6EBY
 
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3VL4
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6IME
 | | Rv2361c complex with substrate analogues | | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 3-methylbut-3-enylsulfanyl(phosphonooxy)phosphinic acid, CARBONATE ION, ... | | 著者 | Ko, T.-P, Guo, R.-T, Chen, C.-C, Liu, W. | | 登録日 | 2018-10-22 | | 公開日 | 2019-09-04 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Substrate-analogue complex structure of Mycobacterium tuberculosis decaprenyl diphosphate synthase.
Acta Crystallogr.,Sect.F, 75, 2019
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3VL7
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6J5G
 | | Complex structure of MAb 4.2-scFv with tick-borne encephalitis virus envelope protein | | 分子名称: | Envelope protein E, antibody heavy chain, antibody light chain | | 著者 | Yang, X, Qi, J, Peng, R, Dai, L, Gould, E.A, Tien, P, Gao, G.F. | | 登録日 | 2019-01-10 | | 公開日 | 2019-02-06 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.291 Å) | | 主引用文献 | Molecular Basis of a Protective/Neutralizing Monoclonal Antibody Targeting Envelope Proteins of both Tick-Borne Encephalitis Virus and Louping Ill Virus.
J. Virol., 93, 2019
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4D5L
 | | Cryo-EM structures of ribosomal 80S complexes with termination factors and cricket paralysis virus IRES reveal the IRES in the translocated state | | 分子名称: | 18S RRNA 2, 40S RIBOSOMAL PROTEIN ES1, 40S RIBOSOMAL PROTEIN ES10, ... | | 著者 | Muhs, M, Hilal, T, Mielke, T, Skabkin, M.A, Sanbonmatsu, K.Y, Pestova, T.V, Spahn, C.M.T. | | 登録日 | 2014-11-05 | | 公開日 | 2015-02-04 | | 最終更新日 | 2017-08-23 | | 実験手法 | ELECTRON MICROSCOPY (9 Å) | | 主引用文献 | Cryo-Em of Ribosomal 80S Complexes with Termination Factors Reveals the Translocated Cricket Paralysis Virus Ires.
Mol.Cell, 57, 2015
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4D5Y
 | | Cryo-EM structures of ribosomal 80S complexes with termination factors and cricket paralysis virus IRES reveal the IRES in the translocated state | | 分子名称: | 28S Ribosomal RNA, 5.8S Ribosomal RNA, 5S Ribosomal RNA, ... | | 著者 | Muhs, M, Hilal, T, Mielke, T, Skabkin, M.A, Sanbonmatsu, K.Y, Pestova, T.V, Spahn, C.M.T. | | 登録日 | 2014-11-07 | | 公開日 | 2015-03-04 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (9 Å) | | 主引用文献 | Cryo-Em Structures of Ribosomal 80S Complexes with Termination Factors and Cricket Paralysis Virus Ires Reveal the Ires in the Translocated State
Mol.Cell, 57, 2015
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6H05
 | | Cryo-electron microscopic structure of the dihydrolipoamide succinyltransferase (E2) component of the human alpha-ketoglutarate (2-oxoglutarate) dehydrogenase complex [residues 218-453] | | 分子名称: | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial | | 著者 | Nagy, B, Zambo, Z, Hubert, A, Polak, M, Nemeria, N.S, Novacek, J, Jordan, F, Adam-Vizi, V, Ambrus, A. | | 登録日 | 2018-07-06 | | 公開日 | 2020-01-22 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Structure of the dihydrolipoamide succinyltransferase (E2) component of the human alpha-ketoglutarate dehydrogenase complex (hKGDHc) revealed by cryo-EM and cross-linking mass spectrometry: Implications for the overall hKGDHc structure.
