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2BCQ
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DNA polymerase lambda in complex with a DNA duplex containing an unpaired Dtmp
分子名称: 1,2-ETHANEDIOL, 5'-D(*CP*AP*GP*TP*AP*CP*G)-3', 5'-D(*CP*GP*GP*CP*CP*GP*TP*TP*AP*CP*TP*G)-3', ...
著者Garcia-Diaz, M, Bebenek, K, Krahn, J.M, Pedersen, L.C, Kunkel, T.A.
登録日2005-10-19
公開日2006-03-07
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structural analysis of strand misalignment during DNA synthesis by a human DNA polymerase
Cell(Cambridge,Mass.), 124, 2006
4YO7
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Crystal Structure of an ABC transporter solute binding protein (IPR025997) from Bacillus halodurans C-125 (BH2323, TARGET EFI-511484) with bound myo-inositol
分子名称: 1,2,3,4,5,6-HEXAHYDROXY-CYCLOHEXANE, CHLORIDE ION, MAGNESIUM ION, ...
著者Yadava, U, Vetting, M.W, Al Obaidi, N.F, Toro, R, Morisco, L.L, Benach, J, Koss, J, Wasserman, S.R, Attonito, J.D, Scott Glenn, A, Chamala, S, Chowdhury, S, Lafleur, J, Love, J, Seidel, R.D, Whalen, K.L, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI)
登録日2015-03-11
公開日2015-03-25
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal Structure of an ABC transporter solute binding protein (IPR025997) from Bacillus halodurans C-125 (BH2323, TARGET EFI-511484) with bound myo-inositol
To be published
4YOQ
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Crystal Structure of MutY bound to its anti-substrate
分子名称: A/G-specific adenine glycosylase, DNA (5'-D(*AP*AP*GP*AP*CP*(8OG)P*TP*GP*GP*AP*C)-3'), DNA (5'-D(*T*GP*TP*CP*CP*AP*CP*GP*TP*CP*T)-3'), ...
著者Wang, L, Lee, S, Verdine, G.L.
登録日2015-03-11
公開日2015-05-27
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Structural Basis for Avoidance of Promutagenic DNA Repair by MutY Adenine DNA Glycosylase.
J.Biol.Chem., 290, 2015
4YCX
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Binary complex of human DNA Polymerase Mu with 2-nt gapped DNA substrate
分子名称: DNA (5'-D(*CP*GP*GP*CP*AP*AP*TP*AP*CP*G)-3'), DNA (5'-D(*CP*GP*TP*A)-3'), DNA (5'-D(P*GP*CP*CP*G)-3'), ...
著者Moon, A.F, Gosavi, R.A, Kunkel, T.A, Pedersen, L.C, Bebenek, K.
登録日2015-02-20
公開日2015-08-05
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Creative template-dependent synthesis by human polymerase mu.
Proc.Natl.Acad.Sci.USA, 112, 2015
4YW9
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Structure of rat cytosolic pepck in complex with 3-mercaptopicolinic acid and GTP
分子名称: 3-sulfanylpyridine-2-carboxylic acid, GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, ...
著者Balan, M.D, Johnson, T.A, Mcleod, M.J, Lotosky, W.R, Holyoak, T.
登録日2015-03-20
公開日2015-09-23
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Inhibition and Allosteric Regulation of Monomeric Phosphoenolpyruvate Carboxykinase by 3-Mercaptopicolinic Acid.
Biochemistry, 54, 2015
3PML
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BU of 3pml by Molmil
crystal structure of a polymerase lambda variant with a dGTP analog opposite a templating T
分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]guanosine, 5'-D(*CP*AP*GP*TP*AP*C)-3', 5'-D(*CP*GP*GP*CP*TP*GP*TP*AP*CP*TP*G)-3', ...
著者Bebenek, K, Pedersen, L.C, Kunkel, T.A.
