2JCN

The crystal structure of BAK1 - a mitochondrial apoptosis regulator

Summary for 2JCN

Related1BXL
DescriptorBCL-2 HOMOLOGOUS ANTAGONIST/KILLER, SULFATE ION (3 entities in total)
Functional Keywordsapoptosis, mitochondrial outer membrane permeabilization, oligomerization, cytochrome c release, membrane, transmembrane
Biological sourceHOMO SAPIENS (HUMAN)
Total number of polymer chains1
Total molecular weight19420.76
Authors
Primary citation
Moche, M.,Stenmark, P.,Arrowsmith, C.,Berglund, H.,Busam, R.,Collins, R.,Edwards, A.,Ericsson, U.B.,Flodin, S.,Flores, A.,Graslund, S.,Hammarstrom, M.,Hallberg, B.M.,Holmberg Schiavone, L.,Johansson, I.,Karlberg, T.,Kosinska, U.,Kotenyova, T.,Lundgren, S.,Nilsson, M.E.,Nyman, T.,Ogg, D.,Persson, C.,Sagemark, J.,Sundstrom, M.,Uppenberg, J.,Upsten, M.,Thorsell, A.G.,Van Den Berg, S.,Weigelt, J.,Nordlund, P.
The Crystal Structure of Bak1 - an Apoptosis Trigger in the Mitochondrial Outer Membrane
To be Published,
Experimental method
X-RAY DIFFRACTION (1.8 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.248106.9%12.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report