Biochim Biophys Acta Gen Subj, 1865, 2021
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5GG7
 | | Crystal structure of Mycobacterium smegmatis MutT1 in complex with 8-oxo-dGTP, 8-oxo-dGMP and pyrophosphate (I) | | 分子名称: | 8-OXO-2'-DEOXY-GUANOSINE-5'-MONOPHOSPHATE, 8-OXO-2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, Hydrolase, ... | | 著者 | Arif, S.M, Patil, A.G, Varshney, U, Vijayan, M. | | 登録日 | 2016-06-15 | | 公開日 | 2017-04-19 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Biochemical and structural studies of Mycobacterium smegmatis MutT1, a sanitization enzyme with unusual modes of association
Acta Crystallogr D Struct Biol, 73, 2017
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5GGC
 | | Crystal structure of Mycobacterium smegmatis MutT1 in complex with phosphate and magnesium ions (excess magnesium, I) | | 分子名称: | Hydrolase, NUDIX family protein, MAGNESIUM ION, ... | | 著者 | Arif, S.M, Patil, A.G, Varshney, U, Vijayan, M. | | 登録日 | 2016-06-15 | | 公開日 | 2017-04-19 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Biochemical and structural studies of Mycobacterium smegmatis MutT1, a sanitization enzyme with unusual modes of association
Acta Crystallogr D Struct Biol, 73, 2017
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1AFQ
 | | CRYSTAL STRUCTURE OF BOVINE GAMMA-CHYMOTRYPSIN COMPLEXED WITH A SYNTHETIC INHIBITOR | | 分子名称: | BOVINE GAMMA-CHYMOTRYPSIN, D-leucyl-N-(4-fluorobenzyl)-L-phenylalaninamide, SULFATE ION | | 著者 | Sugio, S, Kashima, A, Inoue, Y, Maeda, I, Nose, T, Shimohigashi, Y. | | 登録日 | 1997-03-12 | | 公開日 | 1997-09-17 | | 最終更新日 | 2023-08-02 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | X-ray crystal structure of a dipeptide-chymotrypsin complex in an inhibitory interaction.
Eur.J.Biochem., 255, 1998
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3ZD2
 | | THE STRUCTURE OF THE TWO N-TERMINAL DOMAINS OF COMPLEMENT FACTOR H RELATED PROTEIN 1 SHOWS FORMATION OF A NOVEL DIMERISATION INTERFACE | | 分子名称: | 1,2-ETHANEDIOL, COMPLEMENT FACTOR H-RELATED PROTEIN 1 | | 著者 | Caesar, J.J.E, Goicoechea de Jorge, E, Pickering, M.C, Lea, S.M. | | 登録日 | 2012-11-23 | | 公開日 | 2013-03-13 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | Dimerization of Complement Factor H-Related Proteins Modulates Complement Activation in Vivo.
Proc.Natl.Acad.Sci.USA, 110, 2013
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3ZGX
 | | Crystal structure of the kleisin-N SMC interface in prokaryotic condensin | | 分子名称: | CHROMOSOME PARTITION PROTEIN SMC, SEGREGATION AND CONDENSATION PROTEIN A | | 著者 | Burmann, F, Shin, H, Basquin, J, Soh, Y, Gimenez, V, Kim, Y, Oh, B, Gruber, S. | | 登録日 | 2012-12-19 | | 公開日 | 2013-01-30 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | An Asymmetric Smc-Kleisin Bridge in Prokaryotic Condensin.
Nat.Struct.Mol.Biol., 20, 2013
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4IM3
 | | Structure of Tank-Binding Kinase 1 | | 分子名称: | CHLORIDE ION, MERCURY (II) ION, N-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide, ... | | 著者 | Tu, D, Eck, M.J. | | 登録日 | 2013-01-01 | | 公開日 | 2013-03-06 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.342 Å) | | 主引用文献 | Structure and ubiquitination-dependent activation of TANK-binding kinase 1.
Cell Rep, 3, 2013
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4P4T
 | | GDP-bound stalkless-MxA | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Interferon-induced GTP-binding protein Mx1, SULFATE ION | | 著者 | Rennie, M.L, McKelvie, S.A, Bulloch, E.M, Kingston, R.L. | | 登録日 | 2014-03-13 | | 公開日 | 2014-10-22 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Transient Dimerization of Human MxA Promotes GTP Hydrolysis, Resulting in a Mechanical Power Stroke.
Structure, 22, 2014
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4IM2
 | | Structure of Tank-Binding Kinase 1 | | 分子名称: | CHLORIDE ION, N-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide, Serine/threonine-protein kinase TBK1 | | 著者 | Tu, D, Eck, M.J. | | 登録日 | 2013-01-01 | | 公開日 | 2013-03-06 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.5001 Å) | | 主引用文献 | Structure and ubiquitination-dependent activation of TANK-binding kinase 1.
Cell Rep, 3, 2013
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4IM0
 | | Structure of Tank-Binding Kinase 1 | | 分子名称: | N-{3-[(5-cyclopropyl-2-{[3-(morpholin-4-ylmethyl)phenyl]amino}pyrimidin-4-yl)amino]propyl}cyclobutanecarboxamide, Serine/threonine-protein kinase TBK1 | | 著者 | Tu, D, Eck, M.J. | | 登録日 | 2013-01-01 | | 公開日 | 2013-03-06 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.4001 Å) | | 主引用文献 | Structure and ubiquitination-dependent activation of TANK-binding kinase 1.