登録日2010-11-17
公開日2011-01-26
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Replication infidelity via a mismatch with Watson-Crick geometry.
Proc.Natl.Acad.Sci.USA, 108, 2011
4YVD
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BU of 4yvd by Molmil
Crytsal structure of human Pleiotropic Regulator 1 (PRL1)
分子名称: CHLORIDE ION, Pleiotropic regulator 1, SODIUM ION, ...
著者Dong, A, Zeng, H, Xu, C, Tempel, W, Li, Y, He, H, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Brown, P.J, Min, J, Wu, H, Structural Genomics Consortium (SGC)
登録日2015-03-19
公開日2015-04-15
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crytsal structure of human Pleiotropic Regulator 1 (PRL1).
to be published
6N91
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BU of 6n91 by Molmil
Crystal Structure of Adenosine Deaminase from Vibrio cholerae Complexed with Pentostatin (Deoxycoformycin)
分子名称: 1,2-ETHANEDIOL, 2'-DEOXYCOFORMYCIN, 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, ...
著者Maltseva, N, Kim, Y, Endres, M, Welk, L, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2018-11-30
公開日2018-12-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Crystal Structure of Adenosine Deaminase from Vibrio cholerae Complexed with Pentostatin (Deoxycoformycin) (CASP target)
To Be Published
4YPH
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Crystal Structure of MutY bound to its anti-substrate with the disulfide cross-linker reduced
分子名称: A/G-specific adenine glycosylase, DNA (5'-D(*AP*AP*GP*AP*CP*(8OG)P*TP*GP*GP*AP*C)-3'), DNA (5'-D(TP*GP*TP*CP*CP*AP*CP*GP*TP*CP*T)-3'), ...
著者Wang, L, Lee, S, Verdine, G.L.
登録日2015-03-12
公開日2015-05-27
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献Structural Basis for Avoidance of Promutagenic DNA Repair by MutY Adenine DNA Glycosylase.
J.Biol.Chem., 290, 2015
4YCM
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BU of 4ycm by Molmil
Crystal structure of the calcium pump with bound marine macrolide BLS
分子名称: (4S,5E,8S,9E,11S,13E,15E,18R)-8-methoxy-9,11-dimethyl-18-[(1Z,4E)-2-methylhexa-1,4-dien-1-yl]-2-oxooxacyclooctadeca-5,9,13,15-tetraen-4-yl 3-O-methyl-beta-D-glucopyranoside, PHOSPHATIDYLETHANOLAMINE, SODIUM ION, ...
著者Morita, M, Ogawa, H, Ohno, O, Yamori, T, Suenaga, K, Toyoshima, C.
登録日2015-02-20
公開日2016-01-13
最終更新日2020-02-05
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Biselyngbyasides, cytotoxic marine macrolides, are novel and potent inhibitors of the Ca(2+) pumps with a unique mode of binding
Febs Lett., 589, 2015
6N9H
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BU of 6n9h by Molmil
De novo designed homo-trimeric amantadine-binding protein
分子名称: (3S,5S,7S)-tricyclo[3.3.1.1~3,7~]decan-1-amine, SODIUM ION, amantadine-binding protein
著者Park, J, Baker, D.
登録日2018-12-03
公開日2019-12-18
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.039 Å)
主引用文献De novo design of a homo-trimeric amantadine-binding protein.
Elife, 8, 2019
4YTB
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BU of 4ytb by Molmil
Crystal structure of Porphyromonas gingivalis peptidylarginine deiminase (PPAD) in complex with dipeptide Asp-Gln.
分子名称: ASPARTIC ACID, AZIDE ION, CHLORIDE ION, ...
著者Goulas, T, Mizgalska, D, Garcia-Ferrer, I, Kantyka, T, Guevara, T, Szmigielski, B, Sroka, A, Millan, C, Uson, I, Veillard, F, Potempa, B, Mydel, P, Sola, M, Potempa, J, Gomis-Ruth, F.X.
