PDB: 82203 件ウェブページステータス検索Chemie searchBIRD

---

4LHO	Crystal Structure of FG41Malonate Semialdehyde Decarboxylase inhibited by 3-bromopropiolate 分子名称: 3-chloro-3-oxopropanoic acid, FG41 Malonate Semialdehyde Decarboxylase, PHOSPHATE ION 著者 Guo, Y, Serrano, H, Poelarends, G.J, Johnson Jr, W.H, Hackert, M.L, Whitman, C.P. 登録日 2013-07-01 公開日 2013-07-24 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.224 Å) 主引用文献 Kinetic, Mutational, and Structural Analysis of Malonate Semialdehyde Decarboxylase from Coryneform Bacterium Strain FG41: Mechanistic Implications for the Decarboxylase and Hydratase Activities. Biochemistry, 52, 2013
1RMO	Probing the Role of Tryptophans in Aequorea Victoria Green Fluorescent Proteins with an Expanded Genetic Code 分子名称: wunen-nonfunctional GFP fusion protein 著者 Budisa, N, Pal, P.P, Alefelder, S, Birle, P, Krywcun, T, Rubini, M, Wenger, W, Bae, J.H, Steiner, T. 登録日 2003-11-28 公開日 2004-06-08 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Probing the role of tryptophans in Aequorea victoria green fluorescent proteins with an expanded genetic code Biol.Chem., 385, 2004
1RM9	Probing the Role of Tryptophans in Aequorea Victoria Green Fluorescent Proteins with an Expanded Genetic Code 分子名称: avermectin-sensitive chloride channel GluCl beta/cyan fluorescent protein fusion 著者 Budisa, N, Pal, P.P, Alefelder, S, Birle, P, Krywcun, T, Rubini, M, Wenger, W, Bae, J.H, Steiner, T. 登録日 2003-11-27 公開日 2004-06-08 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Probing the role of tryptophans in Aequorea victoria green fluorescent proteins with an expanded genetic code Biol.Chem., 385, 2004
1RMP	Probing the Role of Tryptophans in Aequorea Victoria Green Fluorescent Proteins with an Expanded Genetic Code 分子名称: SIGF1-GFP fusion protein 著者 Budisa, N, Pal, P.P, Alefelder, S, Birle, P, Krywcun, T, Rubini, M, Wenger, W, Bae, J.H, Steiner, T. 登録日 2003-11-28 公開日 2004-06-08 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Probing the role of tryptophans in Aequorea victoria green fluorescent proteins with an expanded genetic code Biol.Chem., 385, 2004
1A8W	A K+ CATION-INDUCED CONFORMATIONAL SWITCH WITHIN A LOOP SPANNING SEGMENT OF A DNA QUADRUPLEX CONTAINING G-G-G-C REPEATS, NMR, 8 STRUCTURES 分子名称: DNA QUADRUPLEX CONTAINING GGGG TETRADS AND GC WATSON-CRICK BASE PAIRS 著者 Bouaziz, S, Kettani, A, Patel, D.J. 登録日 1998-03-28 公開日 1998-10-14 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 A K cation-induced conformational switch within a loop spanning segment of a DNA quadruplex containing G-G-G-C repeats. J.Mol.Biol., 282, 1998
4YI3	Crystal structure of Gpb in complex with 4a 分子名称: DIMETHYL SULFOXIDE, Glycogen phosphorylase, muscle form, ... 著者 Kantsadi, A.L, Chatzileontiadou, D.S.M, Stravodimos, G.A, Leonidas, D.D. 登録日 2015-02-27 公開日 2015-11-18 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Glycogen phosphorylase as a target for type 2 diabetes: synthetic, biochemical, structural and computational evaluation of novel N-acyl-N -( beta-D-glucopyranosyl) urea inhibitors. Curr Top Med Chem, 15, 2015
