6H05

Cryo-electron microscopic structure of the dihydrolipoamide succinyltransferase (E2) component of the human alpha-ketoglutarate (2-oxoglutarate) dehydrogenase complex [residues 218-453]

Summary for 6H05

Entry DOI	10.2210/pdb6h05/pdb
EMDB information	0108
Descriptor	Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial (1 entity in total)
Functional Keywords	alpha-ketoglutarate dehydrogenase complex; 2-oxoglutarate dehydrogenase complex; dihydrolipoamide succinyltransferase; e2 component, transferase
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	45543.00
Authors	Nagy, B.,Zambo, Z.,Hubert, A.,Polak, M.,Nemeria, N.S.,Novacek, J.,Jordan, F.,Adam-Vizi, V.,Ambrus, A. (deposition date: 2018-07-06, release date: 2020-01-22, Last modification date: 2021-04-07)
Primary citation	Nagy, B.,Polak, M.,Ozohanics, O.,Zambo, Z.,Szabo, E.,Hubert, A.,Jordan, F.,Novacek, J.,Adam-Vizi, V.,Ambrus, A. Structure of the dihydrolipoamide succinyltransferase (E2) component of the human alpha-ketoglutarate dehydrogenase complex (hKGDHc) revealed by cryo-EM and cross-linking mass spectrometry: Implications for the overall hKGDHc structure. Biochim Biophys Acta Gen Subj, 1865:129889-129889, 2021 Cited by PubMed: 33684457 DOI: 10.1016/j.bbagen.2021.129889 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.9 Å)

Structure validation