登録日2015-03-17
公開日2015-07-01
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structure and mechanism of a bacterial host-protein citrullinating virulence factor, Porphyromonas gingivalis peptidylarginine deiminase.
Sci Rep, 5, 2015
2BCR
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BU of 2bcr by Molmil
DNA polymerase lambda in complex with a DNA duplex containing an unpaired Damp
分子名称: 1,2-ETHANEDIOL, 5'-D(*CP*AP*GP*TP*AP*CP*G)-3', 5'-D(*CP*GP*GP*CP*CP*GP*AP*TP*AP*CP*TP*G)-3', ...
著者Garcia-Diaz, M, Bebenek, K, Krahn, J.M, Pedersen, L.C, Kunkel, T.A.
登録日2005-10-19
公開日2006-03-07
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural analysis of strand misalignment during DNA synthesis by a human DNA polymerase
Cell(Cambridge,Mass.), 124, 2006
4YTG
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BU of 4ytg by Molmil
Crystal structure of Porphyromonas gingivalis peptidylarginine deiminase (PPAD) mutant C351A in complex with dipeptide Met-Arg.
分子名称: ARGININE, AZIDE ION, CHLORIDE ION, ...
著者Goulas, T, Mizgalska, D, Garcia-Ferrer, I, Kantyka, T, Guevara, T, Szmigielski, B, Sroka, A, Millan, C, Uson, I, Veillard, F, Potempa, B, Mydel, P, Sola, M, Potempa, J, Gomis-Ruth, F.X.
登録日2015-03-17
公開日2015-07-01
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure and mechanism of a bacterial host-protein citrullinating virulence factor, Porphyromonas gingivalis peptidylarginine deiminase.
Sci Rep, 5, 2015
4YXL
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BU of 4yxl by Molmil
Crystal structure of Syrian hamster prion protein complexed with POM1 FAB
分子名称: Major prion protein, POM1 FAB HEAVY CHAIN, POM1 FAB LIGHT CHAIN, ...
著者Baral, P.K, Swayampakula, M, James, M.N.G.
登録日2015-03-23
公開日2015-09-23
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.604 Å)
主引用文献X-ray structural and molecular dynamical studies of the globular domains of cow, deer, elk and Syrian hamster prion proteins.
J.Struct.Biol., 192, 2015
4YXW
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BU of 4yxw by Molmil
Bovine heart mitochondrial F1-ATPase inhibited by AMP-PNP and ADP in the presence of thiophosphate.
分子名称: ATP synthase subunit alpha, mitochondrial, ATP synthase subunit beta, ...
著者Bason, J.V, Montgomery, M.G, Leslie, A.G.W, Walker, J.E.
登録日2015-03-23
公開日2015-05-06
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献How release of phosphate from mammalian F1-ATPase generates a rotary substep.
Proc.Natl.Acad.Sci.USA, 112, 2015
4Z0O
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BU of 4z0o by Molmil
CW-type zinc finger of ZCWPW2 with F78D mutation
分子名称: SODIUM ION, UNKNOWN ATOM OR ION, ZINC ION, ...
著者Liu, Y, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
登録日2015-03-26
公開日2015-04-08
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献CW-type zinc finger of ZCWPW2 with F78D mutation
To be Published
4YZU
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BU of 4yzu by Molmil
Rapid development of two Factor IXa inhibitors from Hit to Lead
分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, CHLORIDE ION, Coagulation factor IX, ...
著者Hruza, A, Reichert, P.
登録日2015-03-25
公開日2015-05-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.41 Å)
主引用文献Rapid development of two factor IXa inhibitors from hit to lead.
Bioorg.Med.Chem.Lett., 25, 2015
2GIG
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BU of 2gig by Molmil
Alteration of sequence specificity of the type II restriction endonuclease HINCII through an indirect readout mechanism
分子名称: 5'-D(*GP*CP*CP*GP*GP*TP*CP*GP*AP*CP*CP*GP*GP*C)-3', SODIUM ION, Type II restriction enzyme HincII
著者Horton, N.C, Joshi, H.K, Etzkorn, C, Chatwell, L, Bitinaite, J.