4X6X	Human soluble epoxide hydrolase in complex with a three substituted cyclopropane derivative 分子名称: 3-{4-[(1-{[(1s,2R,3S)-2,3-diphenylcyclopropyl]carbamoyl}piperidin-4-yl)oxy]phenyl}propanoic acid, Bifunctional epoxide hydrolase 2 著者 Chiyo, N, Takai, K, Ishii, T. 登録日 2014-12-09 公開日 2015-04-08 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Three-dimensional rational approach to the discovery of potent substituted cyclopropyl urea soluble epoxide hydrolase inhibitors. Bioorg.Med.Chem.Lett., 25, 2015
7VHY	Crystal structure of EP300 HAT domain in complex with compound (+)-3 分子名称: Histone acetyltransferase p300, ZINC ION, [(6R)-6-(1H-indazol-4-ylmethyl)-1,4-oxazepan-4-yl]-[1-(4-methoxyphenyl)cyclopentyl]methanone 著者 Takahashi, M, Hanzawa, H. 登録日 2021-09-24 公開日 2022-04-27 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Discovery of EP300/CBP histone acetyltransferase inhibitors through scaffold hopping of 1,4-oxazepane ring. Bioorg.Med.Chem.Lett., 66, 2022
1RCV	Cholera Toxin B-Pentamer Complexed With Bivalent Nitrophenol-Galactoside Ligand BV1 分子名称: [3-(4-{3-[3-NITRO-5-(GALACTOPYRANOSYLOXY)-BENZOYLAMINO]-PROPYL}-PIPERAZIN-1-YL)-PROPYLAMINO] -2-(3-{4-[3-(3-NITRO-5-[GALACTOPYRANOSYLOXY]-BENZOYLAMINO)-PROPYL]-PIPERAZIN-1-YL} -PROPYL-AMINO)-3,4-DIOXO-CYCLOBUTENE, cholera toxin B protein (CTB) 著者 Pickens, J.C, Mitchell, D.D, Liu, J, Tan, X, Zhang, Z, Verlinde, C.L, Hol, W.G, Fan, E. 登録日 2003-11-04 公開日 2004-10-26 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Nonspanning bivalent ligands as improved surface receptor binding inhibitors of the cholera toxin B pentamer. Chem.Biol., 11, 2004
3C3S	Role of a Glutamate Bridge Spanning the Dimeric Interface of Human Manganese Superoxide Dismutase 分子名称: MANGANESE (II) ION, SULFATE ION, Superoxide dismutase [Mn] 著者 Quint, P.S, Domsic, J.F, Cabelli, D.E, McKenna, R, Silverman, D.N. 登録日 2008-01-28 公開日 2008-04-22 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Role of a glutamate bridge spanning the dimeric interface of human manganese superoxide dismutase. Biochemistry, 47, 2008
4M5Z	Crystal structure of broadly neutralizing antibody 5J8 bound to 2009 pandemic influenza hemagglutinin, HA1 subunit 分子名称: Fab 5J8 heavy chain, Fab 5J8 light chain, Hemagglutinin HA1 chain 著者 Hong, M, Lee, P.S, Wilson, I.A. 登録日 2013-08-08 公開日 2013-09-25 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Antibody Recognition of the Pandemic H1N1 Influenza Virus Hemagglutinin Receptor Binding Site. J.Virol., 87, 2013
3C3T	Role of a Glutamate Bridge Spanning the Dimeric Interface of Human Manganese Superoxide Dismutase 分子名称: MANGANESE (II) ION, SULFATE ION, Superoxide dismutase [Mn] 著者 Quint, P.S, Domsic, J.F, Cabelli, D.E, McKenna, R, Silverman, D.N. 登録日 2008-01-28 公開日 2008-04-22 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Role of a glutamate bridge spanning the dimeric interface of human manganese superoxide dismutase. Biochemistry, 47, 2008
