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8K9I
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Structure of CUL3-RBX1-KLHL22 complex without CUL3 NA motif
分子名称: Cullin-3, E3 ubiquitin-protein ligase RBX1, N-terminally processed, ...
著者Wang, W, Ling, L, Dai, Z, Zuo, P, Yin, Y.
登録日2023-08-01
公開日2024-05-29
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献A conserved N-terminal motif of CUL3 contributes to assembly and E3 ligase activity of CRL3 KLHL22.
Nat Commun, 15, 2024
8GQ6
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BU of 8gq6 by Molmil
Cryo-EM Structure of the KBTBD2-CUL3-Rbx1 dimeric complex
分子名称: Cullin-3, E3 ubiquitin-protein ligase RBX1, Kelch repeat and BTB domain-containing protein 2, ...
著者Sun, L, Chen, Z, Hu, Y, Mao, Q.
登録日2022-08-29
公開日2023-09-06
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.96 Å)
主引用文献Dynamic molecular architecture and substrate recruitment of cullin3-RING E3 ligase CRL3 KBTBD2.
Nat.Struct.Mol.Biol., 31, 2024
6UE5
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Crystal structure of full-length human DCAF15-DDB1-deltaPBP-DDA1-RBM39 in complex with 4-(aminomethyl)-N-(3-cyano-4-methyl-1H-indol-7-yl)benzenesulfonamide
分子名称: 4-(aminomethyl)-N-(3-cyano-4-methyl-1H-indol-7-yl)benzene-1-sulfonamide, DDB1- and CUL4-associated factor 15, DET1- and DDB1-associated protein 1, ...
著者Knapp, M.S, Shu, W, Xie, L, Bussiere, D.E.
登録日2019-09-20
公開日2019-12-18
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Structural basis of indisulam-mediated RBM39 recruitment to DCAF15 E3 ligase complex.
Nat.Chem.Biol., 16, 2020
2B5L
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BU of 2b5l by Molmil
Crystal Structure of DDB1 In Complex with Simian Virus 5 V Protein
分子名称: Nonstructural protein V, ZINC ION, damage-specific DNA binding protein 1
著者Li, T, Chen, X, Garbutt, K.C, Zhou, P, Zheng, N.
登録日2005-09-28
公開日2006-02-28
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structure of DDB1 in complex with a paramyxovirus V protein: viral hijack of a propeller cluster in ubiquitin ligase.
Cell(Cambridge,Mass.), 124, 2006
8KG8
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BU of 8kg8 by Molmil
Yeast replisome in state II
分子名称: ADENOSINE-5'-DIPHOSPHATE, Cell division control protein 45, DNA (61-mer), ...
著者Dang, S, Zhai, Y, Feng, J, Yu, D, Xu, Z.
登録日2023-08-17
公開日2023-12-06
実験手法ELECTRON MICROSCOPY (4.23 Å)
主引用文献Synergism between CMG helicase and leading strand DNA polymerase at replication fork.
Nat Commun, 14, 2023
8W7S
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BU of 8w7s by Molmil
Yeast replisome in state IV
分子名称: Cell division control protein 45, DNA (71-mer), DNA polymerase alpha-binding protein, ...
著者Dang, S, Zhai, Y, Feng, J, Yu, D.
登録日2023-08-31
公開日2023-12-20
実験手法ELECTRON MICROSCOPY (7.39 Å)
主引用文献Synergism between CMG helicase and leading strand DNA polymerase at replication fork.
Nat Commun, 14, 2023
8KG6
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BU of 8kg6 by Molmil
Yeast replisome in state I
分子名称: ADENOSINE-5'-DIPHOSPHATE, Cell division control protein 45, Chromosome segregation in meiosis protein 3, ...
著者Dang, S, Zhai, Y, Feng, J, Yu, D, Xu, Z.
登録日2023-08-17
公開日2023-12-06
実験手法ELECTRON MICROSCOPY (3.07 Å)
主引用文献Synergism between CMG helicase and leading strand DNA polymerase at replication fork.
Nat Commun, 14, 2023
8KG9
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BU of 8kg9 by Molmil
Yeast replisome in state III
分子名称: ADENOSINE-5'-DIPHOSPHATE, Cell division control protein 45, DNA (61-mer), ...
著者Dang, S, Zhai, Y, Feng, J, Yu, D, Xu, Z.
登録日2023-08-17
公開日2023-12-06
実験手法ELECTRON MICROSCOPY (4.52 Å)
主引用文献Synergism between CMG helicase and leading strand DNA polymerase at replication fork.
