2GIG
Alteration of sequence specificity of the type II restriction endonuclease HINCII through an indirect readout mechanism
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0004518 | molecular_function | nuclease activity |
| A | 0004519 | molecular_function | endonuclease activity |
| A | 0009036 | molecular_function | type II site-specific deoxyribonuclease activity |
| A | 0009307 | biological_process | DNA restriction-modification system |
| A | 0016787 | molecular_function | hydrolase activity |
| B | 0003677 | molecular_function | DNA binding |
| B | 0004518 | molecular_function | nuclease activity |
| B | 0004519 | molecular_function | endonuclease activity |
| B | 0009036 | molecular_function | type II site-specific deoxyribonuclease activity |
| B | 0009307 | biological_process | DNA restriction-modification system |
| B | 0016787 | molecular_function | hydrolase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE NA A 501 |
| Chain | Residue |
| A | ASP114 |
| A | ASP127 |
| A | VAL128 |
| A | HOH568 |
| A | HOH605 |
| F | DG8 |
| F | DA9 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA A 502 |
| Chain | Residue |
| A | HOH571 |
| F | DG8 |
| F | HOH21 |
| A | ASP127 |
| A | ILE142 |