2ZBB	P43 crystal of DctBp 分子名称: C4-dicarboxylate transport sensor protein dctB, MALONIC ACID 著者 Zhou, Y.F, Nan, B.Y, Liu, X, Nan, J, Liang, Y.H, Panjikar, S, Ma, Q.J, Wang, Y.P, Su, X.-D. 登録日 2007-10-18 公開日 2008-11-18 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 crystal structures of sensory histidine kinase DctBp to be published
2XYS	Crystal structure of Aplysia californica AChBP in complex with strychnine 分子名称: SOLUBLE ACETYLCHOLINE RECEPTOR, STRYCHNINE 著者 Brams, M, Pandya, A, Kuzmin, D, van Elk, R, Krijnen, L, Yakel, J.L, Tsetlin, V, Smit, A.B, Ulens, C. 登録日 2010-11-19 公開日 2011-03-23 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.909 Å) 主引用文献 A Structural and Mutagenic Blueprint for Molecular Recognition of Strychnine and D-Tubocurarine by Different Cys-Loop Receptors. Plos Biol., 9, 2011
5G0R	METHYL-COENZYME M REDUCTASE I FROM METHANOTHERMOBACTER MARBURGENSIS EXPOSED TO 3-NITROOXYPROPANOL 分子名称: CHLORIDE ION, Coenzyme B, FACTOR 430, ... 著者 Wagner, T. 登録日 2016-03-22 公開日 2016-04-13 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 Mode of Action Uncovered for the Specific Reduction of Methane Emissions from Ruminants by the Small Molecule 3-Nitrooxypropanol. Proc.Natl.Acad.Sci.USA, 113, 2016
2XYT	Crystal structure of Aplysia californica AChBP in complex with d- tubocurarine 分子名称: D-TUBOCURARINE, SOLUBLE ACETYLCHOLINE RECEPTOR 著者 Brams, M, Pandya, A, Kuzmin, D, van Elk, R, Krijnen, L, Yakel, J.L, Tsetlin, V, Smit, A.B, Ulens, C. 登録日 2010-11-19 公開日 2011-03-23 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 A Structural and Mutagenic Blueprint for Molecular Recognition of Strychnine and D-Tubocurarine by Different Cys-Loop Receptors. Plos Biol., 9, 2011
5DP2	CurF ER cyclopropanase from curacin A biosynthetic pathway 分子名称: CurF, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Khare, D, Smith, J.L. 登録日 2015-09-12 公開日 2015-11-18 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (0.96 Å) 主引用文献 Structural Basis for Cyclopropanation by a Unique Enoyl-Acyl Carrier Protein Reductase. Structure, 23, 2015
6J1M	Anisodus acutangulus type III polyketide sythase AaPKS2 in complex with 4-carboxy-3-oxobutanoyl covalent to C166 分子名称: 1,2-ETHANEDIOL, 3-oxopentanedioic acid, A. acutangulus PKS2 著者 Fang, C.L, Zhang, Y. 登録日 2018-12-28 公開日 2019-09-11 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.001 Å) 主引用文献 Tropane alkaloids biosynthesis involves an unusual type III polyketide synthase and non-enzymatic condensation. Nat Commun, 10, 2019
2QYT	Crystal structure of 2-dehydropantoate 2-reductase from Porphyromonas gingivalis W83 分子名称: 1,2-ETHANEDIOL, 2-dehydropantoate 2-reductase, SULFATE ION 著者 Tan, K, Wu, R, Moy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) 登録日 2007-08-15 公開日 2007-09-04 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 The crystal structure of 2-dehydropantoate 2-reductase from Porphyromonas gingivalis W83. To be Published