Nat Commun, 14, 2023
8AG5
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BU of 8ag5 by Molmil
Vaccinia C16 protein bound to Ku70/Ku80
分子名称: Ku70-Xrcc6, Protein C10, X-ray repair cross-complementing protein 5
著者Rivera-Calzada, A, Arribas-Bosacoma, R, Pearl, L.H, Llorca, O.
登録日2022-07-19
公開日2022-11-09
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (3.47 Å)
主引用文献Structural basis for the inactivation of cytosolic DNA sensing by the vaccinia virus.
Nat Commun, 13, 2022
8AG4
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BU of 8ag4 by Molmil
Vaccinia C16 protein bound to Ku70/Ku80
分子名称: Protein C10, X-ray repair cross-complementing protein 5, X-ray repair cross-complementing protein 6
著者Rivera-Calzada, A, Arribas-Bosacoma, R, Pearl, L.H, Llorca, O.
登録日2022-07-19
公開日2022-11-09
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (2.46 Å)
主引用文献Structural basis for the inactivation of cytosolic DNA sensing by the vaccinia virus.
Nat Commun, 13, 2022
8W7M
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BU of 8w7m by Molmil
Yeast replisome in state V
分子名称: ADENOSINE-5'-DIPHOSPHATE, Cell division control protein 45, DNA (71-mer), ...
著者Dang, S, Zhai, Y, Feng, J, Yu, D, Xu, Z.
登録日2023-08-30
公開日2023-12-06
実験手法ELECTRON MICROSCOPY (4.12 Å)
主引用文献Synergism between CMG helicase and leading strand DNA polymerase at replication fork.
Nat Commun, 14, 2023
2B5M
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BU of 2b5m by Molmil
Crystal Structure of DDB1
分子名称: damage-specific DNA binding protein 1
著者Li, T, Chen, X, Garbutt, K.C, Zhou, P, Zheng, N.
登録日2005-09-28
公開日2006-02-28
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.92 Å)
主引用文献Structure of DDB1 in complex with a paramyxovirus V protein: viral hijack of a propeller cluster in ubiquitin ligase.
Cell(Cambridge,Mass.), 124, 2006
1MA7
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BU of 1ma7 by Molmil
Crystal structure of Cre site-specific recombinase complexed with a mutant DNA substrate, LoxP-A8/T27
分子名称: CRE RECOMBINASE, LOXP
著者Martin, S.S, Chu, V.C, Baldwin, E.P.
登録日2002-08-01
公開日2003-07-08
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Modulation of the active complex assembly and turnover rate by protein-DNA interactions in Cre-LoxP recombination
Biochemistry, 42, 2003
6FE8
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BU of 6fe8 by Molmil
Cryo-EM structure of the core Centromere Binding Factor 3 complex
分子名称: Centromere DNA-binding protein complex CBF3 subunit B, Centromere DNA-binding protein complex CBF3 subunit C, Suppressor of kinetochore protein 1
著者Zhang, W.J, Lukoynova, N, Miah, S, Vaughan, C.K.
登録日2017-12-30
公開日2018-08-01
最終更新日2019-12-11
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Insights into Centromere DNA Bending Revealed by the Cryo-EM Structure of the Core Centromere Binding Factor 3 with Ndc10.
Cell Rep, 24, 2018
1BIA
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BU of 1bia by Molmil
THE E. COLI BIOTIN HOLOENZYME SYNTHETASE(SLASH)BIO REPRESSOR CRYSTAL STRUCTURE DELINEATES THE BIOTIN AND DNA-BINDING DOMAINS
分子名称: BirA BIFUNCTIONAL PROTEIN
著者Wilson, K.P, Shewchuk, L.M, Matthews, B.W.
登録日1992-07-06
公開日1993-10-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Escherichia coli biotin holoenzyme synthetase/bio repressor crystal structure delineates the biotin- and DNA-binding domains.
Proc.Natl.Acad.Sci.USA, 89, 1992
6GSA
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BU of 6gsa by Molmil
Core Centromere Binding Factor 3 (CBF3) with monomeric Ndc10
分子名称: Centromere DNA-binding protein complex CBF3 subunit A, Centromere DNA-binding protein complex CBF3 subunit B, Centromere DNA-binding protein complex CBF3 subunit C, ...
著者Zhang, W.J, Lukoynova, N, Vaughan, C.K.
