ephrin type-A receptor 1
著者Tochio, N, Sasagawa, A, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-05-15
公開日2005-11-15
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献The solution structure of the second fibronectin type III domain of mouse Ephrin type-A receptor 1
To be Published
1X5J
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The solution structure of the fifth fibronectin type III domain of human Neogenin
分子名称: Neogenin
著者Tochio, N, Sasagawa, A, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-05-15
公開日2005-11-15
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献The solution structure of the fifth fibronectin type III domain of human Neogenin
To be Published
1RY8
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Prostaglandin F synthase complexed with NADPH and rutin
分子名称: Aldo-keto reductase family 1 member C3, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, RUTIN
著者Komoto, J, Yamada, T, Watanabe, K, Takusagawa, F.
登録日2003-12-19
公開日2004-11-02
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献Crystal structure of human prostaglandin F synthase (AKR1C3).
Biochemistry, 43, 2004
2JCN
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The crystal structure of BAK1 - a mitochondrial apoptosis regulator
分子名称: BCL-2 HOMOLOGOUS ANTAGONIST/KILLER, SULFATE ION
著者Moche, M, Stenmark, P, Arrowsmith, C, Berglund, H, Busam, R, Collins, R, Edwards, A, Ericsson, U.B, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hallberg, B.M, Holmberg Schiavone, L, Johansson, I, Karlberg, T, Kosinska, U, Kotenyova, T, Lundgren, S, Nilsson, M.E, Nyman, T, Ogg, D, Persson, C, Sagemark, J, Sundstrom, M, Uppenberg, J, Upsten, M, Thorsell, A.G, van den Berg, S, Weigelt, J, Nordlund, P, Structural Genomics Consortium (SGC)
登録日2006-12-27
公開日2007-01-04
最終更新日2018-06-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The Crystal Structure of Bak1 - an Apoptosis Trigger in the Mitochondrial Outer Membrane
To be Published
4LTE
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Structure of Cysteine-free Human Insulin Degrading Enzyme in Complex with Macrocyclic Inhibitor
分子名称: 2,6-DIAMINO-HEXANOIC ACID AMIDE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, FUMARIC ACID, ...
著者Foda, Z.H, Seeliger, M.A, Saghatelian, A, Liu, D.R.
登録日2013-07-23
公開日2014-05-21
最終更新日2024-04-24
実験手法X-RAY DIFFRACTION (2.705 Å)
主引用文献Anti-diabetic activity of insulin-degrading enzyme inhibitors mediated by multiple hormones.
Nature, 511, 2014
4LJ5
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ClpB NBD2 from T. thermophilus in complex with ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, Chaperone protein ClpB
著者Zeymer, C, Barends, T.R.M, Werbeck, N.D, Schlichting, I, Reinstein, J.
登録日2013-07-04
公開日2014-02-12
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Elements in nucleotide sensing and hydrolysis of the AAA+ disaggregation machine ClpB: a structure-based mechanistic dissection of a molecular motor
Acta Crystallogr.,Sect.D, 70, 2014

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