8AGC

Structure of yeast oligosaccharylransferase complex with lipid-linked oligosaccharide and non-acceptor peptide bound

Summary for 8AGC

• Entry DOI: 10.2210/pdb8agc/pdb
• EMDB information: 15420
• Descriptor: Dolichyl-diphosphooligosaccharide--protein glycotransferase, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (18 entities in total)
• Functional Keywords: n-glycosylation ost complex, transferase
• Biological source: Saccharomyces cerevisiae (baker's yeast); More
• Total number of polymer chains: 9
• Total formula weight: 297648.38

Authors

Ramirez, A.S.,de Capitani, M.,Pesciullesi, G.,Kowal, J.,Bloch, J.S.,Irobalieva, R.N.,Aebi, M.,Reymond, J.L.,Locher, K.P. (deposition date: 2022-07-19, release date: 2022-12-07, Last modification date: 2023-10-18)

• Primary citation: Ramirez, A.S.,de Capitani, M.,Pesciullesi, G.,Kowal, J.,Bloch, J.S.,Irobalieva, R.N.,Reymond, J.L.,Aebi, M.,Locher, K.P.; Molecular basis for glycan recognition and reaction priming of eukaryotic oligosaccharyltransferase.; Nat Commun, 13:7296-7296, 2022; PubMed: 36435935; DOI: 10.1038/s41467-022-35067-x

Experimental method

ELECTRON MICROSCOPY (3.1 Å)