登録日2018-06-13
公開日2018-08-01
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Insights into Centromere DNA Bending Revealed by the Cryo-EM Structure of the Core Centromere Binding Factor 3 with Ndc10.
Cell Rep, 24, 2018
1BIB
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BU of 1bib by Molmil
THE E. COLI BIOTIN HOLOENZYME SYNTHETASE(SLASH)BIO REPRESSOR CRYSTAL STRUCTURE DELINEATES THE BIOTIN AND DNA-BINDING DOMAINS
分子名称: BIOTIN, BIR A
著者Wilson, K.P, Shewchuk, L.M, Matthews, B.W.
登録日1992-07-06
公開日1993-10-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Escherichia coli biotin holoenzyme synthetase/bio repressor crystal structure delineates the biotin- and DNA-binding domains.
Proc.Natl.Acad.Sci.USA, 89, 1992
3CRX
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BU of 3crx by Molmil
CRE RECOMBINASE/DNA COMPLEX INTERMEDIATE I
分子名称: CRE RECOMBINASE, DNA 35-MER
著者Gopaul, D.N, Guo, F, Vanduyne, G.D.
登録日1998-06-19
公開日1999-12-14
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of the Holliday junction intermediate in Cre-loxP site-specific recombination.
EMBO J., 17, 1998
7ONI
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BU of 7oni by Molmil
Structure of Neddylated CUL5 C-terminal region-RBX2-ARIH2*
分子名称: Cullin-5, E3 ubiquitin-protein ligase ARIH2, NEDD8, ...
著者Kostrhon, S.P, prabu, J.R, Schulman, B.A.
登録日2021-05-25
公開日2021-09-15
最終更新日2024-11-06
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献CUL5-ARIH2 E3-E3 ubiquitin ligase structure reveals cullin-specific NEDD8 activation.
Nat.Chem.Biol., 17, 2021
7MWD
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BU of 7mwd by Molmil
HUWE1 in map with focus on HECT
分子名称: E3 ubiquitin-protein ligase HUWE1
著者Hunkeler, M, Fischer, E.S.
登録日2021-05-16
公開日2021-07-28
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Solenoid architecture of HUWE1 contributes to ligase activity and substrate recognition.
Mol.Cell, 81, 2021
7MWF
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BU of 7mwf by Molmil
HUWE1 in map with focus on interface
分子名称: E3 ubiquitin-protein ligase HUWE1
著者Hunkeler, M, Fischer, E.S.
登録日2021-05-16
公開日2021-07-28
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Solenoid architecture of HUWE1 contributes to ligase activity and substrate recognition.
Mol.Cell, 81, 2021
7MWE
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BU of 7mwe by Molmil
HUWE1 in map with focus on WWE
分子名称: E3 ubiquitin-protein ligase HUWE1
著者Hunkeler, M, Fischer, E.S.
登録日2021-05-16
公開日2021-07-28
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Solenoid architecture of HUWE1 contributes to ligase activity and substrate recognition.
Mol.Cell, 81, 2021
8BJA
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BU of 8bja by Molmil
Structure of the human UBR5 Dimer.
分子名称: E3 ubiquitin-protein ligase UBR5, ZINC ION
著者Hodakova, Z, Grishkovskaya, I, Haselbach, D.
登録日2022-11-03
公開日2023-07-12
最終更新日2023-09-06
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Cryo-EM structure of the chain-elongating E3 ubiquitin ligase UBR5.
Embo J., 42, 2023
7XZZ
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BU of 7xzz by Molmil
Cryo-EM structure of the nucleosome in complex with p53
分子名称: Cellular tumor antigen p53, DNA (169-MER), Histone H2A type 1-B/E, ...
著者Nishimura, M, Nozawa, K, Takizawa, Y, Kurumizaka, H.
登録日2022-06-03
公開日2022-10-12
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (4.07 Å)
主引用文献Structural basis for p53 binding to its nucleosomal target DNA sequence.
Pnas Nexus, 1, 2022
8B5W
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BU of 8b5w by Molmil
Crystal structure of the E3 module from UBR4
分子名称: 1,2-ETHANEDIOL, ZINC ION, cDNA FLJ12511 fis, ...
著者Virdee, S, Mabbitt, P.D, Barnsby-Greer, L.
登録日2022-09-24
公開日2023-10-04
最終更新日2024-04-17
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献UBE2A and UBE2B are recruited by an atypical E3 ligase module in UBR4.
Nat.Struct.Mol.Biol., 31, 2024

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件を2024-11-06に公開中

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