4YPH
Crystal Structure of MutY bound to its anti-substrate with the disulfide cross-linker reduced
Summary for 4YPH
Entry DOI | 10.2210/pdb4yph/pdb |
Related | 4YOQ 4YPR |
Descriptor | A/G-specific adenine glycosylase, DNA (5'-D(*AP*AP*GP*AP*CP*(8OG)P*TP*GP*GP*AP*C)-3'), DNA (5'-D(TP*GP*TP*CP*CP*AP*CP*GP*TP*CP*T)-3'), ... (6 entities in total) |
Functional Keywords | 8-oxoguanine, base-excision repair, anti-substrate, hydrolase-dna complex, hydrolase/dna |
Biological source | Geobacillus stearothermophilus More |
Total number of polymer chains | 3 |
Total formula weight | 49196.96 |
Authors | Wang, L.,Lee, S.,Verdine, G.L. (deposition date: 2015-03-12, release date: 2015-05-27, Last modification date: 2023-09-27) |
Primary citation | Wang, L.,Lee, S.J.,Verdine, G.L. Structural Basis for Avoidance of Promutagenic DNA Repair by MutY Adenine DNA Glycosylase. J.Biol.Chem., 290:17096-17105, 2015 Cited by PubMed: 25995449DOI: 10.1074/jbc.M115.657866 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.32 Å) |
Structure validation
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