1VZI	Structure of superoxide reductase bound to ferrocyanide and active site expansion upon X-ray induced photoreduction 分子名称: CALCIUM ION, CHLORIDE ION, DESULFOFERRODOXIN, ... 著者 Adam, V, Royant, A, Niviere, V, Molina-Heredia, F.P, Bourgeois, D. 登録日 2004-05-19 公開日 2004-08-27 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.15 Å) 主引用文献 Structure of superoxide reductase bound to ferrocyanide and active site expansion upon X-ray-induced photo-reduction. Structure, 12, 2004
5L16	Crystal Structure of N-terminus truncated selenophosphate synthetase from Leishmania major 分子名称: Putative selenophosphate synthetase, SULFATE ION 著者 Faim, L.M, Silva, I.R, Pereira, H.M, Dias, M.B, Silva, M.T.A, Brandao-Neto, J, Thiemann, O.H. 登録日 2016-07-28 公開日 2017-08-09 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.882 Å) 主引用文献 Trypanosomatid selenophosphate synthetase structure, function and interaction with selenocysteine lyase. Plos Negl Trop Dis, 14, 2020
5BQI	Discovery of a Potent and Selective mPGES-1 Inhibitor for the Treatment of Pain 分子名称: (2-hydroxyethoxy)acetaldehyde, 2-(difluoromethyl)-5-{[(2-methylpropanoyl)amino]methyl}-N-{5-methyl-4-[4-(trifluoromethyl)phenyl]-1H-imidazol-2-yl}pyridine-3-carboxamide, GLUTATHIONE, ... 著者 Fisher, M.J, Schiffler, M.A, Kuklish, S.L, Antonysamy, S, Luz, J.G. 登録日 2015-05-29 公開日 2016-04-13 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Discovery and Characterization of 2-Acylaminoimidazole Microsomal Prostaglandin E Synthase-1 Inhibitors. J.Med.Chem., 59, 2016
5MVR	Crystal structure of Bacillus subtilus YdiB 分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... 著者 Jault, J.-M, Aghajari, N. 登録日 2017-01-17 公開日 2017-09-20 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.762 Å) 主引用文献 Expanding the Kinome World: A New Protein Kinase Family Widely Conserved in Bacteria. J. Mol. Biol., 429, 2017
5M9U	Spatial structure of antimicrobial peptide arenicin-1 mutant V8R 分子名称: Arenicin-1 著者 Myshkin, M.Y, Shenkarev, Z.O, Panteleev, P.V, Ovchinnikova, T.V. 登録日 2016-11-02 公開日 2017-07-26 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Dimerization of the antimicrobial peptide arenicin plays a key role in the cytotoxicity but not in the antibacterial activity. Biochem. Biophys. Res. Commun., 482, 2017
2WIH	STRUCTURE OF CDK2-CYCLIN A WITH PHA-848125 分子名称: CELL DIVISION PROTEIN KINASE 2, CYCLIN-A2, N,1,4,4-TETRAMETHYL-8-{[4-(4-METHYLPIPERAZIN-1-YL)PHENYL]AMINO}-4,5-DIHYDRO-1H-PYRAZOLO[4,3-H]QUINAZOLINE-3-CARBOXAMIDE, ... 著者 Brasca, M.G, Amboldi, N, Ballinari, D, Cameron, A.D, Casale, E, Cervi, G, Colombo, M, Colotta, F, Croci, V, Dalessio, R, Fiorentini, F, Isacchi, A, Mercurio, C, Moretti, W, Panzeri, A, Pastori, W, Pevarello, P, Quartieri, F, Roletto, F, Traquandi, G, Vianello, P, Vulpetti, A, Ciomei, M. 登録日 2009-05-13 公開日 2009-07-28 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Identification of N,1,4,4-Tetramethyl-8-{[4-(4-Methylpiperazin-1-Yl)Phenyl]Amino}-4,5-Dihydro-1H-Pyrazolo[4,3-H]Quinazoline-3-Carboxamide (Pha-848125), a Potent, Orally Available Cyclin Dependent Kinase Inhibitor. J.Med.Chem., 52, 2009

<212213214215216217218219220221222223224225226227>