1AN5

E. COLI THYMIDYLATE SYNTHASE IN COMPLEX WITH CB3717

Summary for 1AN5

Entry DOI	10.2210/pdb1an5/pdb
Descriptor	THYMIDYLATE SYNTHASE, PHOSPHATE ION, 10-PROPARGYL-5,8-DIDEAZAFOLIC ACID, ... (4 entities in total)
Functional Keywords	transferase (methyltransferase), substrate modules, methyltransferase
Biological source	Escherichia coli
Cellular location	Cytoplasm: P0A884
Total number of polymer chains	2
Total formula weight	62232.20
Authors	Stout, T.J.,Sage, C.R.,Stroud, R.M. (deposition date: 1997-06-26, release date: 1998-07-01, Last modification date: 2023-08-02)
Primary citation	Stout, T.J.,Sage, C.R.,Stroud, R.M. The additivity of substrate fragments in enzyme-ligand binding. Structure, 6:839-848, 1998 Cited by PubMed: 9687366 DOI: 10.1016/S0969-2126(98)00086-0 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation