4YPH
Crystal Structure of MutY bound to its anti-substrate with the disulfide cross-linker reduced
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | A/G-specific adenine glycosylase | polymer | 369 | 42098.9 | 1 | UniProt (P83847) Pfam (PF00730) Pfam (PF00633) Pfam (PF10576) Pfam (PF14815) In PDB | Geobacillus stearothermophilus | |
2 | B | DNA (5'-D(*AP*AP*GP*AP*CP*(8OG)P*TP*GP*GP*AP*C)-3') | polymer | 11 | 3423.2 | 1 | synthetic construct | ||
3 | C | DNA (5'-D(TP*GP*TP*CP*CP*AP*CP*GP*TP*CP*T)-3') | polymer | 11 | 3300.2 | 1 | synthetic construct | ||
4 | A | IRON/SULFUR CLUSTER | non-polymer | 351.6 | 1 | Chemie (SF4) | |||
5 | A | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
6 | water | water | 18.0 | 60 | Chemie (HOH) |
Sequence modifications
A: 1 - 366 (UniProt: P83847)
PDB | External Database | Details |
---|---|---|
Gly -2 | - | expression tag |
Ser -1 | - | expression tag |
His 0 | - | expression tag |
Asp 144 | Asn 144 | engineered mutation |
Cys 164 | Pro 164 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 48822.3 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 374.6 | |
All* | Total formula weight | 49197.0 |