7ZLH
 
 | | Cryo-EM structure of C-mannosyltransferase CeDPY19, in apo state, bound to CMT2-Fab and anti-Fab nanobody | | 分子名称: | Anti-Fab nanobody, C-mannosyltransferase dpy-19, CMT2-Fab heavy chain, ... | | 著者 | Bloch, J.S, Mukherjee, S, Irobalieva, R, Kossiakoff, A.A, Goddard-Borger, E.D, Locher, K.P. | | 登録日 | 2022-04-15 | | 公開日 | 2023-01-11 | | 最終更新日 | 2023-05-10 | | 実験手法 | ELECTRON MICROSCOPY (2.75 Å) | | 主引用文献 | Structure, sequon recognition and mechanism of tryptophan C-mannosyltransferase.
Nat.Chem.Biol., 19, 2023
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7T8D
 | | Myocilin OLF mutant V449I | | 分子名称: | CALCIUM ION, GLYCEROL, Myocilin, ... | | 著者 | Scelsi, H.S, Barlow, B.M, Lieberman, R.L. | | 登録日 | 2021-12-16 | | 公開日 | 2023-01-11 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | | 主引用文献 | Quantitative differentiation of benign and misfolded glaucoma-causing myocilin variants on the basis of protein thermal stability.
Dis Model Mech, 16, 2023
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7U63
 | | Crystal Structure Anti-Oxycodone Antibody HY2-A12 Fab Complexed with Oxycodone | | 分子名称: | 14-hydroxy-3-methoxy-17-methyl-5beta-4,5-epoxymorphinan-6-one, HY2-A12 Fab Heavy Chain, HY2-A12 Fab Light Chain | | 著者 | Rodarte, J.V, Pancera, M.P, Weidle, C, Rupert, P.B, Strong, R.K. | | 登録日 | 2022-03-03 | | 公開日 | 2023-01-11 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structures of drug-specific monoclonal antibodies bound to opioids and nicotine reveal a common mode of binding.
Structure, 31, 2023
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7YL7
 | | Structure of hIAPP-TF-type3 | | 分子名称: | Islet amyloid polypeptide | | 著者 | Li, D, Zhang, X. | | 登録日 | 2022-07-25 | | 公開日 | 2022-12-28 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | A new polymorphism of human amylin fibrils with similar protofilaments and a conserved core.
Iscience, 25, 2022
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7YL3
 | | Structure of hIAPP-TF-type1 | | 分子名称: | Islet amyloid polypeptide | | 著者 | Li, D, Zhang, X, Wang, Y, Zhu, P. | | 登録日 | 2022-07-25 | | 公開日 | 2022-12-28 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | A new polymorphism of human amylin fibrils with similar protofilaments and a conserved core.
Iscience, 25, 2022
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7YL0
 | | Structure of hIAPP-TF-type2 | | 分子名称: | Islet amyloid polypeptide | | 著者 | Li, D, Zhang, X, Wang, Y, Zhu, P. | | 登録日 | 2022-07-25 | | 公開日 | 2022-12-28 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | A new polymorphism of human amylin fibrils with similar protofilaments and a conserved core.
Iscience, 25, 2022
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7UQ3
 | | JmjC domain-containing protein 5 (JMJD5) in complex with Mn and (S)-2-(1-hydroxy-2,5-dioxopyrrolidin-3-yl)acetic acid | | 分子名称: | Bifunctional peptidase and arginyl-hydroxylase JMJD5, GLYCEROL, MANGANESE (II) ION, ... | | 著者 | Chowdhury, R, Islam, M.S, Schofield, C.J. | | 登録日 | 2022-04-19 | | 公開日 | 2022-12-21 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | | 主引用文献 | Structural analysis of the 2-oxoglutarate binding site of the circadian rhythm linked oxygenase JMJD5.
Sci Rep, 12, 2022
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7XD9
 | | Crystal Structure of Dengue Virus serotype 2 (DENV2) Polymerase Elongation Complex (CTP Form) | | 分子名称: | CYTIDINE-5'-TRIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ... | | 著者 | Wu, J, Wang, X, Gong, P. | | 登録日 | 2022-03-26 | | 公開日 | 2022-12-21 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.58 Å) | | 主引用文献 | Structural basis of transition from initiation to elongation in de novo viral RNA-dependent RNA polymerases.
