2GIG

Alteration of sequence specificity of the type II restriction endonuclease HINCII through an indirect readout mechanism

Summary for 2GIG

• Entry DOI: 10.2210/pdb2gig/pdb
• Related: 1HXU 1KC6 1TW8 1TX3 1XHV 2AUD 2GIE 2GIH 2GII 2GIJ
• Descriptor: 5'-D(*GP*CP*CP*GP*GP*TP*CP*GP*AP*CP*CP*GP*GP*C)-3', Type II restriction enzyme HincII, SODIUM ION, ... (4 entities in total)
• Functional Keywords: protein dna complex, indirect readout, dna intercalation, endonuclease, hydrolase-dna complex, hydrolase/dna
• Biological source: Haemophilus influenzae
• Total number of polymer chains: 4
• Total formula weight: 68289.73

Authors

Horton, N.C.,Joshi, H.K.,Etzkorn, C.,Chatwell, L.,Bitinaite, J. (deposition date: 2006-03-28, release date: 2006-07-18, Last modification date: 2023-08-30)

• Primary citation: Joshi, H.K.,Etzkorn, C.,Chatwell, L.,Bitinaite, J.,Horton, N.C.; Alteration of Sequence Specificity of the Type II Restriction Endonuclease HincII through an Indirect Readout Mechanism.; J.Biol.Chem., 281:23852-23869, 2006; PubMed: 16675462; DOI: 10.1074/jbc.M512339200

Experimental method

X-RAY DIFFRACTION (1.83 Å)