7T8D
Myocilin OLF mutant V449I
Summary for 7T8D
| Entry DOI | 10.2210/pdb7t8d/pdb |
| Descriptor | Myocilin, C-terminal fragment, CALCIUM ION, SODIUM ION, ... (5 entities in total) |
| Functional Keywords | olfactomedin, beta-propeller, cell adhesion |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 1 |
| Total formula weight | 31366.17 |
| Authors | Scelsi, H.S.,Barlow, B.M.,Lieberman, R.L. (deposition date: 2021-12-16, release date: 2023-01-11, Last modification date: 2023-10-25) |
| Primary citation | Scelsi, H.F.,Hill, K.R.,Barlow, B.M.,Martin, M.D.,Lieberman, R.L. Quantitative differentiation of benign and misfolded glaucoma-causing myocilin variants on the basis of protein thermal stability. Dis Model Mech, 16:-, 2023 Cited by PubMed: 36579626DOI: 10.1242/dmm.049816 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.38 Å) |
Structure validation
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