Proc.Natl.Acad.Sci.USA, 120, 2023
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7XD8
 | | Crystal Structure of Dengue Virus Serotype 2 (DENV2) Polymerase Elongation Complex (Native Form) | | 分子名称: | GLYCEROL, NS5, RNA (30-mer), ... | | 著者 | Wu, J, Wang, X, Gong, P. | | 登録日 | 2022-03-26 | | 公開日 | 2022-12-21 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Structural basis of transition from initiation to elongation in de novo viral RNA-dependent RNA polymerases.
Proc.Natl.Acad.Sci.USA, 120, 2023
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8BV0
 | | Binary complex between the NB-ARC domain from the Tomato immune receptor NRC1 and the SPRY domain-containing effector SS15 from the potato cyst nematode | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, NRC1, Truncated secreted SPRY domain-containing protein 15 (Fragment) | | 著者 | Contreras, M.P, Pai, H, Muniyandi, S, Toghani, A, Lawson, D.M, Tumtas, Y, Duggan, C, Yuen, E.L.H, Stevenson, C.E.M, Harant, A, Wu, C.H, Bozkurt, T.O, Kamoun, S, Derevnina, L. | | 登録日 | 2022-12-01 | | 公開日 | 2022-12-21 | | 最終更新日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (4.5 Å) | | 主引用文献 | Resurrection of plant disease resistance proteins via helper NLR bioengineering.
Sci Adv, 9, 2023
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7T1E
 | | Structure of monomeric and dimeric human CCL20 | | 分子名称: | C-C motif chemokine 20, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | | 著者 | Peterson, F.C, Riutta, S.J, Volkman, B.F. | | 登録日 | 2021-12-01 | | 公開日 | 2022-12-14 | | 最終更新日 | 2024-06-26 | | 実験手法 | X-RAY DIFFRACTION (1.459 Å) | | 主引用文献 | The Chemokine, CCL20, and Its Receptor, CCR6, in the Pathogenesis and Treatment of Psoriasis and Psoriatic Arthritis
J Psoriasis Psoriatic Arthritis, 8, 2023
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8D8I
 | | Crystal structure of Reverb alpha in complex with synthetic agonist | | 分子名称: | (4S)-6-[([1,1'-biphenyl]-2-yl)oxy]-3-chloro[1,2,4]triazolo[4,3-b]pyridazine, Nuclear receptor corepressor 1, Nuclear receptor subfamily 1 group D member 1 | | 著者 | Ronin, C, Ciesielski, F, Hegazy, L, Burris, P.T. | | 登録日 | 2022-06-08 | | 公開日 | 2022-12-14 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.504 Å) | | 主引用文献 | Structural basis of synthetic agonist activation of the nuclear receptor REV-ERB.
Nat Commun, 13, 2022
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7X9F
 | | Crystal structure of actinomycin D-echinomycin-d(AGCGCGT/ACGCGCT) complex | | 分子名称: | 2-CARBOXYQUINOXALINE, DNA (5'-D(P*AP*CP*GP*CP*GP*CP*T)-3'), DNA (5'-D(P*AP*GP*CP*GP*CP*GP*T)-3'), ... | | 著者 | Kao, S.H, Satange, R.B, Hou, M.H. | | 登録日 | 2022-03-15 | | 公開日 | 2022-12-14 | | 最終更新日 | 2024-07-10 | | 実験手法 | X-RAY DIFFRACTION (2.96 Å) | | 主引用文献 | Staggered intercalation of DNA duplexes with base-pair modulation by two distinct drug molecules induces asymmetric backbone twisting and structure polymorphism.
Nucleic Acids Res., 50, 2022
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7X6R
 | | Crystal structure of actinomycin D-echinomycin-d(AGCACGT/ACGGGCT) complex | | 分子名称: | 2-CARBOXYQUINOXALINE, Actinomycin D, COBALT (II) ION, ... | | 著者 | Kao, S.H, Satange, R.B, Hou, M.H. | | 登録日 | 2022-03-08 | | 公開日 | 2022-12-14 | | 最終更新日 | 2024-07-10 | | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | | 主引用文献 | Staggered intercalation of DNA duplexes with base-pair modulation by two distinct drug molecules induces asymmetric backbone twisting and structure polymorphism.