Cell Rep, 3, 2013
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4A2Q
 | | Structure of duck RIG-I tandem CARDs and helicase domain | | 分子名称: | RETINOIC ACID INDUCIBLE PROTEIN I | | 著者 | Kowalinski, E, Lunardi, T, McCarthy, A.A, Cusack, S. | | 登録日 | 2011-09-28 | | 公開日 | 2011-10-19 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Structural Basis for the Activation of Innate Immune Pattern Recognition Receptor Rig-I by Viral RNA.
Cell(Cambridge,Mass.), 147, 2011
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8QCD
 | | STRUCTURE OF PROTEIN KINASE CK2 CATALYTIC SUBUNIT (ISOFORM CK2ALPHA'; CSNK2A2 GENE PRODUCT) IN COMPLEX WITH THE INHIBITOR 4,5,6,7-TETRABROMOBENZOTRIAZOLE | | 分子名称: | 1,2-ETHANEDIOL, 4,5,6,7-TETRABROMOBENZOTRIAZOLE, Casein kinase II subunit alpha' | | 著者 | Werner, C, Niefind, K. | | 登録日 | 2023-08-25 | | 公開日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (1.03 Å) | | 主引用文献 | Discovery and Exploration of Protein Kinase CK2 Binding Sites Using CK2alpha Cys336Ser as an Exquisite Crystallographic Tool
Kinases Phosphatases, 2023
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8QCG
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8Q77
 | | STRUCTURE OF PROTEIN KINASE CK2 CATALYTIC SUBUNIT (ISOFORM CK2ALPHA'; CSNK2A2 GENE PRODUCT) IN COMPLEX WITH THE BISUBSTRATE INHIBITOR ARC-780 | | 分子名称: | (2~{S})-2-[[(2~{S})-2-[[(2~{S})-2-[12-[[4-[[5-(4-carboxyphenyl)-1,3-thiazol-2-yl]amino]-4-oxidanylidene-butanoyl]-(2-hydroxy-2-oxoethyl)amino]dodecanoylamino]-4-oxidanyl-4-oxidanylidene-butanoyl]amino]-4-oxidanyl-4-oxidanylidene-butanoyl]amino]butanedioic acid, 1,2-ETHANEDIOL, CHLORIDE ION, ... | | 著者 | Werner, C, Lindenblatt, D, Niefind, K. | | 登録日 | 2023-08-15 | | 公開日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (1.255 Å) | | 主引用文献 | Discovery and Exploration of Protein Kinase CK2 Binding Sites Using CK2alpha Cys336Ser as an Exquisite Crystallographic Tool
Kinases Phosphatases, 2023
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8QF1
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8QBU
 | | STRUCTURE OF PROTEIN KINASE CK2 CATALYTIC SUBUNIT (ISOFORM CK2ALPHA'; CSNK2A2 GENE PRODUCT) IN COMPLEX WITH THE INHIBITOR CX-4945 AND THE ALPHA-D-POCKET LIGAND 3,4-DICHLORO PHENETHYLAMINE (DPA) | | 分子名称: | 1,2-ETHANEDIOL, 2-(3,4-dichlorophenyl)ethanamine, 5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid, ... | | 著者 | Werner, C, Niefind, K. | | 登録日 | 2023-08-25 | | 公開日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (1.09 Å) | | 主引用文献 | Discovery and Exploration of Protein Kinase CK2 Binding Sites Using CK2alpha Cys336Ser as an Exquisite Crystallographic Tool
Kinases Phosphatases, 2023
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3K6G
 | | Crystal structure of Rap1 and TRF2 complex | | 分子名称: | Telomeric repeat-binding factor 2, Telomeric repeat-binding factor 2-interacting protein 1 | | 著者 | Chen, Y, Rai, R, Yang, Y.T, Zheng, H, Chang, S, Lei, M. | | 登録日 | 2009-10-08 | | 公開日 | 2010-10-13 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | A conserved motif within RAP1 has diversified roles in telomere protection and regulation in different organisms.
Nat.Struct.Mol.Biol., 18, 2011
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4A5W
 | | Crystal structure of C5b6 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, COMPLEMENT C5, ... | | 著者 | Hadders, M.A, Bubeck, D, Forneris, F, Pangburn, M, Llorca, O, Lea, S.M, Gros, P. | | 登録日 | 2011-10-28 | | 公開日 | 2012-03-14 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Assembly and Regulation of the Membrane Attack Complex Based on Structures of C5B6 and Sc5B9.
Cell Rep., 1, 2012
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