登録日2006-03-28
公開日2006-07-18
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Alteration of Sequence Specificity of the Type II Restriction Endonuclease HincII through an Indirect Readout Mechanism.
J.Biol.Chem., 281, 2006
4Z3U
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BU of 4z3u by Molmil
PRV nuclear egress complex
分子名称: CHLORIDE ION, SODIUM ION, UL31, ...
著者Bigalke, J.M, Heldwein, E.E.
登録日2015-03-31
公開日2015-11-11
最終更新日2019-12-11
実験手法X-RAY DIFFRACTION (2.706 Å)
主引用文献Structural basis of membrane budding by the nuclear egress complex of herpesviruses.
Embo J., 34, 2015
2GU5
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BU of 2gu5 by Molmil
E. coli methionine aminopeptidase in complex with NleP, 1: 1, di-metalated
分子名称: (1-AMINO-PENTYL)-PHOSPHONIC ACID, MANGANESE (II) ION, Methionine aminopeptidase, ...
著者Ye, Q.Z.
登録日2006-04-28
公開日2006-07-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural basis of catalysis by monometalated methionine aminopeptidase.
Proc.Natl.Acad.Sci.Usa, 103, 2006
3Q94
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BU of 3q94 by Molmil
The crystal structure of fructose 1,6-bisphosphate aldolase from Bacillus anthracis str. 'Ames Ancestor'
分子名称: 1,3-DIHYDROXYACETONEPHOSPHATE, ACETATE ION, Fructose-bisphosphate aldolase, ...
著者Tan, K, Zhou, M, Kwon, K, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2011-01-07
公開日2011-01-26
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.301 Å)
主引用文献The crystal structure of fructose 1,6-bisphosphate aldolase from Bacillus anthracis str. 'Ames Ancestor'.
To be Published
2HZY
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BU of 2hzy by Molmil
Mouse fumarylacetoacetate hydrolase complexes with a transition-state mimic of the complete substrate
分子名称: 4-(2-CARBOXYETHYL)(HYDROXY)PHOSPHORYL]-3-OXOBUTANOIC ACID, CALCIUM ION, Fumarylacetoacetase, ...
著者Hurley, T.D, Timm, D.E.
登録日2006-08-09
公開日2006-08-22
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Slow-onset inhibition of fumarylacetoacetate hydrolase by phosphinate mimics of the tetrahedral intermediate: kinetics, crystal structure and pharmacokinetics.
Biochem.J., 402, 2007
6NXQ
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Crystal structure of Arabidopsis thaliana cytosolic triosephosphate isomerase C13A mutant
分子名称: SODIUM ION, Triosephosphate isomerase, cytosolic
著者Jimenez-Sandoval, P, Diaz-Quezada, C, Torres-Larios, A, Brieba, L.G.
登録日2019-02-09
公開日2020-02-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Structural basis for the modulation of plant cytosolic triosephosphate isomerase activity by mimicry of redox-based modifications.
Plant J., 99, 2019
6NVU
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Crystal structure of TLA-1 extended spectrum Beta-lactamase in complex with Clavulanic Acid
分子名称: (2R,3Z,5R)-3-(2-HYDROXYETHYLIDENE)-7-OXO-4-OXA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLIC ACID, 2,5-bis(2-hydroxyethyl)-1,3-oxazole-4-carboxylic acid, ACETATE ION, ...
著者Rudino-Pinera, E, Cifuentes-Castro, V.H, Rodriguez-Almazan, C.
登録日2019-02-05
公開日2019-12-11
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The crystal structure of ESBL TLA-1 in complex with clavulanic acid reveals a second acylation site.
Biochem.Biophys.Res.Commun., 522, 2020

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