Nucleic Acids Res., 50, 2022
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7X97
 | | Crystal structure of actinomycin D-echinomycin-d(AGCCCGT/ACGGGCT) complex | | 分子名称: | 2-CARBOXYQUINOXALINE, Actinomycin D, CHLORIDE ION, ... | | 著者 | Kao, S.H, Satange, R.B, Hou, M.H. | | 登録日 | 2022-03-15 | | 公開日 | 2022-12-14 | | 最終更新日 | 2024-07-10 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Staggered intercalation of DNA duplexes with base-pair modulation by two distinct drug molecules induces asymmetric backbone twisting and structure polymorphism.
Nucleic Acids Res., 50, 2022
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7XDJ
 | | Crystal structure of actinomycin D-echinomycin-d(AGCGCGT/ACGAGCT) complex | | 分子名称: | 2-CARBOXYQUINOXALINE, CHLORIDE ION, DNA (5'-D(P*AP*CP*GP*AP*GP*CP*(BRU))-3'), ... | | 著者 | Chien, C.M, Satange, R.B, Hou, M.H. | | 登録日 | 2022-03-27 | | 公開日 | 2022-12-14 | | 最終更新日 | 2024-07-10 | | 実験手法 | X-RAY DIFFRACTION (2.435 Å) | | 主引用文献 | Staggered intercalation of DNA duplexes with base-pair modulation by two distinct drug molecules induces asymmetric backbone twisting and structure polymorphism.
Nucleic Acids Res., 50, 2022
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7W4R
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7W4W
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7W4T
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7W4U
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7W4S
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7W4V
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8AGE
 | | Structure of yeast oligosaccharylransferase complex with acceptor peptide bound | | 分子名称: | (2~{S},3~{R},4~{R},5~{S},6~{S})-2-(hydroxymethyl)-6-[(1~{S},2~{R},3~{R},4~{R},5'~{S},6~{S},7~{R},8~{S},9~{R},12~{R},13~{R},15~{S},16~{S},18~{R})-5',7,9,13-tetramethyl-3,15-bis(oxidanyl)spiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icosane-6,2'-oxane]-16-yl]oxy-oxane-3,4,5-triol, 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-[3,6-bis(dimethylamino)xanthen-9-yl]-5-methanoyl-benzoate, ... | | 著者 | Ramirez, A.S, de Capitani, M, Pesciullesi, G, Kowal, J, Bloch, J.S, Irobalieva, R.N, Aebi, M, Reymond, J.L, Locher, K.P. | | 登録日 | 2022-07-19 | | 公開日 | 2022-12-07 | | 最終更新日 | 2023-10-18 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Molecular basis for glycan recognition and reaction priming of eukaryotic oligosaccharyltransferase.
Nat Commun, 13, 2022
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8AGB
 | | Structure of yeast oligosaccharylransferase complex with lipid-linked oligosaccharide bound | | 分子名称: | 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Ramirez, A.S, de Capitani, M, Pesciullesi, G, Kowal, J, Bloch, J.S, Irobalieva, R.N, Aebi, M, Reymond, J.L, Locher, K.P. | | 登録日 | 2022-07-19 | | 公開日 | 2022-12-07 | | 最終更新日 | 2023-10-18 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Molecular basis for glycan recognition and reaction priming of eukaryotic oligosaccharyltransferase.
Nat Commun, 13, 2022
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8AGC
 | | Structure of yeast oligosaccharylransferase complex with lipid-linked oligosaccharide and non-acceptor peptide bound | | 分子名称: | 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-[3,6-bis(dimethylamino)xanthen-9-yl]-5-methanoyl-benzoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Ramirez, A.S, de Capitani, M, Pesciullesi, G, Kowal, J, Bloch, J.S, Irobalieva, R.N, Aebi, M, Reymond, J.L, Locher, K.P. | | 登録日 | 2022-07-19 | | 公開日 | 2022-12-07 | | 最終更新日 | 2023-10-18 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Molecular basis for glycan recognition and reaction priming of eukaryotic oligosaccharyltransferase.
Nat Commun, 13, 2022
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