8B5W

Crystal structure of the E3 module from UBR4

Summary for 8B5W

Entry DOI	10.2210/pdb8b5w/pdb
Descriptor	cDNA FLJ12511 fis, clone NT2RM2001727, highly similar to Homo sapiens ubiquitin protein ligase E3 component n-recognin 4 (UBR4), mRNA, ZINC ION, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywords	ubiquitin, e3 ligase, zinc finger, ligase
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	51945.46
Authors	Virdee, S.,Mabbitt, P.D.,Barnsby-Greer, L. (deposition date: 2022-09-24, release date: 2023-10-04, Last modification date: 2024-04-17)
Primary citation	Barnsby-Greer, L.,Mabbitt, P.D.,Dery, M.A.,Squair, D.R.,Wood, N.T.,Lamoliatte, F.,Lange, S.M.,Virdee, S. UBE2A and UBE2B are recruited by an atypical E3 ligase module in UBR4. Nat.Struct.Mol.Biol., 31:351-363, 2024 Cited by PubMed: 38182926 DOI: 10.1038/s41594-023-01192-4 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation